Mutations Outside the Anisomycin-Binding Site Can Make Ribosomes Drug-Resistant
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Potential key bases of ribosomal RNA to kingdom-specific spectra of antibiotic susceptibility and the possible archaeal origin of eukaryotesThe oxazolidinone antibiotics perturb the ribosomal peptidyl-transferase center and effect tRNA positioningGenome sequencing of linezolid-resistant Streptococcus pneumoniae mutants reveals novel mechanisms of resistanceRibosomal Antibiotics: Contemporary ChallengesThe Kink Turn, a Key Architectural Element in RNA StructureU2504 Determines the Species Specificity of the A-Site Cleft Antibiotics:Structures of Triacetyloleandomycin and Mycalamide A Bind to the Large Ribosomal Subunit of Haloarcula marismortuiStructures of the Escherichia coli ribosome with antibiotics bound near the peptidyl transferase center explain spectra of drug actionRevisiting the structures of several antibiotics bound to the bacterial ribosomeRNA Tertiary Interactions in a Riboswitch Stabilize the Structure of a Kink TurnCryo-EM Structure of the Archaeal 50S Ribosomal Subunit in Complex with Initiation Factor 6 and Implications for Ribosome EvolutionMolecular basis for erythromycin-dependent ribosome stalling during translation of the ErmBL leader peptideRevisiting the Haloarcula marismortui 50S ribosomal subunit modelYeast ribosomal protein L10 helps coordinate tRNA movement through the large subunit.Identification of distinct thiopeptide-antibiotic precursor lead compounds using translation machinery assaysCritical 23S rRNA interactions for macrolide-dependent ribosome stalling on the ErmCL nascent peptide chain.Structural analysis of base substitutions in Thermus thermophilus 16S rRNA conferring streptomycin resistance.A structural database for k-turn motifs in RNA.The key function of a conserved and modified rRNA residue in the ribosomal response to the nascent peptide.Mutations in 23S rRNA at the peptidyl transferase center and their relationship to linezolid binding and cross-resistance.The roles of RNA in the synthesis of protein.Hydroxylated histidine of human ribosomal protein uL2 is involved in maintaining the local structure of 28S rRNA in the ribosomal peptidyl transferase center.Neutrons, magnets, and photons: a career in structural biology.Inhibition of translation initiation complex formation by GE81112 unravels a 16S rRNA structural switch involved in P-site decoding.Resistance mutations generate divergent antibiotic susceptibility profiles against translation inhibitorsArchaeal aminoacyl-tRNA synthetases interact with the ribosome to recycle tRNAs.The 2009 Nobel Prize in Chemistry: Thomas A. Steitz and the structure of the ribosome.Elements of ribosomal drug resistance and specificity.Methylation of ribosomal protein L42 regulates ribosomal function and stress-adapted cell growth.A quasi-cyclic RNA nano-scale molecular object constructed using kink turnsMeasurement of average decoding rates of the 61 sense codons in vivo.Structure of a highly acidic β-lactamase from the moderate halophile Chromohalobacter sp. 560 and the discovery of a Cs(+)-selective binding site.A collection of caged compounds for probing roles of local translation in neurobiology.NMR characterisation of a highly conserved secondary structural RNA motif of Halobacterium halobium 23S rRNA.Small interfering RNA-mediated translation repression alters ribosome sensitivity to inhibition by cycloheximide in Chlamydomonas reinhardtii.RNAfitme: a webserver for modeling nucleobase and nucleoside residue conformation in fixed-backbone RNA structures
P2860
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P2860
Mutations Outside the Anisomycin-Binding Site Can Make Ribosomes Drug-Resistant
description
2008 nî lūn-bûn
@nan
2008 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Mutations Outside the Anisomycin-Binding Site Can Make Ribosomes Drug-Resistant
@ast
Mutations Outside the Anisomycin-Binding Site Can Make Ribosomes Drug-Resistant
@en
Mutations Outside the Anisomycin-Binding Site Can Make Ribosomes Drug-Resistant
@nl
type
label
Mutations Outside the Anisomycin-Binding Site Can Make Ribosomes Drug-Resistant
@ast
Mutations Outside the Anisomycin-Binding Site Can Make Ribosomes Drug-Resistant
@en
Mutations Outside the Anisomycin-Binding Site Can Make Ribosomes Drug-Resistant
@nl
prefLabel
Mutations Outside the Anisomycin-Binding Site Can Make Ribosomes Drug-Resistant
@ast
Mutations Outside the Anisomycin-Binding Site Can Make Ribosomes Drug-Resistant
@en
Mutations Outside the Anisomycin-Binding Site Can Make Ribosomes Drug-Resistant
@nl
P2093
P2860
P3181
P1476
Mutations Outside the Anisomycin-Binding Site Can Make Ribosomes Drug-Resistant
@en
P2093
Gregor Blaha
Güliz Gürel
Peter B Moore
Susan J Schroeder
Thomas A Steitz
P2860
P304
P3181
P356
10.1016/J.JMB.2008.03.075
P407
P577
2008-06-06T00:00:00Z