Specification of ventral neuron types is mediated by an antagonistic interaction between Shh and Gli3
about
Mediator modulates Gli3-dependent Sonic hedgehog signalingGli proteins and the control of spinal-cord patterningA gradient of Gli activity mediates graded Sonic Hedgehog signaling in the neural tubeDorsal-ventral patterning of the spinal cord requires Gli3 transcriptional repressor activityMorphogen rules: design principles of gradient-mediated embryo patterningIdentification of multiple subsets of ventral interneurons and differential distribution along the rostrocaudal axis of the developing spinal cordTectonic, a novel regulator of the Hedgehog pathway required for both activation and inhibition.Disruption of a ciliary B9 protein complex causes Meckel syndromeShh and Gli3 regulate formation of the telencephalic-diencephalic junction and suppress an isthmus-like signaling source in the forebrainMaking a grade: Sonic Hedgehog signalling and the control of neural cell fateOtx dose-dependent integrated control of antero-posterior and dorso-ventral patterning of midbrainSonic hedgehog signaling regulates Gli2 transcriptional activity by suppressing its processing and degradationPhosphorylation of Gli2 by protein kinase A is required for Gli2 processing and degradation and the Sonic Hedgehog-regulated mouse developmentHedgehog-regulated localization of Vax2 controls eye developmentForward genetics uncovers Transmembrane protein 107 as a novel factor required for ciliogenesis and Sonic hedgehog signalingPalmitoylation is required for the production of a soluble multimeric Hedgehog protein complex and long-range signaling in vertebratesComplex interactions between genes controlling trafficking in primary ciliaTubby-like protein 3 (TULP3) regulates patterning in the mouse embryo through inhibition of Hedgehog signalingThe intraflagellar transport protein IFT80 is required for cilia formation and osteogenesisGATA6 is a crucial regulator of Shh in the limb budGas1 extends the range of Hedgehog action by facilitating its signalingCilia and Hedgehog responsiveness in the mouseA direct requirement for Hedgehog signaling for normal specification of all ventral progenitor domains in the presumptive mammalian spinal cordSpecific requirements of sonic hedgehog signaling during oligodendrocyte developmentEvoD/Vo: the origins of BMP signalling in the neuroectodermTurning heads: development of vertebrate branchiomotor neurons.Otic ablation of smoothened reveals direct and indirect requirements for Hedgehog signaling in inner ear development.An amphioxus Gli gene reveals conservation of midline patterning and the evolution of hedgehog signalling diversity in chordates.Threshold-dependent BMP-mediated repression: a model for a conserved mechanism that patterns the neuroectodermPenetrance of eye defects in mice heterozygous for mutation of Gli3 is enhanced by heterozygous mutation of Pax6.Point mutations in GLI3 lead to misregulation of its subcellular localization.In the absence of Sonic hedgehog, p53 induces apoptosis and inhibits retinal cell proliferation, cell-cycle exit and differentiation in zebrafishThe Patched dependence receptor triggers apoptosis through a DRAL-caspase-9 complexBalanced Shh signaling is required for proper formation and maintenance of dorsal telencephalic midline structuresSOX2 hypomorphism disrupts development of the prechordal floor and optic cupSonic hedgehog signaling confers ventral telencephalic progenitors with distinct cortical interneuron fates.Shh and Gli3 are dispensable for limb skeleton formation but regulate digit number and identity.Widespread contribution of Gdf7 lineage to cerebellar cell types and implications for hedgehog-driven medulloblastoma formation.mRNA-Seq and microRNA-Seq whole-transcriptome analyses of rhesus monkey embryonic stem cell neural differentiation revealed the potential regulators of rosette neural stem cells.A theoretical framework for the regulation of Shh morphogen-controlled gene expression
P2860
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P2860
Specification of ventral neuron types is mediated by an antagonistic interaction between Shh and Gli3
description
2000 nî lūn-bûn
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2000 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հոտեմբերին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
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2000年论文
@wuu
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Specification of ventral neuro ...... teraction between Shh and Gli3
@ast
Specification of ventral neuro ...... teraction between Shh and Gli3
@en
Specification of ventral neuro ...... teraction between Shh and Gli3
@nl
type
label
Specification of ventral neuro ...... teraction between Shh and Gli3
@ast
Specification of ventral neuro ...... teraction between Shh and Gli3
@en
Specification of ventral neuro ...... teraction between Shh and Gli3
@nl
prefLabel
Specification of ventral neuro ...... teraction between Shh and Gli3
@ast
Specification of ventral neuro ...... teraction between Shh and Gli3
@en
Specification of ventral neuro ...... teraction between Shh and Gli3
@nl
P2860
P356
P1433
P1476
Specification of ventral neuro ...... teraction between Shh and Gli3
@en
P2093
Y Litingtung
P2860
P2888
P304
P356
10.1038/79916
P407
P577
2000-10-01T00:00:00Z