Inhibition and restoration of prolactin signal transduction by suppressors of cytokine signaling
about
Threonine 391 phosphorylation of the human prolactin receptor mediates a novel interaction with 14-3-3 proteinsSOCS-6 binds to insulin receptor substrate 4, and mice lacking the SOCS-6 gene exhibit mild growth retardationSignal transducer and activator of transcription (STAT)-induced STAT inhibitor 1 (SSI-1)/suppressor of cytokine signaling 1 (SOCS1) inhibits insulin signal transduction pathway through modulating insulin receptor substrate 1 (IRS-1) phosphorylationJanus kinases and signal transducers and activators of transcription: their roles in cytokine signaling, development and immunoregulation.The role of suppressors of cytokine signalling in human neoplasmsRegulation of expression of the rat SOCS-3 gene in hepatocytes by growth hormone, interleukin-6 and glucocorticoids mRNA analysis and promoter characterizationSOCS1 deficiency results in accelerated mammary gland development and rescues lactation in prolactin receptor-deficient micePolycystic kidneys and chronic inflammatory lesions are the delayed consequences of loss of the suppressor of cytokine signaling-1 (SOCS-1).A cytosolic protein-tyrosine phosphatase PTP1B specifically dephosphorylates and deactivates prolactin-activated STAT5a and STAT5b.Cyclophilin B as a co-regulator of prolactin-induced gene expression and function in breast cancer cells.Prolactin receptor signal transduction.Effects of prolactin on signal transduction and gene expression: possible relevance for systemic lupus erythematosus.The central role of SOCS-3 in integrating the neuro-immunoendocrine interfaceThe role of prolactin in mammary carcinoma.Regulation of cytokine-inducible SH2-containing protein (CIS) by ubiquitination and Elongin B/C interaction.c-myc as a mediator of accelerated apoptosis and involution in mammary glands lacking Socs3.Ovarian insufficiency and early pregnancy loss induced by activation of the innate immune systemAre SOCS suppressors, regulators, and degraders?CUEDC2 (CUE domain-containing 2) and SOCS3 (suppressors of cytokine signaling 3) cooperate to negatively regulate Janus kinase 1/signal transducers and activators of transcription 3 signaling.Suppressor of cytokine signaling-3 preferentially binds to the SHP-2-binding site on the shared cytokine receptor subunit gp130The role of endotoxin, TNF-alpha, and IL-6 in inducing the state of growth hormone insensitivity.Functional inactivation of CXC chemokine receptor 4-mediated responses through SOCS3 up-regulation.Neuroendocrine hormones such as growth hormone and prolactin are integral members of the immunological cytokine network.Pregnancy-induced adaptation in the neuroendocrine control of prolactin secretion.Role of c-Myb during prolactin-induced signal transducer and activator of transcription 5a signaling in breast cancer cellsBiology and significance of the JAK/STAT signalling pathways.Suppression of cytokine signaling: the SOCS perspective.Dysregulated STAT1-SOCS1 control of JAK2 promotes mammary luminal progenitor cell survival and drives ERα(+) tumorigenesis.SOCS2 correlates with malignancy and exerts growth-promoting effects in prostate cancer.Lineage-Specific and Non-specific Cytokine-Sensing Genes Respond Differentially to the Master Regulator STAT5.SOCS proteins in development and disease.Suppressor of cytokine signalling (SOCS) proteins as guardians of inflammatory responses critical for regulating insulin sensitivity.SHP-2 regulates SOCS-1-mediated Janus kinase-2 ubiquitination/degradation downstream of the prolactin receptor.Potential roles of suppressor of cytokine signaling in wound healing.Fish Suppressors of Cytokine Signaling (SOCS): Gene Discovery, Modulation of Expression and Function.Putting the brakes on arthritis: can suppressors of cytokine signaling (SOCS) suppress rheumatoid arthritis?Prolactin can modulate CD4+ T-cell response through receptor-mediated alterations in the expression of T-bet.Soluble Egg Antigen Activates M2 Macrophages via the STAT6 and PI3K Pathways, and Schistosoma Japonicum Alternatively Activates Macrophage Polarization to Improve the Survival Rate of Septic Mice.Growth hormone and prolactin receptors in adipogenesis: STAT-5 activation, suppressors of cytokine signaling, and regulation of insulin-like growth factor I.SOCS2 can enhance interleukin-2 (IL-2) and IL-3 signaling by accelerating SOCS3 degradation.
P2860
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P2860
Inhibition and restoration of prolactin signal transduction by suppressors of cytokine signaling
description
1999 nî lūn-bûn
@nan
1999 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Inhibition and restoration of ...... pressors of cytokine signaling
@ast
Inhibition and restoration of ...... pressors of cytokine signaling
@en
Inhibition and restoration of ...... pressors of cytokine signaling
@nl
type
label
Inhibition and restoration of ...... pressors of cytokine signaling
@ast
Inhibition and restoration of ...... pressors of cytokine signaling
@en
Inhibition and restoration of ...... pressors of cytokine signaling
@nl
prefLabel
Inhibition and restoration of ...... pressors of cytokine signaling
@ast
Inhibition and restoration of ...... pressors of cytokine signaling
@en
Inhibition and restoration of ...... pressors of cytokine signaling
@nl
P2093
P2860
P356
P1476
Inhibition and restoration of ...... pressors of cytokine signaling
@en
P2093
P2860
P304
P356
10.1074/JBC.274.35.24497
P407
P577
1999-08-27T00:00:00Z