Crystal structure of the NEMO ubiquitin-binding domain in complex with Lys 63-linked di-ubiquitin
about
Two-sided ubiquitin binding explains specificity of the TAB2 NZF domainLinear ubiquitination signals in adaptive immune responsesSuper-resolution microscopy reveals a preformed NEMO lattice structure that is collapsed in incontinentia pigmentiSpecific recognition of linear polyubiquitin by A20 zinc finger 7 is involved in NF-κB regulationMolecular basis for specificity of the Met1-linked polyubiquitin signalLinear ubiquitination in immunityRecent advances in polyubiquitin chain recognition.NF-κB essential modulator (NEMO) interaction with linear and lys-63 ubiquitin chains contributes to NF-κB activationConstructing and decoding unconventional ubiquitin chains.Mechanisms of generating polyubiquitin chains of different topology.Covalent modification of the NF-κB essential modulator (NEMO) by a chemical compound can regulate its ubiquitin binding properties in vitro.Nuclear initiated NF-κB signaling: NEMO and ATM take center stage.Comparison of native and non-native ubiquitin oligomers reveals analogous structures and reactivities.Lys63-linked ubiquitin chain adopts multiple conformational states for specific target recognitionInhibition of Canonical NF-κB Signaling by a Small Molecule Targeting NEMO-Ubiquitin InteractionA20/TNFAIP3 inhibits NF-κB activation induced by the Kaposi's sarcoma-associated herpesvirus vFLIP oncoprotein.Molecular basis of NF-κB signalingStructural basis of signal transduction in the TNF receptor superfamilyMultitasking with ubiquitin through multivalent interactions.Structural studies of NF-κB signaling.Structural insights into the assembly of large oligomeric signalosomes in the Toll-like receptor-interleukin-1 receptor superfamilyDisulfide-mediated stabilization of the IκB kinase binding domain of NF-κB essential modulator (NEMO).Linear polyubiquitin chains: a new modifier involved in NFκB activation and chronic inflammation, including dermatitis.Mutation of nonessential cysteines shows that the NF-κB essential modulator forms a constitutive noncovalent dimer that binds IκB kinase-β with high affinity.Linear ubiquitination is involved in the pathogenesis of optineurin-associated amyotrophic lateral sclerosis.Coiled-coils: The long and short of it.Evidence for M1-Linked Polyubiquitin-Mediated Conformational Change in NEMO.Structural insights into the ubiquitin recognition by OPTN (optineurin) and its regulation by TBK1-mediated phosphorylation.RNA sensor LGP2 inhibits TRAF ubiquitin ligase to negatively regulate innate immune signaling.Tumor Necrosis Factor Receptor-Associated Factor Regulation of Nuclear Factor κB and Mitogen-Activated Protein Kinase Pathways
P2860
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P2860
Crystal structure of the NEMO ubiquitin-binding domain in complex with Lys 63-linked di-ubiquitin
description
2009 nî lūn-bûn
@nan
2009 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Crystal structure of the NEMO ...... ith Lys 63-linked di-ubiquitin
@ast
Crystal structure of the NEMO ...... ith Lys 63-linked di-ubiquitin
@en
Crystal structure of the NEMO ...... ith Lys 63-linked di-ubiquitin
@nl
type
label
Crystal structure of the NEMO ...... ith Lys 63-linked di-ubiquitin
@ast
Crystal structure of the NEMO ...... ith Lys 63-linked di-ubiquitin
@en
Crystal structure of the NEMO ...... ith Lys 63-linked di-ubiquitin
@nl
prefLabel
Crystal structure of the NEMO ...... ith Lys 63-linked di-ubiquitin
@ast
Crystal structure of the NEMO ...... ith Lys 63-linked di-ubiquitin
@en
Crystal structure of the NEMO ...... ith Lys 63-linked di-ubiquitin
@nl
P2093
P2860
P3181
P1433
P1476
Crystal structure of the NEMO ...... ith Lys 63-linked di-ubiquitin
@en
P2093
Atsushi Yamagata
Azusa Yoshikawa
Hisatoshi Mimura
Masami Yamashita
Shuya Fukai
Yusuke Sato
P2860
P304
P3181
P356
10.1016/J.FEBSLET.2009.09.028
P407
P577
2009-10-20T00:00:00Z