Small-molecule inhibitors of protein-protein interactions: progressing toward the reality.
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Process of Fragment-Based Lead Discovery-A Perspective from NMRIntracellular targeting with engineered proteinsDevelopment of lifitegrast: a novel T-cell inhibitor for the treatment of dry eye diseaseModulation of Protein-Protein Interactions for the Development of Novel TherapeuticsMulti-Facial, Non-Peptidic α-Helix MimeticsDirect and Propagated Effects of Small Molecules on Protein-Protein Interaction NetworksSmall Molecule Targeting of Protein-Protein Interactions through Allosteric Modulation of DynamicsThe biology of IQGAP proteins: beyond the cytoskeletonDeconvolution method for specific and nonspecific binding of ligand to multiprotein complex by native mass spectrometry.A High-Throughput Small Molecule Screen for C. elegans Linker Cell Death InhibitorsStabilizer-Guided Inhibition of Protein-Protein InteractionsSmall-Molecule Stabilization of the 14-3-3/Gab2 Protein-Protein Interaction (PPI) InterfaceEngineering archeal surrogate systems for the development of protein-protein interaction inhibitors against human RAD51Characterization of Protein-Protein Interfaces through a Protein Contact Network ApproachEnhancements to the Rosetta Energy Function Enable Improved Identification of Small Molecules that Inhibit Protein-Protein InteractionsIdentification of Polo-like kinase 1 interaction inhibitors using a novel cell-based assayStructural basis for small molecule targeting of the programmed death ligand 1 (PD-L1)Discovery and characterization of smORF-encoded bioactive polypeptidesPotent and selective inhibition of pathogenic viruses by engineered ubiquitin variants.Bacterial flagellar capping proteins adopt diverse oligomeric states.Small Molecule Inhibitor of CBFβ-RUNX Binding for RUNX Transcription Factor Driven CancersDirect inhibition of c-Myc-Max heterodimers by celastrol and celastrol-inspired triterpenoids.Protein-Protein Interactions Mediated by Helical Tertiary Structure Motifs.Broad Spectrum Anti-Influenza Agents by Inhibiting Self-Association of Matrix Protein 1.The evolution of regulators of G protein signalling proteins as drug targets - 20 years in the making: IUPHAR Review 21.Genetic visualization of protein interactions harnessing liquid phase transitionsIdentification of an in vivo orally active dual-binding protein-protein interaction inhibitor targeting TNFα through combined in silico/in vitro/in vivo screeningPIPINO: A Software Package to Facilitate the Identification of Protein-Protein Interactions from Affinity Purification Mass Spectrometry DataCyclin D mediates tolerance of genome-doubling in cancers with functional p53.Inducing death in tumor cells: roles of the inhibitor of apoptosis proteins.A protein-protein interaction dictates Borrelial infectivity.β-Turn mimetic-based stabilizers of protein-protein interactions for the study of the non-canonical roles of leucyl-tRNA synthetase.Essential multimeric enzymes in kinetoplastid parasites: A host of potentially druggable protein-protein interactions.Targeting Cullin-RING E3 ubiquitin ligases for drug discovery: structure, assembly and small-molecule modulation.Overcoming Chemical, Biological, and Computational Challenges in the Development of Inhibitors Targeting Protein-Protein Interactions.Folding and function in α/β-peptides: targets and therapeutic applications.Targeting diverse protein-protein interaction interfaces with α/β-peptides derived from the Z-domain scaffold.TNF superfamily protein-protein interactions: feasibility of small- molecule modulationInhibitors of the apurinic/apyrimidinic endonuclease 1 (APE1)/nucleophosmin (NPM1) interaction that display anti-tumor propertiesAlternative modulation of protein-protein interactions by small molecules
P2860
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P2860
Small-molecule inhibitors of protein-protein interactions: progressing toward the reality.
description
2014 nî lūn-bûn
@nan
2014 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Small-molecule inhibitors of p ...... rogressing toward the reality.
@ast
Small-molecule inhibitors of p ...... rogressing toward the reality.
@en
Small-molecule inhibitors of p ...... rogressing toward the reality.
@nl
type
label
Small-molecule inhibitors of p ...... rogressing toward the reality.
@ast
Small-molecule inhibitors of p ...... rogressing toward the reality.
@en
Small-molecule inhibitors of p ...... rogressing toward the reality.
@nl
prefLabel
Small-molecule inhibitors of p ...... rogressing toward the reality.
@ast
Small-molecule inhibitors of p ...... rogressing toward the reality.
@en
Small-molecule inhibitors of p ...... rogressing toward the reality.
@nl
P2093
P2860
P1476
Small-molecule inhibitors of p ...... rogressing toward the reality.
@en
P2093
James A Wells
Michelle R Arkin
Yinyan Tang
P2860
P304
P356
10.1016/J.CHEMBIOL.2014.09.001
P577
2014-09-01T00:00:00Z