Structure of the high affinity complex of inositol trisphosphate with a phospholipase C pleckstrin homology domain
about
Reconstruction of ancestral protein sequences and its applicationsPleckstrin 2, a widely expressed paralog of pleckstrin involved in actin rearrangementPleckstrin induces cytoskeletal reorganization via a Rac-dependent pathwayRegulation of Tiam1 nucleotide exchange activity by pleckstrin domain binding ligandsIdentification of pleckstrin-homology-domain-containing proteins with novel phosphoinositide-binding specificitiesMechanistic basis of differential cellular responses of phosphatidylinositol 3,4-bisphosphate- and phosphatidylinositol 3,4,5-trisphosphate-binding pleckstrin homology domainsAttenuation of cell adhesion in lymphocytes is regulated by CYTIP, a protein which mediates signal complex sequestrationNon-canonical interaction of phosphoinositides with pleckstrin homology domains of Tiam1 and ArhGAP9Structural basis for membrane targeting by the MVB12-associated β-prism domain of the human ESCRT-I MVB12 subunitAn alpha-helical extension of the ELMO1 pleckstrin homology domain mediates direct interaction to DOCK180 and is critical in Rac signalingNHE3 kinase A regulatory protein E3KARP binds the epithelial brush border Na+/H+ exchanger NHE3 and the cytoskeletal protein ezrinIdentification of a novel guanine nucleotide exchange factor for the Rho GTPasePleckstrin associates with plasma membranes and induces the formation of membrane projections: requirements for phosphorylation and the NH2-terminal PH domainA PH domain within OCRL bridges clathrin-mediated membrane trafficking to phosphoinositide metabolismSignal-dependent membrane targeting by pleckstrin homology (PH) domainsStructure of the PH domain and Btk motif from Bruton's tyrosine kinase: molecular explanations for X-linked agammaglobulinaemiaIdentification and analysis of PH domain-containing targets of phosphatidylinositol 3-kinase using a novel in vivo assay in yeast.The Gab1 PH domain is required for localization of Gab1 at sites of cell-cell contact and epithelial morphogenesis downstream from the met receptor tyrosine kinaseStructural basis of the membrane-targeting and unmasking mechanisms of the radixin FERM domainThe PH domain and the polybasic c domain of cytohesin-1 cooperate specifically in plasma membrane association and cellular functionVav2 is required for cell spreadingTruncation of C-mip (Tc-mip), a new proximal signaling protein, induces c-maf Th2 transcription factor and cytoskeleton reorganizationThe C2 domain calcium-binding motif: structural and functional diversityRegulated membrane localization of Tiam1, mediated by the NH2-terminal pleckstrin homology domain, is required for Rac-dependent membrane ruffling and C-Jun NH2-terminal kinase activationPhosphoinositides: tiny lipids with giant impact on cell regulationTurning off AKT: PHLPP as a drug targetPhosphoinositide binding by the SNX27 FERM domain regulates its localization at the immune synapse of activated T-cells.Computational studies of the binding profile of phosphoinositide PtdIns (3,4,5) P₃ with the pleckstrin homology domain of an oomycete cellulose synthaseStructure of a Ran-binding domain complexed with Ran bound to a GTP analogue: implications for nuclear transportCrystal structure of the pleckstrin homology-phosphotyrosine binding (PH-PTB) targeting region of insulin receptor substrate 1Crystal structure of the BEACH domain reveals an unusual fold and extensive association with a novel PH domainCrystal structures of the Dab homology domains of mouse disabled 1 and 2Structure of Galphaq-p63RhoGEF-RhoA complex reveals a pathway for the activation of RhoA by GPCRsGeneral and Versatile Autoinhibition of PLC IsozymesStructure-function study of the N-terminal domain of exocyst subunit Sec3Crystal structure of the yeast Sac1: implications for its phosphoinositide phosphatase functionThe Minimal Autoinhibited Unit of the Guanine Nucleotide Exchange Factor IntersectinZF21 Protein, a Regulator of the Disassembly of Focal Adhesions and Cancer Metastasis, Contains a Novel Noncanonical Pleckstrin Homology DomainMembrane Curvature Protein Exhibits Interdomain Flexibility and Binds a Small GTPaseStructural and Functional Characterization of the Kindlin-1 Pleckstrin Homology Domain
P2860
Q21283980-2617715F-83A2-41EE-B45C-C52E195F8227Q22010420-3DA1B274-EA7F-4BEB-A0BA-E8BFBB5D4A6FQ22010569-E3AAA604-2523-46FA-AE9B-BAB860EDA326Q22254209-2A819F2F-7D3B-43CB-A4BF-4F1102800317Q24290290-CF6A2E24-E619-4C69-A1D5-2F87967B98A1Q24292965-0654D348-ED0F-4905-9656-59504FB9B922Q24295854-E95771C5-842B-43E9-B010-3AF47DA854DDQ24299126-A634FA80-0B26-48EC-AC4F-388BB170C6E0Q24301573-59255099-63A3-46D0-83D2-F4610EF7786DQ24310171-F51459CA-9028-4CF8-8944-F4101B007EB0Q24315976-33456684-DB23-4E99-A5B7-8EB75BA46CB0Q24324614-3EA8B375-B2E1-4C0F-BF66-FFE02C2CBFDDQ24329139-CA7A88E2-AAE4-4AF8-BBB9-29DE0DC222E8Q24338714-12404153-D1E4-476E-A2EB-27EC44B08CBBQ24532099-9BC50703-3B44-4222-B134-8CB8D23CE579Q24532248-18EE0174-072E-464C-8288-A3AA17BA5ADBQ24533315-FEF26C43-0898-42A6-9D2B-3448111EDC47Q24554529-F8E88A36-5E9C-4A14-86AC-58C251EA7E49Q24598762-952EC95D-2D9D-48F8-94C9-EBA4B291FC87Q24647179-55A1E3D8-A837-4D08-9545-6F7B73D66C15Q24654126-A651DB6C-30D0-4941-9928-13B5DA41C62CQ24673065-4672360A-D512-494B-8F0D-B41AA605D9B8Q24674621-2FF19E86-1061-4120-86C9-38A25B686A24Q24678943-88DE0AAA-A797-4388-B4FF-1EEAA4A5E7A3Q27012953-72D884F0-4C0E-4369-9B94-75ECE3F9AE86Q27014094-9566E93B-66B9-4AFD-9AAE-1C48A8E626B9Q27342410-21815D33-9555-4771-B4AB-36FBB41164ABQ27350315-8A52A08B-F5C1-40FA-A0C5-E67D20B01156Q27617536-B353BA7D-144F-4E40-B439-D5AA51E8CCA2Q27619068-379175CF-9E4D-43D4-B1E0-A33FDCAD1802Q27639656-BDFAA1E9-3A26-4428-8916-26A4E2E732DBQ27641511-6273EC4E-73FE-4A3F-BCB7-699FD55A8F50Q27649382-7A49FA51-7130-4DEF-945A-F74D1E98E80EQ27651494-3241DF54-65EF-4872-B6BA-CB8B871DECC1Q27659629-8D5671D7-A144-48CB-9046-AD42F422B2E9Q27660521-966C7ACF-4D19-4CA2-A50F-FB2B825F2B36Q27662864-E162494E-4C74-4304-A4F6-747D4E99AFFCQ27670870-51965D31-DBC4-4D56-94B7-172CC3479D6FQ27674406-C18D341A-8639-41E7-A0C5-0AFAAB6E330AQ27675000-3152A550-3EB5-452B-84C2-B9A4FBFFB218
P2860
Structure of the high affinity complex of inositol trisphosphate with a phospholipase C pleckstrin homology domain
description
1995 nî lūn-bûn
@nan
1995 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
Structure of the high affinity ...... e C pleckstrin homology domain
@ast
Structure of the high affinity ...... e C pleckstrin homology domain
@en
Structure of the high affinity ...... e C pleckstrin homology domain
@nl
type
label
Structure of the high affinity ...... e C pleckstrin homology domain
@ast
Structure of the high affinity ...... e C pleckstrin homology domain
@en
Structure of the high affinity ...... e C pleckstrin homology domain
@nl
prefLabel
Structure of the high affinity ...... e C pleckstrin homology domain
@ast
Structure of the high affinity ...... e C pleckstrin homology domain
@en
Structure of the high affinity ...... e C pleckstrin homology domain
@nl
P2093
P3181
P1433
P1476
Structure of the high affinity ...... e C pleckstrin homology domain
@en
P2093
J Schlessinger
K M Ferguson
P B Sigler
P304
P3181
P356
10.1016/0092-8674(95)90219-8
P407
P577
1995-12-01T00:00:00Z