A single-domain antibody fragment in complex with RNase A: non-canonical loop structures and nanomolar affinity using two CDR loops
about
Effector Functions of Camelid Heavy-Chain Antibodies in Immunity to West Nile VirusAntigen specificity and high affinity binding provided by one single loop of a camel single-domain antibodyThree camelid VHH domains in complex with porcine pancreatic alpha-amylase. Inhibition and versatility of binding topologySolution structure and backbone dynamics of an antigen-free heavy chain variable domain (VHH) from LlamaCrystal structure of the intrinsically flexible addiction antidote MazEHigh-affinity single-domain binding proteins with a binary-code interfaceExploring the Capacity of Minimalist Protein Interfaces: Interface Energetics and Affinity Maturation to Picomolar KD of a Single-domain Antibody with a Flat ParatopeComprehensive analysis of the factors contributing to the stability and solubility of autonomous human VH domainsToward chaperone-assisted crystallography: Protein engineering enhancement of crystal packing and X-ray phasing capabilities of a camelid single-domain antibody (VHH) scaffoldNanobody-aided structure determination of the EpsI:EpsJ pseudopilin heterodimer from Vibrio vulnificusStructural and thermodynamic analysis of the GFP:GFP-nanobody complexAn anti-hapten camelid antibody reveals a cryptic binding site with significant energetic contributions from a nonhypervariable loopA combinatorial histidine scanning library approach to engineer highly pH-dependent protein switchesReshaping Antibody DiversityB cell repertoires in HLA-sensitized kidney transplant candidates undergoing desensitization therapyProtein loop modeling using a new hybrid energy function and its application to modeling in inaccurate structural environments.Optimal design features of camelized human single-domain antibody libraries.Nanobodies as novel agents for cancer therapy.Design, expression, and stability of a diverse protein library based on the human fibronectin type III domainCamelid nanobodies raised against an integral membrane enzyme, nitric oxide reductaseA portable RNA sequence whose recognition by a synthetic antibody facilitates structural determination.Single-domain antibodies targeting neuraminidase protect against an H5N1 influenza virus challenge.Llama antibody fragments recognizing various epitopes of the CD4bs neutralize a broad range of HIV-1 subtypes A, B and C.Molecular basis for the preferential cleft recognition by dromedary heavy-chain antibodies.A general protocol for the generation of Nanobodies for structural biologyAnalysis and modeling of the variable region of camelid single-domain antibodies.Ligand-targeted theranostic nanomedicines against cancerSingle-domain antibody fragments with high conformational stability.Structure based antibody-like peptidomimetics.Evaluation of antidiphtheria toxin nanobodies.Nanobody; an old concept and new vehicle for immunotargeting.Immunoglobulin domains in Escherichia coli and other enterobacteria: from pathogenesis to applications in antibody technologies.High affinity anti-inorganic material antibody generation by integrating graft and evolution technologies: potential of antibodies as biointerface molecules.Camel heavy-chain antibodies: diverse germline V(H)H and specific mechanisms enlarge the antigen-binding repertoire.Single-Domain Antibodies As Versatile Affinity Reagents for Analytical and Diagnostic Applications.A peptide mimic of an antigenic loop of alpha-human chorionic gonadotropin hormone: solution structure and interaction with a llama V(HH) domain.Camelid Single-Domain Antibodies: Historical Perspective and Future Outlook.Domain swapping of a llama VHH domain builds a crystal-wide beta-sheet structure.Computational design of cyclic peptides for the customized oriented immobilization of globular proteins.An efficient protocol towards site-specifically clickable nanobodies in high yield: cytoplasmic expression in Escherichia coli combined with intein-mediated protein ligation.
P2860
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P2860
A single-domain antibody fragment in complex with RNase A: non-canonical loop structures and nanomolar affinity using two CDR loops
description
1999 nî lūn-bûn
@nan
1999 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
A single-domain antibody fragm ...... r affinity using two CDR loops
@ast
A single-domain antibody fragm ...... r affinity using two CDR loops
@en
A single-domain antibody fragm ...... r affinity using two CDR loops
@nl
type
label
A single-domain antibody fragm ...... r affinity using two CDR loops
@ast
A single-domain antibody fragm ...... r affinity using two CDR loops
@en
A single-domain antibody fragm ...... r affinity using two CDR loops
@nl
prefLabel
A single-domain antibody fragm ...... r affinity using two CDR loops
@ast
A single-domain antibody fragm ...... r affinity using two CDR loops
@en
A single-domain antibody fragm ...... r affinity using two CDR loops
@nl
P2093
P1433
P1476
A single-domain antibody fragm ...... r affinity using two CDR loops
@en
P2093
A Desmyter
K Decanniere
M A Ghahroudi
M Lauwereys
P304
P356
10.1016/S0969-2126(99)80049-5
P577
1999-04-15T00:00:00Z