Specific recognition of linear polyubiquitin by A20 zinc finger 7 is involved in NF-κB regulation - Test2 - elhamkhani - TriplyDB

Specific recognition of linear polyubiquitin by A20 zinc finger 7 is involved in NF-κB regulation

Specific recognition of linear polyubiquitin by A20 zinc finger 7 is involved in NF-κB regulation

http://www.wikidata.org/entity/Q27674024

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Ubiquitin modifications TNF biology, pathogenic mechanisms and emerging therapeutic strategies Regulation of Met1-linked polyubiquitin signalling by the deubiquitinase OTULIN Regulation of nuclear factor-κB in autoimmunity Deconstructing innate immune signaling in myelodysplastic syndromes The TLR and IL-1 signalling network at a glance Regulation of NF-κB by ubiquitination Linear ubiquitination signals in adaptive immune responses Structural and Functional Analyses of DNA-Sensing and Immune Activation by Human cGAS New conformations of linear polyubiquitin chains from crystallographic and solution-scattering studies expand the conformational space of polyubiquitin A novel mode of ubiquitin recognition by the ubiquitin-binding zinc finger domain of WRNIP1 Molecular basis for specificity of the Met1-linked polyubiquitin signal Linear ubiquitination in immunity The seventh zinc finger motif of A20 is required for the suppression of TNF-α-induced apoptosis The linear ubiquitin assembly complex (LUBAC) is essential for NLRP3 inflammasome activation.The linear ubiquitin chain assembly complex regulates TRAIL-induced gene activation and cell death.Protein ubiquitination in lymphoid malignancies.Phenotypic complementation of genetic immunodeficiency by chronic herpesvirus infection.UBE2L3 polymorphism amplifies NF-κB activation and promotes plasma cell development, linking linear ubiquitination to multiple autoimmune diseases.A20 suppresses vascular inflammation by recruiting proinflammatory signaling molecules to intracellular aggresomes Structural basis for ubiquitin recognition by ubiquitin-binding zinc finger of FAAP20.The ubiquitin-modifying enzyme A20 restricts ubiquitination of the kinase RIPK3 and protects cells from necroptosis A20: linking a complex regulator of ubiquitylation to immunity and human disease Involvement of A20 in the molecular switch that activates the non-canonical NF-кB pathway Two phases of inflammatory mediator production defined by the study of IRAK2 and IRAK1 knock-in mice.Linear ubiquitination by LUBEL has a role in Drosophila heat stress response.Porcine Reproductive and Respiratory Syndrome Virus nsp1α Inhibits NF-κB Activation by Targeting the Linear Ubiquitin Chain Assembly Complex.Consequences of the recurrent MYD88(L265P) somatic mutation for B cell tolerance.Distinct phylogenetic relationships and biochemical properties of Arabidopsis ovarian tumor-related deubiquitinases support their functional differentiation.Essential role of the linear ubiquitin chain assembly complex in lymphoma revealed by rare germline polymorphisms.Linear ubiquitination-mediated NF-κB regulation and its related disorders.Molecular control of the NEMO family of ubiquitin-binding proteins.NF-κB and Rheumatoid Arthritis: Will Understanding Genetic Risk Lead to a Therapeutic Reward?Immune diseases caused by mutations in kinases and components of the ubiquitin system.Regulation of NF-κB by TNF family cytokines.Ubiquitin-binding domains: mechanisms of ubiquitin recognition and use as tools to investigate ubiquitin-modified proteomes.Induction of the inflammatory regulator A20 by gibberellic acid in airway epithelial cells.Deubiquitinases and the new therapeutic opportunities offered to cancer.DUBs, the regulation of cell identity and disease.Roles of linear ubiquitinylation, a crucial regulator of NF-κB and cell death, in the immune system.

P2860

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P2860

Specific recognition of linear polyubiquitin by A20 zinc finger 7 is involved in NF-κB regulation

http://www.wikidata.org/entity/Q27674024

description

2012 nî lūn-bûn

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2012 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2012 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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Specific recognition of linear ...... s involved in NF-κB regulation

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Specific recognition of linear ...... s involved in NF-κB regulation

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Specific recognition of linear ...... s involved in NF-κB regulation

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Specific recognition of linear ...... s involved in NF-κB regulation

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Specific recognition of linear ...... s involved in NF-κB regulation

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Specific recognition of linear ...... s involved in NF-κB regulation

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Specific recognition of linear ...... s involved in NF-κB regulation

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Specific recognition of linear ...... s involved in NF-κB regulation

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Specific recognition of linear ...... s involved in NF-κB regulation

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P1433

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P1433

The EMBO Journal

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Specific recognition of linear ...... s involved in NF-κB regulation

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P2093

Averil Ma

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Eiji Goto

http://www.w3.org/2001/XMLSchema#string

Hiroshi Nishimasu

http://www.w3.org/2001/XMLSchema#string

Kiyoko Kamei

http://www.w3.org/2001/XMLSchema#string

Osamu Nureki

http://www.w3.org/2001/XMLSchema#string

Ryuichiro Ishitani

http://www.w3.org/2001/XMLSchema#string

P2860

Finding NEMO by K63-linked polyubiquitin chain

TAK1 is a ubiquitin-dependent kinase of MKK and IKK

Linear ubiquitination prevents inflammation and regulates immune signalling

SHARPIN is a component of the NF-κB-activating linear ubiquitin chain assembly complex

SHARPIN forms a linear ubiquitin ligase complex regulating NF-κB activity and apoptosis

De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-kappaB signalling

A ubiquitin ligase complex assembles linear polyubiquitin chains

Inflammatory cardiac valvulitis in TAX1BP1-deficient mice through selective NF-kappaB activation

Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes

The ubiquitin-editing enzyme A20 requires RNF11 to downregulate NF-kappaB signalling

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3856-3870

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scholarly article

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2013578

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10.1038/EMBOJ.2012.241

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P433

19

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31

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Fuminori Tokunaga

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2012-08-28T00:00:00Z

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231861794

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23032187

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3463848

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