HURP is part of a Ran-dependent complex involved in spindle formation
about
Identification of a TPX2-like microtubule-associated protein in DrosophilaKinesin-5: cross-bridging mechanism to targeted clinical therapyThe astrin-kinastrin/SKAP complex localizes to microtubule plus ends and facilitates chromosome alignmentBuilding a spindle of the correct length in human cells requires the interaction between TPX2 and Aurora AA survivin-ran complex regulates spindle formation in tumor cellsTPX2 regulates the localization and activity of Eg5 in the mammalian mitotic spindleSpindle pole regulation by a discrete Eg5-interacting domain in TPX2"HURP on" we're off to the kinetochore!Non-centrosomal TPX2-Dependent Regulation of the Aurora A Kinase: Functional Implications for Healthy and Pathological Cell DivisionThe RanGTP Pathway: From Nucleo-Cytoplasmic Transport to Spindle Assembly and BeyondThe Ran Pathway in Drosophila melanogaster MitosisSpatiotemporal Regulation of Nuclear Transport Machinery and Microtubule OrganizationRegulatory mechanisms that control mitotic kinesinsComplementary activities of TPX2 and chTOG constitute an efficient importin-regulated microtubule nucleation module.The Ran-GTP gradient spatially regulates XCTK2 in the spindle.Nucleocytoplasmic shuttling of the TACC protein Mia1p/Alp7p is required for remodeling of microtubule arrays during the cell cycleSelective Aurora Kinase Inhibitors Identified Using a Taxol-Induced Checkpoint Sensitivity ScreenAurora kinase inhibitors reveal mechanisms of HURP in nucleation of centrosomal and kinetochore microtubulesMolecular mechanism of Aurora A kinase autophosphorylation and its allosteric activation by TPX2Inhibition of apoptosis by oncogenic hepatitis B virus X protein: Implications for the treatment of hepatocellular carcinomaSMARCA4-inactivating mutations increase sensitivity to Aurora kinase A inhibitor VX-680 in non-small cell lung cancersThe Ndc80 complex: integrating the kinetochore's many movements.Localized RanGTP accumulation promotes microtubule nucleation at kinetochores in somatic mammalian cellsA centriole- and RanGTP-independent spindle assembly pathway in meiosis I of vertebrate oocytesPoleward transport of TPX2 in the mammalian mitotic spindle requires dynein, Eg5, and microtubule flux.Microtubule-dependent regulation of mitotic protein degradation.JMJD5 (Jumonji Domain-containing 5) Associates with Spindle Microtubules and Is Required for Proper Mitosis.A translational regulator, PUM2, promotes both protein stability and kinase activity of Aurora-AXenopus meiotic microtubule-associated interactome.Xenopus laevis Kif18A is a highly processive kinesin required for meiotic spindle integrityMechanism and regulation of kinesin-5, an essential motor for the mitotic spindle.CDK-dependent phosphorylation of Alp7-Alp14 (TACC-TOG) promotes its nuclear accumulation and spindle microtubule assembly.RNA stimulates Aurora B kinase activity during mitosis.Abnormal kinetochore-generated pulling forces from expressing a N-terminally modified Hec1.Cyclin G-associated kinase promotes microtubule outgrowth from chromosomes during spindle assembly.Subgroup II PAK-mediated phosphorylation regulates Ran activity during mitosisFunctional central spindle assembly requires de novo microtubule generation in the interchromosomal region during anaphase.Aurora A kinase modulates actin cytoskeleton through phosphorylation of Cofilin: Implication in the mitotic process.Hepatoma upregulated protein expression is involved in the pathogenesis of human breast carcinogenesis.HURP permits MTOC sorting for robust meiotic spindle bipolarity, similar to extra centrosome clustering in cancer cells.
P2860
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P2860
HURP is part of a Ran-dependent complex involved in spindle formation
description
2006 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2006
@ast
im April 2006 veröffentlichter wissenschaftlicher Artikel
@de
scientific article (publication date: 18 April 2006)
@en
vedecký článok (publikovaný 2006/04/18)
@sk
vědecký článek publikovaný v roce 2006
@cs
wetenschappelijk artikel (gepubliceerd op 2006/04/18)
@nl
наукова стаття, опублікована у квітні 2006
@uk
مقالة علمية (نشرت في 18-4-2006)
@ar
name
HURP is part of a Ran-dependent complex involved in spindle formation
@ast
HURP is part of a Ran-dependent complex involved in spindle formation
@en
HURP is part of a Ran-dependent complex involved in spindle formation
@en-gb
HURP is part of a Ran-dependent complex involved in spindle formation
@nl
type
label
HURP is part of a Ran-dependent complex involved in spindle formation
@ast
HURP is part of a Ran-dependent complex involved in spindle formation
@en
HURP is part of a Ran-dependent complex involved in spindle formation
@en-gb
HURP is part of a Ran-dependent complex involved in spindle formation
@nl
prefLabel
HURP is part of a Ran-dependent complex involved in spindle formation
@ast
HURP is part of a Ran-dependent complex involved in spindle formation
@en
HURP is part of a Ran-dependent complex involved in spindle formation
@en-gb
HURP is part of a Ran-dependent complex involved in spindle formation
@nl
P2093
P3181
P1433
P1476
HURP is part of a Ran-dependent complex involved in spindle formation
@en
P2093
Claudia M Casanova
Maria D Koffa
Rachel Santarella
Thomas Köcher
P304
P3181
P356
10.1016/J.CUB.2006.03.056
P407
P577
2006-04-18T00:00:00Z