Skepinone-L is a selective p38 mitogen-activated protein kinase inhibitor
about
Skeletal muscle wasting and renewal: a pivotal role of myokine IL-6A p38 substrate-specific MK2-EGFP translocation assay for identification and validation of new p38 inhibitors in living cells: a comprising alternative for acquisition of cellular p38 inhibition dataIL-13-induced airway mucus production is attenuated by MAPK13 inhibition.Mechanism and consequence of the autoactivation of p38α mitogen-activated protein kinase promoted by TAB1Microtubules Inhibit E-Cadherin Adhesive Activity by Maintaining Phosphorylated p120-Catenin in a Colon Carcinoma Cell Model.Spinal inhibition of p38 MAP kinase reduces inflammatory and neuropathic pain in male but not female mice: Sex-dependent microglial signaling in the spinal cord.Halogen-enriched fragment libraries as chemical probes for harnessing halogen bonding in fragment-based lead discovery.In vivo RNAi screening identifies a mechanism of sorafenib resistance in liver cancer.The ins and outs of selective kinase inhibitor development.Arachidonoyl-phosphatidylcholine oscillates during the cell cycle and counteracts proliferation by suppressing Akt membrane binding.Mitogen-activated protein kinases as therapeutic targets for rheumatoid arthritis.A Comprehensive Structural Overview of p38α MAPK in Complex with Type I Inhibitors.Review structure- and dynamics-based computational design of anticancer drugs.C3 exoenzyme impairs cell proliferation and apoptosis by altering the activity of transcription factors.First comprehensive structural and biophysical analysis of MAPK13 inhibitors targeting DFG-in and DFG-out binding modes.The crystal structure of phosphorylated MAPK13 reveals common structural features and differences in p38 MAPK family activation.Unprecedently Large-Scale Kinase Inhibitor Set Enabling the Accurate Prediction of Compound-Kinase Activities: A Way toward Selective Promiscuity by Design?A public-private partnership to unlock the untargeted kinome.Biological evaluation of benzosuberones.Recent Advances in the Inhibition of p38 MAPK as a Potential Strategy for the Treatment of Alzheimer's Disease.A Chemical Probe Strategy for Interrogating Inhibitor Selectivity Across the MEK Kinase Family.Optimized Target Residence Time: Type I1/2 Inhibitors for p38α MAP Kinase with Improved Binding Kinetics through Direct Interaction with the R-Spine.Anti-inflammatory and anti-proliferative effects of CBS3830 in arterialized vein grafts in rats.Data-Driven Exploration of Selectivity and Off-Target Activities of Designated Chemical Probes
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P2860
Skepinone-L is a selective p38 mitogen-activated protein kinase inhibitor
description
2011 nî lūn-bûn
@nan
2011 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Skepinone-L is a selective p38 mitogen-activated protein kinase inhibitor
@ast
Skepinone-L is a selective p38 mitogen-activated protein kinase inhibitor
@en
Skepinone-L is a selective p38 mitogen-activated protein kinase inhibitor
@nl
type
label
Skepinone-L is a selective p38 mitogen-activated protein kinase inhibitor
@ast
Skepinone-L is a selective p38 mitogen-activated protein kinase inhibitor
@en
Skepinone-L is a selective p38 mitogen-activated protein kinase inhibitor
@nl
prefLabel
Skepinone-L is a selective p38 mitogen-activated protein kinase inhibitor
@ast
Skepinone-L is a selective p38 mitogen-activated protein kinase inhibitor
@en
Skepinone-L is a selective p38 mitogen-activated protein kinase inhibitor
@nl
P2093
P2860
P50
P3181
P356
P1476
Skepinone-L is a selective p38 mitogen-activated protein kinase inhibitor
@en
P2093
Christian Grütter
Daniel Rauh
Johannes Romir
Solveigh C Koeberle
Stefan A Laufer
Stefan Fischer
Verena Schattel
Wolfgang Albrecht
P2860
P2888
P3181
P356
10.1038/NCHEMBIO.761
P577
2011-12-25T00:00:00Z
P6179
1008201399