Expression of common chromosomal fragile site genes, WWOX/FRA16D and FHIT/FRA3B is downregulated by exposure to environmental carcinogens, UV, and BPDE but not by IR.
about
Fhit interaction with ferredoxin reductase triggers generation of reactive oxygen species and apoptosis of cancer cellsFragile histidine triad protein, WW domain-containing oxidoreductase protein Wwox, and activator protein 2gamma expression levels correlate with basal phenotype in breast cancerCommon fragile sites: genomic hotspots of DNA damage and carcinogenesisFhit loss in lung preneoplasia: relation to DNA damage response checkpoint activation.Molecular alterations in the tumor suppressor gene WWOX in oral leukoplakias.Oncosuppressor proteins of fragile sites are reduced in cervical cancer.WWOX, the common fragile site FRA16D gene product, regulates ATM activation and the DNA damage response.Influence of FHIT on benzo[a]pyrene-induced tumors and alopecia in mice: chemoprevention by budesonide and N-acetylcysteine.The role of WWOX polymorphisms on COPD susceptibility and pulmonary function traits in Chinese: a case-control study and family-based analysisThe JNK inhibitor SP600129 enhances apoptosis of HCC cells induced by the tumor suppressor WWOX.Role of WW domain proteins WWOX in development, prognosis, and treatment response of glioma.WWOX gene and gene product: tumor suppression through specific protein interactions.The common fragile site FRA16D gene product WWOX: roles in tumor suppression and genomic stability.Very large common fragile site genes and their potential role in cancer development.WWOX, large common fragile site genes, and cancer.WWOX modulates the ATR-mediated DNA damage checkpoint responseThe Functional Copy Number Variation-67048 in WWOX Contributes to Increased Risk of COPD in Southern and Eastern Chinese.Reduced WWOX protein expression in human astrocytoma.Loss of lung WWOX expression causes neutrophilic inflammation.
P2860
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P2860
Expression of common chromosomal fragile site genes, WWOX/FRA16D and FHIT/FRA3B is downregulated by exposure to environmental carcinogens, UV, and BPDE but not by IR.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
Expression of common chromosom ...... s, UV, and BPDE but not by IR.
@en
type
label
Expression of common chromosom ...... s, UV, and BPDE but not by IR.
@en
prefLabel
Expression of common chromosom ...... s, UV, and BPDE but not by IR.
@en
P2093
P2860
P356
P1476
Expression of common chromosom ...... s, UV, and BPDE but not by IR.
@en
P2093
C Marcelo Aldaz
Elangovan Thavathiru
John H Ludes-Meyers
Michael C MacLeod
P2860
P304
P356
10.1002/MC.20122
P577
2005-11-01T00:00:00Z