A mammalian protein targeted by G1-arresting rapamycin-receptor complex
about
Inhibition of mTOR by rapamycin abolishes cognitive deficits and reduces amyloid-beta levels in a mouse model of Alzheimer's diseaseThe regulation of cyclin D1 degradation: roles in cancer development and the potential for therapeutic inventionIdentification of direct protein targets of small moleculesRule-based cell systems model of aging using feedback loop motifs mediated by stress responsesA quantitative chemical proteomics approach to profile the specific cellular targets of andrographolide, a promising anticancer agent that suppresses tumor metastasisVisualization of biochemical networks in living cellsHID-1 is a peripheral membrane protein primarily associated with the medial- and trans- Golgi apparatusThe FKBP-associated protein FAP48 is an antiproliferative molecule and a player in T cell activation that increases IL2 synthesisIdentification of dominant negative mutants of Rheb GTPase and their use to implicate the involvement of human Rheb in the activation of p70S6KA novel FK506 binding protein can mediate the immunosuppressive effects of FK506 and is associated with the cardiac ryanodine receptorLRRK2 kinase regulates synaptic morphology through distinct substrates at the presynaptic and postsynaptic compartments of the Drosophila neuromuscular junctionCloning and characterization of a wortmannin-sensitive human phosphatidylinositol 4-kinaseAmygdalin inhibits genes related to cell cycle in SNU-C4 human colon cancer cellsSignaling by target of rapamycin proteins in cell growth controlMutational analysis of ribosomal S6 kinase 2 shows differential regulation of its kinase activity from that of ribosomal S6 kinase 1Cloning of a human phosphoinositide 3-kinase with a C2 domain that displays reduced sensitivity to the inhibitor wortmanninElucidating TOR signaling and rapamycin action: lessons from Saccharomyces cerevisiae.Rapamycin potentiates transforming growth factor beta-induced growth arrest in nontransformed, oncogene-transformed, and human cancer cells.The FKBP12-rapamycin-associated protein (FRAP) is a CLIP-170 kinaseThe biosynthetic gene cluster for the polyketide immunosuppressant rapamycinActivation of phosphoinositide 3-kinase by interaction with Ras and by point mutationmTOR is essential for growth and proliferation in early mouse embryos and embryonic stem cellscDNA cloning and gene mapping of a candidate human cell cycle checkpoint proteinStructure of the large FK506-binding protein FKBP51, an Hsp90-binding protein and a component of steroid receptor complexesFunctional interaction between RAFT1/FRAP/mTOR and protein kinase cdelta in the regulation of cap-dependent initiation of translationControlling protein association and subcellular localization with a synthetic ligand that induces heterodimerization of proteinsUpdates of mTOR inhibitorsmTOR activation is required for the antidepressant effects of mGluR₂/₃ blockadeThe mTOR signalling pathway in human cancerAkt and autophagy cooperate to promote survival of drug-resistant gliomamTOR: from growth signal integration to cancer, diabetes and ageingmTOR signaling in growth control and diseaseDual requirement for a newly identified phosphorylation site in p70s6kTargeting the mammalian target of rapamycin (mTOR): a new approach to treating cancerEssential and dispensable roles of ATR in cell cycle arrest and genome maintenanceRAFT1 phosphorylation of the translational regulators p70 S6 kinase and 4E-BP1Neurabin is a synaptic protein linking p70 S6 kinase and the neuronal cytoskeletonThe role of amino acid-induced mammalian target of rapamycin complex 1(mTORC1) signaling in insulin resistanceNew Potential Pharmacological Functions of Chinese Herbal Medicines via Regulation of AutophagyHypoxia-Inducible Factors (HIFs) and Phosphorylation: Impact on Stability, Localization, and Transactivity
P2860
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P2860
A mammalian protein targeted by G1-arresting rapamycin-receptor complex
description
1994 nî lūn-bûn
@nan
1994 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
name
A mammalian protein targeted by G1-arresting rapamycin-receptor complex
@ast
A mammalian protein targeted by G1-arresting rapamycin-receptor complex
@en
A mammalian protein targeted by G1-arresting rapamycin-receptor complex
@nl
type
label
A mammalian protein targeted by G1-arresting rapamycin-receptor complex
@ast
A mammalian protein targeted by G1-arresting rapamycin-receptor complex
@en
A mammalian protein targeted by G1-arresting rapamycin-receptor complex
@nl
prefLabel
A mammalian protein targeted by G1-arresting rapamycin-receptor complex
@ast
A mammalian protein targeted by G1-arresting rapamycin-receptor complex
@en
A mammalian protein targeted by G1-arresting rapamycin-receptor complex
@nl
P2093
P3181
P356
P1433
P1476
A mammalian protein targeted by G1-arresting rapamycin-receptor complex
@en
P2093
K Ichikawa
M W Albers
S L Schreiber
P2888
P3181
P356
10.1038/369756A0
P407
P577
1994-06-30T00:00:00Z
P5875
P6179
1036157661