Activity of MDM2, a ubiquitin ligase, toward p53 or itself is dependent on the RING finger domain of the ligase - Test2 - elhamkhani - TriplyDB

Activity of MDM2, a ubiquitin ligase, toward p53 or itself is dependent on the RING finger domain of the ligase

Activity of MDM2, a ubiquitin ligase, toward p53 or itself is dependent on the RING finger domain of the ligase

http://www.wikidata.org/entity/Q28139082

about

The RING-H2 finger protein APC11 and the E2 enzyme UBC4 are sufficient to ubiquitinate substrates of the anaphase-promoting complex Stabilization and activation of p53 by the coactivator protein TAFII31 TRIAD1 inhibits MDM2-mediated p53 ubiquitination and degradation Turning the RING domain protein MdmX into an active ubiquitin-protein ligase The deubiquitinating enzyme USP2a regulates the p53 pathway by targeting Mdm2 Critical role for Daxx in regulating Mdm2 A novel p53-inducible apoptogenic gene, PRG3, encodes a homologue of the apoptosis-inducing factor (AIF)Caspase-2-mediated cleavage of Mdm2 creates a p53-induced positive feedback loop Kaposi's sarcoma-associated herpesvirus viral interferon regulatory factor 4 targets MDM2 to deregulate the p53 tumor suppressor pathway Mdmx enhances p53 ubiquitination by altering the substrate preference of the Mdm2 ubiquitin ligase Efficient protection and isolation of ubiquitylated proteins using tandem ubiquitin-binding entities ATM augments nuclear stabilization of DYRK2 by inhibiting MDM2 in the apoptotic response to DNA damage MdmX is a substrate for the deubiquitinating enzyme USP2a NARF, an nemo-like kinase (NLK)-associated ring finger protein regulates the ubiquitylation and degradation of T cell factor/lymphoid enhancer factor (TCF/LEF)HECT and RING finger families of E3 ubiquitin ligases at a glance Involvement of the DNA repair protein hHR23 in p53 degradation Cancer-associated mutations in the MDM2 zinc finger domain disrupt ribosomal protein interaction and attenuate MDM2-induced p53 degradation Regulation of the MDM2-p53 pathway by ribosomal protein L11 involves a post-ubiquitination mechanism Responses of genes involved in cell cycle control to diverse DNA damaging chemicals in human lung adenocarcinoma A549 cells.Structural basis of competitive recognition of p53 and MDM2 by HAUSP/USP7: implications for the regulation of the p53-MDM2 pathway RINGs of good and evil: RING finger ubiquitin ligases at the crossroads of tumour suppression and oncogenesis Clinical utility of anti-p53 auto-antibody: systematic review and focus on colorectal cancer Structure of human MDM2 complexed with RPL11 reveals the molecular basis of p53 activation The predator becomes the prey: regulating the ubiquitin system by ubiquitylation and degradation In vivo action of the HRD ubiquitin ligase complex: mechanisms of endoplasmic reticulum quality control and sterol regulation.Transcription factor TAFII250 promotes Mdm2-dependent turnover of p53 Evidence for direct interaction between Sprouty and Cbl The BAL-binding protein BBAP and related Deltex family members exhibit ubiquitin-protein isopeptide ligase activity The RING heterodimer BRCA1-BARD1 is a ubiquitin ligase inactivated by a breast cancer-derived mutation Oligomerization of the human ARF tumor suppressor and its response to oxidative stress MdmX is a RING finger ubiquitin ligase capable of synergistically enhancing Mdm2 ubiquitination Sumoylation of Mdm2 by protein inhibitor of activated STAT (PIAS) and RanBP2 enzymes A RING finger protein Praja1 regulates Dlx5-dependent transcription through its ubiquitin ligase activity for the Dlx/Msx-interacting MAGE/Necdin family protein, Dlxin-1 The ubiquitin-proteasome pathway and proteasome inhibitors Autoubiquitylation of the V(D)J recombinase protein RAG1 Regulation of p53 by Mdm2 E3 ligase function is dispensable in embryogenesis and development, but essential in response to DNA damage Establishment of a Wheat Cell-Free Synthesized Protein Array Containing 250 Human and Mouse E3 Ubiquitin Ligases to Identify Novel Interaction between E3 Ligases and Substrate Proteins Regulation of expression of the rat orthologue of mouse double minute 2 (MDM2) by H(2)O(2)-induced oxidative stress in neonatal rat cardiac myocytes HAUSP, a deubiquitinating enzyme for p53, is polyubiquitinated, polyneddylated, and dimerized Essential role of synoviolin in embryogenesis

P2860

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P2860

Activity of MDM2, a ubiquitin ligase, toward p53 or itself is dependent on the RING finger domain of the ligase

http://www.wikidata.org/entity/Q28139082

description

2000 nî lūn-bûn

@nan

2000 թուականի Մարտին հրատարակուած գիտական յօդուած

@hyw

2000 թվականի մարտին հրատարակված գիտական հոդված

@hy

2000年の論文

@ja

2000年論文

@yue

2000年論文

@zh-hant

2000年論文

@zh-hk

2000年論文

@zh-mo

2000年論文

@zh-tw

2000年论文

@wuu

name

Activity of MDM2, a ubiquitin ...... NG finger domain of the ligase

@ast

Activity of MDM2, a ubiquitin ...... NG finger domain of the ligase

@en

Activity of MDM2, a ubiquitin ...... NG finger domain of the ligase

@nl

type

label

Activity of MDM2, a ubiquitin ...... NG finger domain of the ligase

@ast

Activity of MDM2, a ubiquitin ...... NG finger domain of the ligase

@en

Activity of MDM2, a ubiquitin ...... NG finger domain of the ligase

@nl

prefLabel

Activity of MDM2, a ubiquitin ...... NG finger domain of the ligase

@ast

Activity of MDM2, a ubiquitin ...... NG finger domain of the ligase

@en

Activity of MDM2, a ubiquitin ...... NG finger domain of the ligase

@nl

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Activity of MDM2, a ubiquitin ...... NG finger domain of the ligase

@en

P2093

H Yasuda

http://www.w3.org/2001/XMLSchema#string

R Honda

http://www.w3.org/2001/XMLSchema#string

P2860

ROC1, a homolog of APC11, represents a family of cullin partners with an associated ubiquitin ligase activity

RING fingers mediate ubiquitin-conjugating enzyme (E2)-dependent ubiquitination

Activation of the ATM kinase by ionizing radiation and phosphorylation of p53

The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53

Mdm2 promotes the rapid degradation of p53

Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53

Regulation of p53 stability by Mdm2

The E2-E3 interaction in the N-end rule pathway: the RING-H2 finger of E3 is required for the synthesis of multiubiquitin chain.

Reconstitution of G1 cyclin ubiquitination with complexes containing SCFGrr1 and Rbx1.

The tyrosine kinase negative regulator c-Cbl as a RING-type, E2-dependent ubiquitin-protein ligase

P2888

P304

1473-6

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scholarly article

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1116365

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P356

10.1038/SJ.ONC.1203464

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P407

P433

11

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P478

19

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2000-03-09T00:00:00Z

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12593068

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P6179

1029110575

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P698

10723139

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