Gemin5, a novel WD repeat protein component of the SMN complex that binds Sm proteins
about
Absence of gemin5 from SMN complexes in nuclear Cajal bodiesPurification of native survival of motor neurons complexes and identification of Gemin6 as a novel componentIdentification and characterization of Gemin7, a novel component of the survival of motor neuron complexGemin8 is a novel component of the survival motor neuron complex and functions in small nuclear ribonucleoprotein assemblyGemin8 is required for the architecture and function of the survival motor neuron complexStructure of a key intermediate of the SMN complex reveals Gemin2's crucial function in snRNP assemblyNumerous microRNPs in neuronal cells containing novel microRNAsmiRNPs: a novel class of ribonucleoproteins containing numerous microRNAsSMN, the spinal muscular atrophy protein, forms a pre-import snRNP complex with snurportin1 and importin betaHigh expression level of Tra2-β1 is responsible for increased SMN2 exon 7 inclusion in the testis of SMA miceA motor function for the DEAD-box RNA helicase, Gemin3, in DrosophilaFunctional mammalian spliceosomal complex E contains SMN complex proteins in addition to U1 and U2 snRNPs.Naf1 p is a box H/ACA snoRNP assembly factorGemin5 Binds to the Survival Motor Neuron mRNA to Regulate SMN ExpressionGemin5 delivers snRNA precursors to the SMN complex for snRNP biogenesisStructural insights into Gemin5-guided selection of pre-snRNAs for snRNP assemblyIn vitro and in cellulo evidences for association of the survival of motor neuron complex with the fragile X mental retardation proteinGemin5-snRNA interaction reveals an RNA binding function for WD repeat domainsStructural basis for snRNA recognition by the double-WD40 repeat domain of Gemin5Identification of gemin5 as a novel 7-methylguanosine cap-binding proteinThe RNA-binding protein Gemin5 binds directly to the ribosome and regulates global translationSMN-independent subunits of the SMN complex. Identification of a small nuclear ribonucleoprotein assembly intermediateUnrip is a component of SMN complexes active in snRNP assemblyThe SMN complex: an assembly machine for RNPsPositive regulation of ASK1-mediated c-Jun NH(2)-terminal kinase signaling pathway by the WD-repeat protein Gemin5Regulation of SMN protein stabilityA role for SMN exon 7 splicing in the selective vulnerability of motor neurons in spinal muscular atrophySMN in spinal muscular atrophy and snRNP biogenesisSystems genetic analysis of hippocampal neuroanatomy and spatial learning in mice.Lymphotropic Herpesvirus saimiri uses the SMN complex to assemble Sm cores on its small RNAs.The survival of motor neurons protein determines the capacity for snRNP assembly: biochemical deficiency in spinal muscular atrophy.The role of nuclear bodies in gene expression and disease.Sequence-specific interaction of U1 snRNA with the SMN complexGene targeting of Gemin2 in mice reveals a correlation between defects in the biogenesis of U snRNPs and motoneuron cell death.Specific sequence features, recognized by the SMN complex, identify snRNAs and determine their fate as snRNPsThe SMN complex is associated with snRNPs throughout their cytoplasmic assembly pathwayMembrane-coating lattice scaffolds in the nuclear pore and vesicle coats: commonalities, differences, challenges.Spinal muscular atrophy: recent advances and future prospects.The Gemin associates of survival motor neuron are required for motor function in Drosophila.Molecular and cellular basis of spinal muscular atrophy.
P2860
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P248
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P2860
Gemin5, a novel WD repeat protein component of the SMN complex that binds Sm proteins
description
2002 nî lūn-bûn
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2002 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի փետրվարին հրատարակված գիտական հոդված
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2002年の論文
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2002年学术文章
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2002年学术文章
@zh-cn
2002年学术文章
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2002年学术文章
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2002年学术文章
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2002年學術文章
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name
Gemin5, a novel WD repeat protein component of the SMN complex that binds Sm proteins
@ast
Gemin5, a novel WD repeat protein component of the SMN complex that binds Sm proteins
@en
Gemin5, a novel WD repeat protein component of the SMN complex that binds Sm proteins
@en-gb
Gemin5, a novel WD repeat protein component of the SMN complex that binds Sm proteins
@nl
type
label
Gemin5, a novel WD repeat protein component of the SMN complex that binds Sm proteins
@ast
Gemin5, a novel WD repeat protein component of the SMN complex that binds Sm proteins
@en
Gemin5, a novel WD repeat protein component of the SMN complex that binds Sm proteins
@en-gb
Gemin5, a novel WD repeat protein component of the SMN complex that binds Sm proteins
@nl
prefLabel
Gemin5, a novel WD repeat protein component of the SMN complex that binds Sm proteins
@ast
Gemin5, a novel WD repeat protein component of the SMN complex that binds Sm proteins
@en
Gemin5, a novel WD repeat protein component of the SMN complex that binds Sm proteins
@en-gb
Gemin5, a novel WD repeat protein component of the SMN complex that binds Sm proteins
@nl
P2093
P3181
P356
P1476
Gemin5, a novel WD repeat protein component of the SMN complex that binds Sm proteins
@en
P2093
Amelie K Gubitz
Gideon Dreyfuss
Linda Abel
Matthias Mann
P304
P3181
P356
10.1074/JBC.M109448200
P407
P577
2002-02-15T00:00:00Z