Functional characterization of Anaphase Promoting Complex/Cyclosome (APC/C) E3 ubiquitin ligases in tumorigenesis - Test2 - elhamkhani - TriplyDB

Functional characterization of Anaphase Promoting Complex/Cyclosome (APC/C) E3 ubiquitin ligases in tumorigenesis

Functional characterization of Anaphase Promoting Complex/Cyclosome (APC/C) E3 ubiquitin ligases in tumorigenesis

http://www.wikidata.org/entity/Q26998944

about

Insights into APC/C: from cellular function to diseases and therapeutics NEDD4: a promising target for cancer therapy Parkin Regulates Mitosis and Genomic Stability through Cdc20/Cdh1.Targeting of Fzr/Cdh1 for timely activation of the APC/C at the centrosome during mitotic exit.APC/C and retinoblastoma interaction: cross-talk of retinoblastoma protein with the ubiquitin proteasome pathway Phosphoproteomic Profiling Reveals Epstein-Barr Virus Protein Kinase Integration of DNA Damage Response and Mitotic Signaling Defective sister chromatid cohesion is synthetically lethal with impaired APC/C function.The dynamics of signal amplification by macromolecular assemblies for the control of chromosome segregation Comprehensive exploration of novel chimeric transcripts in clear cell renal cell carcinomas using whole transcriptome analysis Whole-exome sequencing reveals the mutational spectrum of testicular germ cell tumours.Targeting Cdc20 as a novel cancer therapeutic strategy.DNA-PKcs Negatively Regulates Cyclin B1 Protein Stability through Facilitating Its Ubiquitination Mediated by Cdh1-APC/C Pathway.A new scheme to discover functional associations and regulatory networks of E3 ubiquitin ligases.Comparison of gene expression response to neutron and x-ray irradiation using mouse blood Cdh1 inhibits WWP2-mediated ubiquitination of PTEN to suppress tumorigenesis in an APC-independent manner Mitotic degradation of yeast Fkh1 by the Anaphase Promoting Complex is required for normal longevity, genomic stability and stress resistance.APC/C and SCF(cyclin F) Constitute a Reciprocal Feedback Circuit Controlling S-Phase Entry.A CARP-1 functional mimetic loaded vitamin E-TPGS micellar nano-formulation for inhibition of renal cell carcinoma.Pirh2 mediates the sensitivity of myeloma cells to bortezomib via canonical NF-κB signaling pathway.Specific targeting of the deubiquitinase and E3 ligase families with engineered ubiquitin variants.The APC/C E3 Ligase Complex Activator FZR1 Restricts BRAF Oncogenic Function.Prostate cancer-associated mutation in SPOP impairs its ability to target Cdc20 for poly-ubiquitination and degradation.Shugoshin 1 is dislocated by KSHV-encoded LANA inducing aneuploidy

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P2860

Functional characterization of Anaphase Promoting Complex/Cyclosome (APC/C) E3 ubiquitin ligases in tumorigenesis

http://www.wikidata.org/entity/Q26998944

description

2014 nî lūn-bûn

@nan

2014 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի ապրիլին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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name

Functional characterization of ...... uitin ligases in tumorigenesis

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Functional characterization of ...... uitin ligases in tumorigenesis

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Functional characterization of ...... uitin ligases in tumorigenesis

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type

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Functional characterization of ...... uitin ligases in tumorigenesis

@ast

Functional characterization of ...... uitin ligases in tumorigenesis

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Functional characterization of ...... uitin ligases in tumorigenesis

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prefLabel

Functional characterization of ...... uitin ligases in tumorigenesis

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Functional characterization of ...... uitin ligases in tumorigenesis

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Functional characterization of ...... uitin ligases in tumorigenesis

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P1433

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J.BBCAN.2014.02.001

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Biochimica et Biophysica Acta

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Functional characterization of ...... uitin ligases in tumorigenesis

@en

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Jinfang Zhang

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Lixin Wan

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Wenyi Wei

http://www.w3.org/2001/XMLSchema#string

Xiangpeng Dai

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Yi Sun

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P2860

Inhibition of Cdh1-APC by the MAD2-related protein MAD2L2: a novel mechanism for regulating Cdh1

MAD2B is an inhibitor of the anaphase-promoting complex

APC2 Cullin protein and APC11 RING protein comprise the minimal ubiquitin ligase module of the anaphase-promoting complex

Role of Polo-like kinase in the degradation of early mitotic inhibitor 1, a regulator of the anaphase promoting complex/cyclosome

E2F-dependent accumulation of hEmi1 regulates S phase entry by inhibiting APC(Cdh1)

Alterations of anaphase-promoting complex genes in human colon cancer cells

APC/C(Cdh1) targets brain-specific kinase 2 (BRSK2) for degradation via the ubiquitin-proteasome pathway

Emi1 stably binds and inhibits the anaphase-promoting complex/cyclosome as a pseudosubstrate inhibitor

Mitotic regulation of the human anaphase-promoting complex by phosphorylation

Pharmacologic inhibition of the anaphase-promoting complex induces a spindle checkpoint-dependent mitotic arrest in the absence of spindle damage

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277-93

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10.1016/J.BBCAN.2014.02.001

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3995847

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