Role of the SCFSkp2 ubiquitin ligase in the degradation of p21Cip1 in S phase
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Role of Polo-like kinase in the degradation of early mitotic inhibitor 1, a regulator of the anaphase promoting complex/cyclosomeCooperation of ERK and SCFSkp2 for MKP-1 destruction provides a positive feedback regulation of proliferating signalingp97/DAP5 is a ribosome-associated factor that facilitates protein synthesis and cell proliferation by modulating the synthesis of cell cycle proteinsSelective ubiquitylation of p21 and Cdt1 by UBCH8 and UBE2G ubiquitin-conjugating enzymes via the CRL4Cdt2 ubiquitin ligase complex.Phosphorylation of Skp2 regulated by CDK2 and Cdc14B protects it from degradation by APC(Cdh1) in G1 phasePCNA-dependent regulation of p21 ubiquitylation and degradation via the CRL4Cdt2 ubiquitin ligase complex.Pharmacological inactivation of Skp2 SCF ubiquitin ligase restricts cancer stem cell traits and cancer progressionNovel control of S phase of the cell cycle by ubiquitin-conjugating enzyme H7Phosphorylation-dependent degradation of c-Myc is mediated by the F-box protein Fbw7N-Terminal ubiquitination of extracellular signal-regulated kinase 3 and p21 directs their degradation by the proteasomeSpecific small molecule inhibitors of Skp2-mediated p27 degradationThe adaptor protein of the anaphase promoting complex Cdh1 is essential in maintaining replicative lifespan and in learning and memoryThe Skp2-SCF E3 ligase regulates Akt ubiquitination, glycolysis, herceptin sensitivity, and tumorigenesisClinical relevance of SKP2 alterations in metastatic melanomaCyclin G2 is degraded through the ubiquitin-proteasome pathway and mediates the antiproliferative effect of activin receptor-like kinase 7Deregulated proteolysis by the F-box proteins SKP2 and beta-TrCP: tipping the scales of cancerPhosphorylation-dependent ubiquitination of cyclin D1 by the SCF(FBX4-alphaB crystallin) complexG2E3 is a nucleo-cytoplasmic shuttling protein with DNA damage responsive localizationNovel strategies to target the ubiquitin proteasome system in multiple myelomaMotif co-regulation and co-operativity are common mechanisms in transcriptional, post-transcriptional and post-translational regulationThe role of the ubiquitin proteasome system in cerebellar development and medulloblastomaExamination of the expanding pathways for the regulation of p21 expression and activity.The role of aberrant proteolysis in lymphomagenesisRole of conformational heterogeneity in domain swapping and adapter function of the Cks proteinsThe p53 circuit boardPP2Cgamma-mediated S-phase accumulation induced by the proteasome-dependent degradation of p21(WAF1/CIP1)The SCF ubiquitin ligase: insights into a molecular machineCDK inhibitor p21 is degraded by a proliferating cell nuclear antigen-coupled Cul4-DDB1Cdt2 pathway during S phase and after UV irradiationA novel function of CRL4(Cdt2): regulation of the subunit structure of DNA polymerase δ in response to DNA damage and during the S phasePhospho-Ser/Thr-binding domains: navigating the cell cycle and DNA damage responseA novel, non-apoptotic role for Scythe/BAT3: a functional switch between the pro- and anti-proliferative roles of p21 during the cell cycleMolecular basis for viral selective replication in cancer cells: activation of CDK2 by adenovirus-induced cyclin ECDK4 T172 phosphorylation is central in a CDK7-dependent bidirectional CDK4/CDK2 interplay mediated by p21 phosphorylation at the restriction pointAdhesion-dependent Skp2 transcription requires selenocysteine tRNA gene transcription-activating factor (STAF)The ability of TRIM3 to induce growth arrest depends on RING-dependent E3 ligase activitymiR-625-3p regulates oxaliplatin resistance by targeting MAP2K6-p38 signalling in human colorectal adenocarcinoma cellsThe E3 Ligase CHIP Mediates p21 Degradation to Maintain Radioresistance.Deregulation of F-box proteins and its consequence on cancer development, progression and metastasis.p21 in cancer: intricate networks and multiple activitiesDosage of Dyrk1a shifts cells within a p21-cyclin D1 signaling map to control the decision to enter the cell cycle
P2860
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P2860
Role of the SCFSkp2 ubiquitin ligase in the degradation of p21Cip1 in S phase
description
2003 nî lūn-bûn
@nan
2003 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Role of the SCFSkp2 ubiquitin ligase in the degradation of p21Cip1 in S phase
@ast
Role of the SCFSkp2 ubiquitin ligase in the degradation of p21Cip1 in S phase
@en
Role of the SCFSkp2 ubiquitin ligase in the degradation of p21Cip1 in S phase
@nl
type
label
Role of the SCFSkp2 ubiquitin ligase in the degradation of p21Cip1 in S phase
@ast
Role of the SCFSkp2 ubiquitin ligase in the degradation of p21Cip1 in S phase
@en
Role of the SCFSkp2 ubiquitin ligase in the degradation of p21Cip1 in S phase
@nl
prefLabel
Role of the SCFSkp2 ubiquitin ligase in the degradation of p21Cip1 in S phase
@ast
Role of the SCFSkp2 ubiquitin ligase in the degradation of p21Cip1 in S phase
@en
Role of the SCFSkp2 ubiquitin ligase in the degradation of p21Cip1 in S phase
@nl
P2093
P3181
P356
P1476
Role of the SCFSkp2 ubiquitin ligase in the degradation of p21Cip1 in S phase
@en
P2093
Danielle Sitry-Shevah
Gil Bornstein
Joanna Bloom
Keiko Nakayama
P304
P3181
P356
10.1074/JBC.M301774200
P407
P577
2003-07-11T00:00:00Z