High-affinity single-domain binding proteins with a binary-code interface - Test2 - elhamkhani - TriplyDB

High-affinity single-domain binding proteins with a binary-code interface

High-affinity single-domain binding proteins with a binary-code interface

http://www.wikidata.org/entity/Q27644389

about

Isoform-specific monobody inhibitors of small ubiquitin-related modifiers engineered using structure-guided library design Deep sequencing in library selection projects: what insight does it bring?Exploring the Capacity of Minimalist Protein Interfaces: Interface Energetics and Affinity Maturation to Picomolar KD of a Single-domain Antibody with a Flat Paratope Polymer-driven crystallization Synthetic antibodies for specific recognition and crystallization of structured RNA Toward chaperone-assisted crystallography: Protein engineering enhancement of crystal packing and X-ray phasing capabilities of a camelid single-domain antibody (VHH) scaffold Design of protein function leaps by directed domain interface evolution A Dominant Conformational Role for Amino Acid Diversity in Minimalist Protein–Protein Interfaces Molecular Mechanism of Thioflavin-T Binding to the Surface of β-Rich Peptide Self-Assemblies Pentameric Assembly of Potassium Channel Tetramerization Domain-Containing Protein 5 Structural Basis for Exquisite Specificity of Affinity Clamps, Synthetic Binding Proteins Generated through Directed Domain-interface Evolution A potent and highly specific FN3 monobody inhibitor of the Abl SH2 domain Allosteric control of ligand-binding affinity using engineered conformation-specific effector proteins Molecular Basis of a Million-Fold Affinity Maturation Process in a Protein–Protein Interaction Targeting the SH2-Kinase Interface in Bcr-Abl Inhibits Leukemogenesis Teaching an Old Scaffold New Tricks: Monobodies Constructed Using Alternative Surfaces of the FN3 Scaffold Design, construction, and characterization of a second-generation DARPin library with reduced hydrophobicity Selection of Specific Protein Binders for Pre-Defined Targets from an Optimized Library of Artificial Helicoidal Repeat Proteins (alphaRep)Mapping the conformational space accessible to BACE2 using surface mutants and cocrystals with Fab fragments, Fynomers and Xaperones Artificial affinity proteins as ligands of immunoglobulins Engineering of recombinant crystallization chaperones Crystal structures of MBP fusion proteins Thermodynamic additivity of sequence variations: an algorithm for creating high affinity peptides without large libraries or structural information Directed Evolution of a Highly Specific FN3 Monobody to the SH3 Domain of Human Lyn Tyrosine Kinase.The "Sticky Patch" Model of Crystallization and Modification of Proteins for Enhanced Crystallizability.Aromatic claw: A new fold with high aromatic content that evades structural prediction.Application of protein engineering to enhance crystallizability and improve crystal properties.Yeast surface display for protein engineering and characterization Picomolar affinity fibronectin domains engineered utilizing loop length diversity, recursive mutagenesis, and loop shuffling.High-throughput analysis of the protein sequence-stability landscape using a quantitative yeast surface two-hybrid system and fragment reconstitution The importance of being tyrosine: lessons in molecular recognition from minimalist synthetic binding proteins.Engineered cystine knot peptides that bind alphavbeta3, alphavbeta5, and alpha5beta1 integrins with low-nanomolar affinity.Accelerating phage-display library selection by reversible and site-specific biotinylation.The full amino acid repertoire is superior to serine/tyrosine for selection of high affinity immunoglobulin G binders from the fibronectin scaffold Protein-protein interactions and selection: generation of molecule-binding proteins on the basis of tertiary structural information.Stability and CDR composition biases enrich binder functionality landscapes.Monobodies and other synthetic binding proteins for expanding protein science Novel semisynthetic method for generating full length beta-amyloid peptides Engineering a protein-protein interface using a computationally designed library NextGen protein design.

P2860

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P2860

High-affinity single-domain binding proteins with a binary-code interface

http://www.wikidata.org/entity/Q27644389

description

2007 nî lūn-bûn

@nan

2007 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2007 թվականի ապրիլին հրատարակված գիտական հոդված

@hy

2007年の論文

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2007年学术文章

@wuu

2007年学术文章

@zh-cn

2007年学术文章

@zh-hans

2007年学术文章

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2007年学术文章

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2007年學術文章

@yue

name

High-affinity single-domain binding proteins with a binary-code interface

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High-affinity single-domain binding proteins with a binary-code interface

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High-affinity single-domain binding proteins with a binary-code interface

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type

label

High-affinity single-domain binding proteins with a binary-code interface

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High-affinity single-domain binding proteins with a binary-code interface

@en

High-affinity single-domain binding proteins with a binary-code interface

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prefLabel

High-affinity single-domain binding proteins with a binary-code interface

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High-affinity single-domain binding proteins with a binary-code interface

@en

High-affinity single-domain binding proteins with a binary-code interface

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P2860

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P356

PNAS.0700149104

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

High-affinity single-domain binding proteins with a binary-code interface

@en

P2093

Akiko Koide

http://www.w3.org/2001/XMLSchema#string

Kaori Esaki

http://www.w3.org/2001/XMLSchema#string

Ryan N Gilbreth

http://www.w3.org/2001/XMLSchema#string

P2860

The three-dimensional structure of the tenth type III module of fibronectin: an insight into RGD-mediated interactions

3D domain swapping: as domains continue to swap

A single-domain antibody fragment in complex with RNase A: non-canonical loop structures and nanomolar affinity using two CDR loops

Probing protein conformational changes in living cells by using designer binding proteins: application to the estrogen receptor.

Principles of protein-protein interactions

Shape complementarity at protein/protein interfaces

The atomic structure of protein-protein recognition sites

High-affinity binders selected from designed ankyrin repeat protein libraries

Anatomy of hot spots in protein interfaces

Expressed murine and human CDR-H3 intervals of equal length exhibit distinct repertoires that differ in their amino acid composition and predicted range of structures.

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6632-7

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scholarly article

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3820207

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10.1073/PNAS.0700149104

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P433

16

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P478

104

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P50

Valentina Tereshko

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2007-04-17T00:00:00Z

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6403179

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17420456

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1871837

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