E2 enzyme inhibition by stabilization of a low-affinity interface with ubiquitin - Test2 - elhamkhani - TriplyDB

E2 enzyme inhibition by stabilization of a low-affinity interface with ubiquitin

E2 enzyme inhibition by stabilization of a low-affinity interface with ubiquitin

http://www.wikidata.org/entity/Q27680817

about

Structure of a RING E3 trapped in action reveals ligation mechanism for the ubiquitin-like protein NEDD8 E2 enzymes: more than just middle men Crystal Structure of a Ube2S-Ubiquitin Conjugate CLMSVault: A Software Suite for Protein Cross-Linking Mass-Spectrometry Data Analysis and Visualization.Pivotal role for the ubiquitin Y59-E51 loop in lysine 48 polyubiquitination.Targeting Cullin-RING E3 ubiquitin ligases for drug discovery: structure, assembly and small-molecule modulation.Targeting cullin-RING ligases for cancer treatment: rationales, advances and therapeutic implications.Sculpting the proteome with small molecules Alternative modulation of protein-protein interactions by small molecules E2 superfamily of ubiquitin-conjugating enzymes: constitutively active or activated through phosphorylation in the catalytic cleft.Suramin inhibits cullin-RING E3 ubiquitin ligases.Insights Into the Allosteric Inhibition of the SUMO E2 Enzyme Ubc9.Multimodal mechanism of action for the Cdc34 acidic loop: a case study for why ubiquitin-conjugating enzymes have loops and tails The bacterial pathogen-ubiquitin interface: lessons learned from Shigella.SCF ubiquitin ligase-targeted therapies.Inhibitors of the Cdc34 acidic loop: A computational investigation integrating molecular dynamics, virtual screening and docking approaches.Mechanism of catalysis, E2 recognition, and autoinhibition for the IpaH family of bacterial E3 ubiquitin ligases.Mechanism of Lysine 48 Selectivity during Polyubiquitin Chain Formation by the Ube2R1/2 Ubiquitin-Conjugating Enzyme.DNA damage: walking the edge.Stabilization of protein-protein interactions in drug discovery.Insights Into the Allosteric Inhibition of the SUMO E2 Enzyme Ubc9 Real-time tracking of complex ubiquitination cascades using a fluorescent confocal on-bead assay

P2860

Q24299638-9CD123B7-8D5E-461E-BC42-DBBFEEC134BC Q26752818-7D4FDAC8-1785-47E9-BF54-ECC5D54614A7 Q28553007-27041856-29CE-4046-8CDB-992F9AF0CF4A Q30402357-E950AB15-7820-4A7D-B91A-C38E6416A4B9 Q33767456-82BC32B5-C200-4CFB-AC24-F7E760413CCA Q34043797-0B8436A1-2861-43CC-9CC8-5F81C0B48C09 Q34043821-D58A0A04-7EB5-46C7-85DE-C97187294356 Q35344020-0492ECEB-A709-4D1C-80BB-EB1B78E2D37F Q35620999-26E51740-0CD0-4547-9835-9B17819617BB Q36158657-8200CB6F-EB54-4781-9361-DBB50D1F29F7 Q36802367-49EB1FB3-1F48-4A34-AA0A-4206B50CB6E8 Q37151638-9CFE41BC-A55F-4968-BB50-167B0A40130A Q37349016-567F94B1-75FC-42C8-B876-5472D33A892D Q38263749-FAE67C85-F306-407F-8D49-845636650C49 Q38267996-E2F79217-E0DD-418B-8DB2-A5640654C900 Q40466750-09300D56-AFD6-4DB3-B492-12137A54E7B1 Q42321764-4899C8AD-F775-4A58-9F00-40111E25F4A6 Q42406812-152CBDAA-9615-4410-B41A-C3614EAEC167 Q44593962-3E996C10-90C3-4F60-ADFA-7806B9732682 Q47938743-60F94825-52F6-4230-A140-D74389CC60E4 Q57807760-1442E411-E2B9-4E77-90E2-6D5C2381147C Q58791515-9ABE7CB0-C183-44CA-9E82-6897E80A0985

P2860

E2 enzyme inhibition by stabilization of a low-affinity interface with ubiquitin

http://www.wikidata.org/entity/Q27680817

description

2014 nî lūn-bûn

@nan

2014 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի փետրվարին հրատարակված գիտական հոդված

@hy

2014年の論文

@ja

2014年論文

@yue

2014年論文

@zh-hant

2014年論文

@zh-hk

2014年論文

@zh-mo

2014年論文

@zh-tw

2014年论文

@wuu

name

E2 enzyme inhibition by stabilization of a low-affinity interface with ubiquitin

@ast

E2 enzyme inhibition by stabilization of a low-affinity interface with ubiquitin

@en

E2 enzyme inhibition by stabilization of a low-affinity interface with ubiquitin

@nl

type

label

E2 enzyme inhibition by stabilization of a low-affinity interface with ubiquitin

@ast

E2 enzyme inhibition by stabilization of a low-affinity interface with ubiquitin

@en

E2 enzyme inhibition by stabilization of a low-affinity interface with ubiquitin

@nl

prefLabel

E2 enzyme inhibition by stabilization of a low-affinity interface with ubiquitin

@ast

E2 enzyme inhibition by stabilization of a low-affinity interface with ubiquitin

@en

E2 enzyme inhibition by stabilization of a low-affinity interface with ubiquitin

@nl

P1433

Q27680817-725DAEC9-B695-4943-911F-C68EE94DDAD0

P1476

Q27680817-990E956E-9176-4DB3-9B12-C3E5878AB748

P2093

Q27680817-2837D2BE-994D-4EB2-80BA-27ED9FB0DC36

Q27680817-2B06F551-B9CD-4A79-A54F-D3214C8A84B4

Q27680817-5415D7DD-86A0-4A3E-B6E8-CC4B5FA88EF5

Q27680817-5A9D9652-66CE-41F6-A5EB-5B33EE2D8913

Q27680817-6EB81C6C-894E-4046-A347-D2FBCB041B4C

Q27680817-7A18C804-6182-4776-890A-AAE1C56A4C08

Q27680817-8714E332-4A46-4E62-BFC5-1E6440A1B10C

Q27680817-A3EF951A-993B-4877-89F0-4E08A077DD10

Q27680817-D6919B36-1F3E-4FAE-B79D-978FC860975B

Q27680817-EAFEC4AC-4664-4411-A7B8-36D14F1733A4

P2860

Q27680817-00A04D46-F304-4FB8-A402-25DAB5EE50FA

Q27680817-00D916E1-E81A-42F7-BF7E-CF1C034D8A0C

Q27680817-03D91BEC-E589-4E96-984E-BA8FDB3C026D

Q27680817-077C46C3-7E12-4F60-8072-D23B00F84E67

Q27680817-0D3EDE0E-A72B-49A4-B92B-37A46B9497C2

Q27680817-0E040AE4-0CDE-4775-9B1A-61A9F37CF250

Q27680817-1023FEA5-1A75-4D58-98A4-2BDDB850810F

Q27680817-15D3130B-E490-40F4-9304-E5A440D50B9D

Q27680817-19DBD884-1912-4C28-9437-90D2B7396EC5

Q27680817-1E4EAC3B-4EC4-4EE8-9F3A-B19BA0392445

P2888

Q27680817-EDB483B8-C5EF-4061-BD2F-C08B67B606EC

P304

Q27680817-034C2FA5-13AA-4172-A4A2-B59F8A4B1B3F

P31

Q27680817-BD75FB4D-D637-4D8C-ADDA-D73AEB1D94BF

P3181

Q27680817-5EBF47AF-4D5A-4D5F-AFEC-CB17D26B3D41

P356

Q27680817-22106B14-7354-4A65-B063-F9A3205D071C

P433

Q27680817-7F6629A4-F31E-45FB-B1E8-65C6C1630765

P478

Q27680817-B23AE2BB-A09B-4385-8CFB-EF83DFB87B6C

P50

Q27680817-6F677F96-86F3-4528-A5B4-0E351CB1E18A

Q27680817-82E9323C-04BA-4634-919F-9A662E0949AF

Q27680817-FF1D5CAB-C926-49F1-9463-F3B8766D0FA9

P577

Q27680817-40DB23FA-F89B-4B96-9D80-F950B0A28C11

P5875

Q27680817-BB2BDD86-24B6-4B33-99FF-48500AE3EBA0

P6179

Q27680817-39D04AC7-EA29-43C7-B40B-341A1F3EDC80

P698

Q27680817-1947D200-E263-4EA0-888F-8784AD495517

P921

Q27680817-9ADC0A91-86B5-4865-9F4A-77ED7EADAA6A

P932

Q27680817-8EA4F244-AB49-4795-AF1F-9931E34677FB

P3181

P356

P1433

Nature Chemical Biology

P1476

E2 enzyme inhibition by stabilization of a low-affinity interface with ubiquitin

@en

P2093

Amy Ziemba

http://www.w3.org/2001/XMLSchema#string

Anne Marinier

http://www.w3.org/2001/XMLSchema#string

Frank Sicheri

http://www.w3.org/2001/XMLSchema#string

Gary Kleiger

http://www.w3.org/2001/XMLSchema#string

Hao Huang

http://www.w3.org/2001/XMLSchema#string

Mike Tyers

http://www.w3.org/2001/XMLSchema#string

Pankaj Garg

http://www.w3.org/2001/XMLSchema#string

Sachdev Sidhu

http://www.w3.org/2001/XMLSchema#string

Serge Plamondon

http://www.w3.org/2001/XMLSchema#string

Stephen Orlicky

http://www.w3.org/2001/XMLSchema#string

P2860

The mechanism of linkage-specific ubiquitin chain elongation by a single-subunit E2

Noncovalent interaction between Ubc9 and SUMO promotes SUMO chain formation

Structural insights into NEDD8 activation of cullin-RING ligases: conformational control of conjugation

Rapid E2-E3 assembly and disassembly enable processive ubiquitylation of cullin-RING ubiquitin ligase substrates

Cdc53/cullin and the essential Hrt1 RING-H2 subunit of SCF define a ubiquitin ligase module that activates the E2 enzyme Cdc34

Regulation and cellular roles of ubiquitin-specific deubiquitinating enzymes

Ubiquitin-like protein activation by E1 enzymes: the apex for downstream signalling pathways

Processing of X-ray diffraction data collected in oscillation mode

Structure of a c-Cbl-UbcH7 complex: RING domain function in ubiquitin-protein ligases

Structure of a conjugating enzyme-ubiquitin thiolester intermediate reveals a novel role for the ubiquitin tail

P2888

P304

156-163

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P3181

5106373

http://www.w3.org/2001/XMLSchema#string

P356

10.1038/NCHEMBIO.1412

http://www.w3.org/2001/XMLSchema#string

P433

2

http://www.w3.org/2001/XMLSchema#string

P478

10

http://www.w3.org/2001/XMLSchema#string

P50

Derek F Ceccarelli

Daniel J St-Cyr

P577

2014-02-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

259246901

http://www.w3.org/2001/XMLSchema#string

P6179

1029586412

http://www.w3.org/2001/XMLSchema#string

P698

24316736

http://www.w3.org/2001/XMLSchema#string

P921

P932

3905752

http://www.w3.org/2001/XMLSchema#string