Molecular analysis of acute promyelocytic leukemia breakpoint cluster region on chromosome 17
about
RET finger protein is a transcriptional repressor and interacts with enhancer of polycomb that has dual transcriptional functionsThe growth suppressor PML represses transcription by functionally and physically interacting with histone deacetylasesCooperative interaction between retinoic acid receptor-alpha and estrogen receptor in breast cancerIntrachromosomal rearrangements fusing L-myc and rlf in small-cell lung cancerLeukemia-associated retinoic acid receptor alpha fusion partners, PML and PLZF, heterodimerize and colocalize to nuclear bodiesRIG-E, a human homolog of the murine Ly-6 family, is induced by retinoic acid during the differentiation of acute promyelocytic leukemia cellA fusion protein formed by L-myc and a novel gene in SCLCIdentification and characterization of a leukocyte-specific component of the nuclear bodyPML, a growth suppressor disrupted in acute promyelocytic leukemiaThe promyelocytic leukemia gene product (PML) forms stable complexes with the retinoblastoma proteinStructural and functional heterogeneity of nuclear bodiesSp110 localizes to the PML-Sp100 nuclear body and may function as a nuclear hormone receptor transcriptional coactivatorStructure, localization and transcriptional properties of two classes of retinoic acid receptor alpha fusion proteins in acute promyelocytic leukemia (APL): structural similarities with a new family of oncoproteinsPLZF-RAR alpha fusion proteins generated from the variant t(11;17)(q23;q21) translocation in acute promyelocytic leukemia inhibit ligand-dependent transactivation of wild-type retinoic acid receptorsFusion between a novel Krüppel-like zinc finger gene and the retinoic acid receptor-alpha locus due to a variant t(11;17) translocation associated with acute promyelocytic leukaemiaRearrangements of the retinoic acid receptor alpha and promyelocytic leukemia zinc finger genes resulting from t(11;17)(q23;q21) in a patient with acute promyelocytic leukemiaThe translocation (6;9), associated with a specific subtype of acute myeloid leukemia, results in the fusion of two genes, dek and can, and the expression of a chimeric, leukemia-specific dek-can mRNAThe Ewing's sarcoma EWS/FLI-1 fusion gene encodes a more potent transcriptional activator and is a more powerful transforming gene than FLI-1SMRT corepressor interacts with PLZF and with the PML-retinoic acid receptor alpha (RARalpha) and PLZF-RARalpha oncoproteins associated with acute promyelocytic leukemiaThe Potential of Vitamin D-Regulated Intracellular Signaling Pathways as Targets for Myeloid Leukemia TherapyUse of whole-genome sequencing to diagnose a cryptic fusion oncogene.Vitamin A, cancer treatment and prevention: the new role of cellular retinol binding proteinsRegulation of Cellular Identity in CancerPRAM-1 is a novel adaptor protein regulated by retinoic acid (RA) and promyelocytic leukemia (PML)-RA receptor alpha in acute promyelocytic leukemia cellsPromyelocytic leukemia is a direct inhibitor of SAPK2/p38 mitogen-activated protein kinaseDNA recognition by the aberrant retinoic acid receptors implicated in human acute promyelocytic leukemiaMolecular genetic aspects of human cancers: the 1993 Frank Rose Lecture.Genomic variability and alternative splicing generate multiple PML/RAR alpha transcripts that encode aberrant PML proteins and PML/RAR alpha isoforms in acute promyelocytic leukaemia.Characterization of a fusion cDNA (RARA/myl) transcribed from the t(15;17) translocation breakpoint in acute promyelocytic leukemia.Long-distance restriction mapping of the proximal long arm of human chromosome 21 with Not I linking clones.Retinoic acid, but not arsenic trioxide, degrades the PLZF/RARalpha fusion protein, without inducing terminal differentiation or apoptosis, in a RA-therapy resistant t(11;17)(q23;q21) APL patient.Translocation breakpoint of acute promyelocytic leukemia lies within the retinoic acid receptor alpha locusExtramedullary disease in acute promyelocytic leukemia.Acute promyelocytic leukemia: from treatment to genetics and back.Arsenic trioxide downregulates specificity protein (Sp) transcription factors and inhibits bladder cancer cell and tumor growthLoss of the promyelocytic leukemia protein in gastric cancer: implications for IP-10 expression and tumor-infiltrating lymphocytes.Transcription therapy for acute promyelocytic leukaemia.All-trans retinoic acid modulates the retinoic acid receptor-alpha in promyelocytic cells.Retinoic acid receptor alpha (RAralpha) Mutations in Human Leukemia.Leukaemogenesis: more than mutant genes
P2860
Q24290200-0E9EFA85-40FF-42F1-BE83-28F4163CB20DQ24290948-F1099258-A5E0-4DE1-B2C1-7200F5BB1245Q24295934-E00394BE-2239-45D4-AC36-D05BE0CCE672Q24305387-CD4B50E3-BFA3-47A8-B927-8B122512666EQ24311314-D29A7E5A-A1E8-427A-87D6-B40C2E84CA02Q24316562-7E0B680B-080F-46B3-931F-34341FEE4C65Q24317183-E1BCAB93-9229-443A-AC48-3E970A80B2AAQ24319438-0C10B997-AB8B-4F26-BCAC-699A1FA0D45DQ24324168-9CC00683-9012-4E23-A391-574F02849F06Q24324766-10DEF515-5F49-473A-8F5E-14116BE2F5BFQ24517779-56102F7F-A6BC-4940-9B09-936D2F457AA1Q24552333-45FB06B8-4859-4EAC-AF3E-B14A33EC082BQ24555702-1D72C88C-1A0E-433F-80DD-15D588373318Q24563942-D795272A-D4DF-4B8C-BAE9-E3158127BE8FQ24564693-7829D170-1E2B-415C-90E8-8A7ED87DBB04Q24597732-3EFDC689-EB36-4A3A-A5D4-C2CB66AD7AD2Q24606378-021914E6-FF62-4BB3-B805-B95CD593D408Q24629399-BF33C0EC-7766-4C7E-8016-B186C783EDC9Q24653689-82C51615-3E50-439F-8C80-11838F48FF5BQ26799596-C7964DB3-E9D0-4FAB-B2EB-9CC9EF52E258Q27851641-CB661923-43B3-4C56-962C-E4E7CA795D54Q28081177-D60683AD-6F8D-41BB-9D5A-F9159C06FB6BQ28086849-32DFC0C5-9598-489C-B451-4296E47C69E3Q28212294-33ED4E52-EFE6-42C6-BE1E-69FE15B1A950Q28273685-2A62C268-55DB-4615-9017-8AB799E0A6BFQ28359892-F9D47FC8-3EB1-4C4A-90B6-EBF40F905C0CQ30486859-7116523C-B3CF-432D-8E38-0E8E84C83AB9Q30982911-374E9CE0-ED3A-40C8-909A-907DCEFC43BBQ31159920-B89FD6CC-84CE-4EF8-8B5C-15CECBD0A9D5Q31162099-7B1B0FD5-116E-4AAD-B539-61E1C0A9BCE7Q33177365-CAD9101A-D38E-4B41-8321-25F28397DA1AQ33334769-1B4FB305-BA67-4D84-B60F-07C7496D632CQ33604339-6B3FD8A7-B39F-447C-9A29-A30F5E5E261BQ33739256-B16B02EE-43F8-4B43-978A-13F5E25C6DEAQ33976179-3A85CFC4-D409-4DB0-9076-A78FF2D3BD5AQ34056212-314834D2-4C02-4E5E-943E-0F0D6937BCC8Q34074712-A3B3FECD-C4C8-4AFC-BDEB-C2C2A604F37AQ34217815-9D69146D-72AC-4F5D-8052-1F84A9AFDB70Q34244416-5CBB027C-B59F-4624-BB98-AA64EB6A691DQ34275371-F45BD38D-B5F5-4DB2-B43D-C368F8E6A766
P2860
Molecular analysis of acute promyelocytic leukemia breakpoint cluster region on chromosome 17
description
1990 nî lūn-bûn
@nan
1990 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1990 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1990年の論文
@ja
1990年論文
@yue
1990年論文
@zh-hant
1990年論文
@zh-hk
1990年論文
@zh-mo
1990年論文
@zh-tw
1990年论文
@wuu
name
Molecular analysis of acute pr ...... luster region on chromosome 17
@ast
Molecular analysis of acute pr ...... luster region on chromosome 17
@en
Molecular analysis of acute pr ...... luster region on chromosome 17
@nl
type
label
Molecular analysis of acute pr ...... luster region on chromosome 17
@ast
Molecular analysis of acute pr ...... luster region on chromosome 17
@en
Molecular analysis of acute pr ...... luster region on chromosome 17
@nl
prefLabel
Molecular analysis of acute pr ...... luster region on chromosome 17
@ast
Molecular analysis of acute pr ...... luster region on chromosome 17
@en
Molecular analysis of acute pr ...... luster region on chromosome 17
@nl
P2093
P3181
P356
P1433
P1476
Molecular analysis of acute pr ...... luster region on chromosome 17
@en
P2093
P304
P3181
P356
10.1126/SCIENCE.2218500
P407
P577
1990-09-28T00:00:00Z