Structural and Functional Insights into the Molecular Mechanisms Responsible for the Regulation of Pyruvate Dehydrogenase Kinase 2

Structural and Functional Insights into the Molecular Mechanisms Responsible for the Regulation of Pyruvate Dehydrogenase Kinase 2

Item
http://www.wikidata.org/entity/Q27650224
Pyruvate dehydrogenase kinase-4 structures reveal a metastable open conformation fostering robust core-free basal activityPivotal role of the C-terminal DW-motif in mediating inhibition of pyruvate dehydrogenase kinase 2 by dichloroacetateInhibitor-bound structures of human pyruvate dehydrogenase kinase 4Structure-guided Development of Specific Pyruvate Dehydrogenase Kinase Inhibitors Targeting the ATP-binding PocketInactivation of pyruvate dehydrogenase kinase 2 by mitochondrial reactive oxygen speciesThe pyruvate dehydrogenase complexes: structure-based function and regulation.Regulation of pyruvate metabolism and human diseaseA pH-dependent kinetic model of dihydrolipoamide dehydrogenase from multiple organisms.Elucidation of the interaction loci of the human pyruvate dehydrogenase complex E2·E3BP core with pyruvate dehydrogenase kinase 1 and kinase 2 by H/D exchange mass spectrometry and nuclear magnetic resonanceGlobal Kinetic Analysis of Mammalian E3 Reveals pH-dependent NAD+/NADH Regulation, Physiological Kinetic Reversibility, and Catalytic OptimumGlobal view of cognate kinase activation by the human pyruvate dehydrogenase complex.Comparative homology modeling of pyruvate dehydrogenase kinase isozymes from Xenopus tropicalis reveals structural basis for their subfunctionalization.Therapeutic Targeting of the Pyruvate Dehydrogenase Complex/Pyruvate Dehydrogenase Kinase (PDC/PDK) Axis in Cancer.The Pyruvate Dehydrogenase Complex and Related Assemblies in Health and Disease.
P2860

Structural and Functional Insights into the Molecular Mechanisms Responsible for the Regulation of Pyruvate Dehydrogenase Kinase 2

Item
http://www.wikidata.org/entity/Q27650224
description
2008 nî lūn-bûn
@nan
2008 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2008年の論文
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2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
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name
Structural and Functional Insi ...... yruvate Dehydrogenase Kinase 2
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Structural and Functional Insi ...... yruvate Dehydrogenase Kinase 2
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Structural and Functional Insi ...... yruvate Dehydrogenase Kinase 2
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Structural and Functional Insi ...... yruvate Dehydrogenase Kinase 2
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Structural and Functional Insi ...... yruvate Dehydrogenase Kinase 2
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Structural and Functional Insi ...... yruvate Dehydrogenase Kinase 2
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Structural and Functional Insi ...... yruvate Dehydrogenase Kinase 2
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Structural and Functional Insi ...... yruvate Dehydrogenase Kinase 2
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Structural and Functional Insi ...... yruvate Dehydrogenase Kinase 2
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P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P698
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P932
P356
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Structural and Functional Insi ...... yruvate Dehydrogenase Kinase 2
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P698
P921
P932