Unrip is a component of SMN complexes active in snRNP assembly
about
Absence of gemin5 from SMN complexes in nuclear Cajal bodiesGemin8 is a novel component of the survival motor neuron complex and functions in small nuclear ribonucleoprotein assemblyGemin8 is required for the architecture and function of the survival motor neuron complexStructure of a key intermediate of the SMN complex reveals Gemin2's crucial function in snRNP assemblyDephosphorylation of survival motor neurons (SMN) by PPM1G/PP2Cgamma governs Cajal body localization and stability of the SMN complexGemin5 delivers snRNA precursors to the SMN complex for snRNP biogenesisIn vitro and in cellulo evidences for association of the survival of motor neuron complex with the fragile X mental retardation proteinGemin5-snRNA interaction reveals an RNA binding function for WD repeat domainsSMN-independent subunits of the SMN complex. Identification of a small nuclear ribonucleoprotein assembly intermediateA role for SMN exon 7 splicing in the selective vulnerability of motor neurons in spinal muscular atrophySMN in spinal muscular atrophy and snRNP biogenesisPostsymptomatic restoration of SMN rescues the disease phenotype in a mouse model of severe spinal muscular atrophy.Requirement of enhanced Survival Motoneuron protein imposed during neuromuscular junction maturation.Proteomic assessment of a cell model of spinal muscular atrophyA systematic RNAi synthetic interaction screen reveals a link between p53 and snoRNP assembly.A cell system for phenotypic screening of modifiers of SMN2 gene expression and function.The Gemin associates of survival motor neuron are required for motor function in Drosophila.Axonal-SMN (a-SMN), a protein isoform of the survival motor neuron gene, is specifically involved in axonogenesis.Reconstitution of the human U snRNP assembly machinery reveals stepwise Sm protein organizationNUFIP and the HSP90/R2TP chaperone bind the SMN complex and facilitate assembly of U4-specific proteins.Identification and characterisation of a nuclear localisation signal in the SMN associated protein, Gemin4.Chaperoning ribonucleoprotein biogenesis in health and disease.Prolyl hydroxylation regulates protein degradation, synthesis, and splicing in human induced pluripotent stem cell-derived cardiomyocytes.SMN complex localizes to the sarcomeric Z-disc and is a proteolytic target of calpainGemin3 is an essential gene required for larval motor function and pupation in Drosophila.Identification and characterization of Drosophila Snurportin reveals a role for the import receptor Moleskin/importin-7 in snRNP biogenesisStructural basis for specific recognition of pre-snRNA by Gemin5.TGF-beta-dependent and -independent roles of STRAP in cancer.Update on gene and stem cell therapy approaches for spinal muscular atrophy.Gem depletion: amyotrophic lateral sclerosis and spinal muscular atrophy crossover.Second-generation derivatives of the eukaryotic translation initiation inhibitor pateamine A targeting eIF4A as potential anticancer agents.Identifying specific protein interaction partners using quantitative mass spectrometry and bead proteomes.Role of survival motor neuron complex components in small nuclear ribonucleoprotein assembly.Serine threonine receptor-associated protein (STRAP) plays a role in the maintenance of mesenchymal morphology.The DDX6-4E-T interaction mediates translational repression and P-body assemblyNovel interactors of the Drosophila Survival Motor Neuron (SMN) Complex suggest its full conservation.Gemin4 is an essential gene in mice, and its overexpression in human cells causes relocalization of the SMN complex to the nucleoplasm.
P2860
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P2860
Unrip is a component of SMN complexes active in snRNP assembly
description
2005 nî lūn-bûn
@nan
2005 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Unrip is a component of SMN complexes active in snRNP assembly
@ast
Unrip is a component of SMN complexes active in snRNP assembly
@en
Unrip is a component of SMN complexes active in snRNP assembly
@nl
type
label
Unrip is a component of SMN complexes active in snRNP assembly
@ast
Unrip is a component of SMN complexes active in snRNP assembly
@en
Unrip is a component of SMN complexes active in snRNP assembly
@nl
prefLabel
Unrip is a component of SMN complexes active in snRNP assembly
@ast
Unrip is a component of SMN complexes active in snRNP assembly
@en
Unrip is a component of SMN complexes active in snRNP assembly
@nl
P2860
P50
P3181
P1433
P1476
Unrip is a component of SMN complexes active in snRNP assembly
@en
P2093
Alessio Maiolica
Pieranna Chiarella
P2860
P304
P3181
P356
10.1016/J.FEBSLET.2005.03.034
P407
P577
2005-04-25T00:00:00Z