A complex of Cdc4p, Skp1p, and Cdc53p/cullin catalyzes ubiquitination of the phosphorylated CDK inhibitor Sic1p.
about
The F-box protein family.The F-box protein Cdc4/Fbxw7 is a novel regulator of neural crest development in Xenopus laevisSignal-induced ubiquitination of IkappaBalpha by the F-box protein Slimb/beta-TrCPIdentification of the receptor component of the IkappaBalpha-ubiquitin ligaseHuman Cdc34 and Rad6B ubiquitin-conjugating enzymes target repressors of cyclic AMP-induced transcription for proteolysisCullin-3 targets cyclin E for ubiquitination and controls S phase in mammalian cellsThe ubiquitin-conjugating enzymes UbcH7 and UbcH8 interact with RING finger/IBR motif-containing domains of HHARI and H7-AP1Stem-loop binding protein, the protein that binds the 3' end of histone mRNA, is cell cycle regulated by both translational and posttranslational mechanismsInsights into SCF ubiquitin ligases from the structure of the Skp1-Skp2 complexATF4 degradation relies on a phosphorylation-dependent interaction with the SCF(betaTrCP) ubiquitin ligaseAPC2 Cullin protein and APC11 RING protein comprise the minimal ubiquitin ligase module of the anaphase-promoting complexThe F-box protein FBX4 targets PIN2/TRF1 for ubiquitin-mediated degradation and regulates telomere maintenanceProteasomal degradation of the multifunctional regulator YB-1 is mediated by an F-Box protein induced during programmed cell deathA growth factor-dependent nuclear kinase phosphorylates p27(Kip1) and regulates cell cycle progression.SCFbeta-TRCP controls clock-dependent transcription via casein kinase 1-dependent degradation of the mammalian period-1 (Per1) proteinInsights into Lafora disease: malin is an E3 ubiquitin ligase that ubiquitinates and promotes the degradation of laforin.Priming and extending: a UbcH5/Cdc34 E2 handoff mechanism for polyubiquitination on a SCF substrateWDRPUH, a novel WD-repeat-containing protein, is highly expressed in human hepatocellular carcinoma and involved in cell proliferationParkin-dependent degradation of the F-box protein Fbw7β promotes neuronal survival in response to oxidative stress by stabilizing Mcl-1Deubiquitinases sharpen substrate discrimination during membrane protein degradation from the ERCloning and expression analysis of a novel salicylate suppressible gene, Hs-CUL-3, a member of cullin/Cdc53 familyRegulation of Chk2 ubiquitination and signaling through autophosphorylation of serine 379WD40 protein FBW5 promotes ubiquitination of tumor suppressor TSC2 by DDB1-CUL4-ROC1 ligaseUbiquitin ligase activity of Cul3-KLHL7 protein is attenuated by autosomal dominant retinitis pigmentosa causative mutationUBE2QL1 is disrupted by a constitutional translocation associated with renal tumor predisposition and is a novel candidate renal tumor suppressor geneVHL-box and SOCS-box domains determine binding specificity for Cul2-Rbx1 and Cul5-Rbx2 modules of ubiquitin ligasesA phosphorylated cytoplasmic autoantigen, GW182, associates with a unique population of human mRNAs within novel cytoplasmic specklesPhosphorylation of nuclear MyoD is required for its rapid degradation.Disruption of centrosome structure, chromosome segregation, and cytokinesis by misexpression of human Cdc14A phosphatase.Association of human CUL-1 and ubiquitin-conjugating enzyme CDC34 with the F-box protein p45(SKP2): evidence for evolutionary conservation in the subunit composition of the CDC34-SCF pathwayAn F-box protein, FWD1, mediates ubiquitin-dependent proteolysis of beta-cateninThe products of the yeast MMS2 and two human homologs (hMMS2 and CROC-1) define a structurally and functionally conserved Ubc-like protein familySEL-10 is an inhibitor of notch signaling that targets notch for ubiquitin-mediated protein degradationThe CUL1 C-terminal sequence and ROC1 are required for efficient nuclear accumulation, NEDD8 modification, and ubiquitin ligase activity of CUL1Nedd8 modification of cul-1 activates SCF(beta(TrCP))-dependent ubiquitination of IkappaBalphaPhosphorylation of stem-loop binding protein (SLBP) on two threonines triggers degradation of SLBP, the sole cell cycle-regulated factor required for regulation of histone mRNA processing, at the end of S phaseDistinct subcellular localization patterns contribute to functional specificity of the Cln2 and Cln3 cyclins of Saccharomyces cerevisiaeE2-25K mediates US11-triggered retro-translocation of MHC class I heavy chains in a permeabilized cell systemCdc4, a protein required for the onset of S phase, serves an essential function during G(2)/M transition in Saccharomyces cerevisiaeRegulation of cyclin A-Cdk2 by SCF component Skp1 and F-box protein Skp2
P2860
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P248
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P2860
A complex of Cdc4p, Skp1p, and Cdc53p/cullin catalyzes ubiquitination of the phosphorylated CDK inhibitor Sic1p.
description
1997 nî lūn-bûn
@nan
1997 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
A complex of Cdc4p, Skp1p, and ...... horylated CDK inhibitor Sic1p.
@ast
A complex of Cdc4p, Skp1p, and ...... horylated CDK inhibitor Sic1p.
@en
A complex of Cdc4p, Skp1p, and ...... horylated CDK inhibitor Sic1p.
@nl
type
label
A complex of Cdc4p, Skp1p, and ...... horylated CDK inhibitor Sic1p.
@ast
A complex of Cdc4p, Skp1p, and ...... horylated CDK inhibitor Sic1p.
@en
A complex of Cdc4p, Skp1p, and ...... horylated CDK inhibitor Sic1p.
@nl
prefLabel
A complex of Cdc4p, Skp1p, and ...... horylated CDK inhibitor Sic1p.
@ast
A complex of Cdc4p, Skp1p, and ...... horylated CDK inhibitor Sic1p.
@en
A complex of Cdc4p, Skp1p, and ...... horylated CDK inhibitor Sic1p.
@nl
P2093
P3181
P1433
P1476
A complex of Cdc4p, Skp1p, and ...... horylated CDK inhibitor Sic1p.
@en
P2093
C C Correll
K B Kaplan
R J Deshaies
R M Feldman
P304
P3181
P356
10.1016/S0092-8674(00)80404-3
P407
P577
1997-10-17T00:00:00Z