Skepinone-L is a selective p38 mitogen-activated protein kinase inhibitor - Test2 - elhamkhani - TriplyDB

Skepinone-L is a selective p38 mitogen-activated protein kinase inhibitor

Skepinone-L is a selective p38 mitogen-activated protein kinase inhibitor

http://www.wikidata.org/entity/Q27676453

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Skeletal muscle wasting and renewal: a pivotal role of myokine IL-6 A p38 substrate-specific MK2-EGFP translocation assay for identification and validation of new p38 inhibitors in living cells: a comprising alternative for acquisition of cellular p38 inhibition data IL-13-induced airway mucus production is attenuated by MAPK13 inhibition.Mechanism and consequence of the autoactivation of p38α mitogen-activated protein kinase promoted by TAB1 Microtubules Inhibit E-Cadherin Adhesive Activity by Maintaining Phosphorylated p120-Catenin in a Colon Carcinoma Cell Model.Spinal inhibition of p38 MAP kinase reduces inflammatory and neuropathic pain in male but not female mice: Sex-dependent microglial signaling in the spinal cord.Halogen-enriched fragment libraries as chemical probes for harnessing halogen bonding in fragment-based lead discovery.In vivo RNAi screening identifies a mechanism of sorafenib resistance in liver cancer.The ins and outs of selective kinase inhibitor development.Arachidonoyl-phosphatidylcholine oscillates during the cell cycle and counteracts proliferation by suppressing Akt membrane binding.Mitogen-activated protein kinases as therapeutic targets for rheumatoid arthritis.A Comprehensive Structural Overview of p38α MAPK in Complex with Type I Inhibitors.Review structure- and dynamics-based computational design of anticancer drugs.C3 exoenzyme impairs cell proliferation and apoptosis by altering the activity of transcription factors.First comprehensive structural and biophysical analysis of MAPK13 inhibitors targeting DFG-in and DFG-out binding modes.The crystal structure of phosphorylated MAPK13 reveals common structural features and differences in p38 MAPK family activation.Unprecedently Large-Scale Kinase Inhibitor Set Enabling the Accurate Prediction of Compound-Kinase Activities: A Way toward Selective Promiscuity by Design?A public-private partnership to unlock the untargeted kinome.Biological evaluation of benzosuberones.Recent Advances in the Inhibition of p38 MAPK as a Potential Strategy for the Treatment of Alzheimer's Disease.A Chemical Probe Strategy for Interrogating Inhibitor Selectivity Across the MEK Kinase Family.Optimized Target Residence Time: Type I1/2 Inhibitors for p38α MAP Kinase with Improved Binding Kinetics through Direct Interaction with the R-Spine.Anti-inflammatory and anti-proliferative effects of CBS3830 in arterialized vein grafts in rats.Data-Driven Exploration of Selectivity and Off-Target Activities of Designated Chemical Probes

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P2860

Skepinone-L is a selective p38 mitogen-activated protein kinase inhibitor

http://www.wikidata.org/entity/Q27676453

description

2011 nî lūn-bûn

@nan

2011 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2011年の論文

@ja

2011年論文

@yue

2011年論文

@zh-hant

2011年論文

@zh-hk

2011年論文

@zh-mo

2011年論文

@zh-tw

2011年论文

@wuu

name

Skepinone-L is a selective p38 mitogen-activated protein kinase inhibitor

@ast

Skepinone-L is a selective p38 mitogen-activated protein kinase inhibitor

@en

Skepinone-L is a selective p38 mitogen-activated protein kinase inhibitor

@nl

type

label

Skepinone-L is a selective p38 mitogen-activated protein kinase inhibitor

@ast

Skepinone-L is a selective p38 mitogen-activated protein kinase inhibitor

@en

Skepinone-L is a selective p38 mitogen-activated protein kinase inhibitor

@nl

prefLabel

Skepinone-L is a selective p38 mitogen-activated protein kinase inhibitor

@ast

Skepinone-L is a selective p38 mitogen-activated protein kinase inhibitor

@en

Skepinone-L is a selective p38 mitogen-activated protein kinase inhibitor

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Nature Chemical Biology

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Skepinone-L is a selective p38 mitogen-activated protein kinase inhibitor

@en

P2093

Christian Grütter

http://www.w3.org/2001/XMLSchema#string

Daniel Rauh

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Johannes Romir

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Solveigh C Koeberle

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Stefan A Laufer

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Stefan Fischer

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Verena Schattel

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Wolfgang Albrecht

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P2860

The protein kinase complement of the human genome

Structural basis for p38alpha MAP kinase quinazolinone and pyridol-pyrimidine inhibitor specificity

A quantitative analysis of kinase inhibitor selectivity

Pathway to the clinic: inhibition of P38 MAP kinase. A review of ten chemotypes selected for development

Macrophage migration inhibitory factor elicits an angiogenic phenotype in human ectopic endometrial cells and triggers the production of major angiogenic factors via CD44, CD74, and MAPK signaling pathways

Pamapimod, a novel p38 mitogen-activated protein kinase inhibitor: preclinical analysis of efficacy and selectivity

Aza-analogue dibenzepinone scaffolds as p38 mitogen-activated protein kinase inhibitors: design, synthesis, and biological data of inhibitors with improved physicochemical properties.

Selective activation of the p38 MAPK pathway by synthetic monophosphoryl lipid A.

Interleukin (IL)-4 and IL-13 up-regulate monocyte chemoattractant protein-1 expression in human bronchial epithelial cells: involvement of p38 mitogen-activated protein kinase, extracellular signal-regulated kinase 1/2 and Janus kinase-2 but not c-J

Glycogen synthase kinase-3 and p38 MAPK are required for opioid-induced microglia apoptosis

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P304

141-3

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scholarly article

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1638977

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10.1038/NCHEMBIO.761

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P433

2

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P478

8

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Andreas Koeberle

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2011-12-25T00:00:00Z

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1008201399

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22198732

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