Cdc53/cullin and the essential Hrt1 RING-H2 subunit of SCF define a ubiquitin ligase module that activates the E2 enzyme Cdc34
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The regulation of cyclin D1 degradation: roles in cancer development and the potential for therapeutic inventionRING fingers mediate ubiquitin-conjugating enzyme (E2)-dependent ubiquitinationStem-loop binding protein, the protein that binds the 3' end of histone mRNA, is cell cycle regulated by both translational and posttranslational mechanismsThe RING-H2 finger protein APC11 and the E2 enzyme UBC4 are sufficient to ubiquitinate substrates of the anaphase-promoting complexFeatures of the parkin/ariadne-like ubiquitin ligase, HHARI, that regulate its interaction with the ubiquitin-conjugating enzyme, Ubch7UV-damaged DNA-binding proteins are targets of CUL-4A-mediated ubiquitination and degradationAPC2 Cullin protein and APC11 RING protein comprise the minimal ubiquitin ligase module of the anaphase-promoting complexTIP120A associates with cullins and modulates ubiquitin ligase activityCdc123 and checkpoint forkhead associated with RING proteins control the cell cycle by controlling eIF2gamma abundanceSCFbeta-TRCP controls clock-dependent transcription via casein kinase 1-dependent degradation of the mammalian period-1 (Per1) proteinRiplet/RNF135, a RING finger protein, ubiquitinates RIG-I to promote interferon-beta induction during the early phase of viral infectionE2-RING expansion of the NEDD8 cascade confers specificity to cullin modificationControl of rapsyn stability by the CUL-3-containing E3 ligase complexVHL-box and SOCS-box domains determine binding specificity for Cul2-Rbx1 and Cul5-Rbx2 modules of ubiquitin ligasesCUL7: A DOC domain-containing cullin selectively binds Skp1.Fbx29 to form an SCF-like complex.NARF, an nemo-like kinase (NLK)-associated ring finger protein regulates the ubiquitylation and degradation of T cell factor/lymphoid enhancer factor (TCF/LEF)Phosphorylation-dependent degradation of c-Myc is mediated by the F-box protein Fbw7Proximity-induced activation of human Cdc34 through heterologous dimerization.Analysis of the adenovirus E1B-55K-anchored proteome reveals its link to ubiquitination machinery.The CUL1 C-terminal sequence and ROC1 are required for efficient nuclear accumulation, NEDD8 modification, and ubiquitin ligase activity of CUL1Nedd8 modification of cul-1 activates SCF(beta(TrCP))-dependent ubiquitination of IkappaBalphaBTB protein Keap1 targets antioxidant transcription factor Nrf2 for ubiquitination by the Cullin 3-Roc1 ligaseThe Rbx1 subunit of SCF and VHL E3 ubiquitin ligase activates Rub1 modification of cullins Cdc53 and Cul2Ligand-dependent degradation of Smad3 by a ubiquitin ligase complex of ROC1 and associated proteinsThe checkpoint protein Chfr is a ligase that ubiquitinates Plk1 and inhibits Cdc2 at the G2 to M transition.Identification of the von Hippel-lindau tumor-suppressor protein as part of an active E3 ubiquitin ligase complexActivation of HIF1alpha ubiquitination by a reconstituted von Hippel-Lindau (VHL) tumor suppressor complexPseudosubstrate regulation of the SCF(beta-TrCP) ubiquitin ligase by hnRNP-UTargeted disruption of p185/Cul7 gene results in abnormal vascular morphogenesisThe Cullin3 ubiquitin ligase functions as a Nedd8-bound heterodimerThe fission yeast COP9/signalosome is involved in cullin modification by ubiquitin-related Ned8pInvolvement of an SCFSlmb complex in timely elimination of E2F upon initiation of DNA replication in DrosophilaCombinatorial diversity of fission yeast SCF ubiquitin ligases by homo- and heterooligomeric assemblies of the F-box proteins Pop1p and Pop2p.Genetically engineered mouse models for functional studies of SKP1-CUL1-F-box-protein (SCF) E3 ubiquitin ligasesMutations in the Hydrophobic Core of Ubiquitin Differentially Affect Its Recognition by Receptor ProteinsStructures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin LigasesA Dual E3 Mechanism for Rub1 Ligation to Cdc53Structure of a Glomulin-RBX1-CUL1 Complex: Inhibition of a RING E3 Ligase through Masking of Its E2-Binding SurfaceStructural Conservation of Distinctive N-terminal Acetylation-Dependent Interactions across a Family of Mammalian NEDD8 Ligation EnzymesE2 enzyme inhibition by stabilization of a low-affinity interface with ubiquitin
P2860
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P2860
Cdc53/cullin and the essential Hrt1 RING-H2 subunit of SCF define a ubiquitin ligase module that activates the E2 enzyme Cdc34
description
1999 nî lūn-bûn
@nan
1999 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Cdc53/cullin and the essential ...... activates the E2 enzyme Cdc34
@ast
Cdc53/cullin and the essential ...... activates the E2 enzyme Cdc34
@en
Cdc53/cullin and the essential ...... activates the E2 enzyme Cdc34
@nl
type
label
Cdc53/cullin and the essential ...... activates the E2 enzyme Cdc34
@ast
Cdc53/cullin and the essential ...... activates the E2 enzyme Cdc34
@en
Cdc53/cullin and the essential ...... activates the E2 enzyme Cdc34
@nl
prefLabel
Cdc53/cullin and the essential ...... activates the E2 enzyme Cdc34
@ast
Cdc53/cullin and the essential ...... activates the E2 enzyme Cdc34
@en
Cdc53/cullin and the essential ...... activates the E2 enzyme Cdc34
@nl
P2093
P2860
P356
P1433
P1476
Cdc53/cullin and the essential ...... activates the E2 enzyme Cdc34
@en
P2093
A Shevchenko
C C Correll
J Claypool
R J Deshaies
R M Feldman
S Sandmeyer
W Zachariae
P2860
P304
P356
10.1101/GAD.13.12.1614
P407
P50
P577
1999-06-15T00:00:00Z