A chromatin-wide transition to H4K20 monomethylation impairs genome integrity and programmed DNA rearrangements in the mouse - Test2 - elhamkhani - TriplyDB

A chromatin-wide transition to H4K20 monomethylation impairs genome integrity and programmed DNA rearrangements in the mouse

A chromatin-wide transition to H4K20 monomethylation impairs genome integrity and programmed DNA rearrangements in the mouse

http://www.wikidata.org/entity/Q28289637

about

RNF8- and RNF168-dependent degradation of KDM4A/JMJD2A triggers 53BP1 recruitment to DNA damage sites TDRD3 is an effector molecule for arginine-methylated histone marks PR-Set7 and H4K20me1: at the crossroads of genome integrity, cell cycle, chromosome condensation, and transcription Implication of posttranslational histone modifications in nucleotide excision repair Peaks cloaked in the mist: the landscape of mammalian replication origins Common features of chromatin in aging and cancer: cause or coincidence?Sirtuin-dependent epigenetic regulation in the maintenance of genome integrity Suv4-20h histone methyltransferases promote neuroectodermal differentiation by silencing the pluripotency-associated Oct-25 gene Impact of histone H4 lysine 20 methylation on 53BP1 responses to chromosomal double strand breaks Structural and Functional Profiling of the Human Histone Methyltransferase SMYD3 The BAH domain of ORC1 links H4K20me2 to DNA replication licensing and Meier–Gorlin syndrome A novel route to product specificity in the Suv4-20 family of histone H4K20 methyltransferases Crystal structures of the human histone H4K20 methyltransferases SUV420H1 and SUV420H2 The tumor suppressor SirT2 regulates cell cycle progression and genome stability by modulating the mitotic deposition of H4K20 methylation SET8 is degraded via PCNA-coupled CRL4(CDT2) ubiquitylation in S phase and after UV irradiation MMSET regulates histone H4K20 methylation and 53BP1 accumulation at DNA damage sites Stage-specific histone modification profiles reveal global transitions in the Xenopus embryonic epigenome Chromosome fragile sites in Arabidopsis harbor matrix attachment regions that may be associated with ancestral chromosome rearrangement events H3K56me3 is a novel, conserved heterochromatic mark that largely but not completely overlaps with H3K9me3 in both regulation and localization The histone methyltransferase MMSET regulates class switch recombination Double strand break repair functions of histone H2AX Inactivation of the CRL4-CDT2-SET8/p21 ubiquitylation and degradation axis underlies the therapeutic efficacy of pevonedistat in melanoma.Prioritizing the development of mouse models for childhood brain disorders Regulation of the DNA damage response and gene expression by the Dot1L histone methyltransferase and the 53Bp1 tumour suppressor Setd5 is essential for mammalian development and the co-transcriptional regulation of histone acetylation.Chromatin modifications: the driving force of senescence and aging?Regulation of the histone H4 monomethylase PR-Set7 by CRL4(Cdt2)-mediated PCNA-dependent degradation during DNA damage.Lung cancer: a modified epigenome.Comparative analyses of SUV420H1 isoforms and SUV420H2 reveal differences in their cellular localization and effects on myogenic differentiation.Evolutionarily conserved replication timing profiles predict long-range chromatin interactions and distinguish closely related cell types.Mammalian Ino80 mediates double-strand break repair through its role in DNA end strand resection Dynamics of Rad9 chromatin binding and checkpoint function are mediated by its dimerization and are cell cycle-regulated by CDK1 activity Suv4-20h abrogation enhances telomere elongation during reprogramming and confers a higher tumorigenic potential to iPS cells Alterations of global histone H4K20 methylation during prostate carcinogenesis.CRL4(Cdt2)-mediated destruction of the histone methyltransferase Set8 prevents premature chromatin compaction in S phase.Spatial proximity and similarity of the epigenetic state of genome domains.LINT, a novel dL(3)mbt-containing complex, represses malignant brain tumour signature genes Genomic hypomethylation in the human germline associates with selective structural mutability in the human genome.Deficiency in Bre1 impairs homologous recombination repair and cell cycle checkpoint response to radiation damage in mammalian cells Identification of a novel, recurrent MBTD1-CXorf67 fusion in low-grade endometrial stromal sarcoma.

P2860

Q24306486-13F60C5E-14CA-42B5-9929-AC67DB318C82 Q24318709-0779FAEB-B857-4446-9029-2D617DC4209C Q26823191-82C72C90-7110-452C-951D-217ECF3C6066 Q26823794-623761B3-2063-4C42-A497-AD3E87E42693 Q26829115-C3B1E667-247F-4644-BE41-37663DA12E74 Q26864051-D2CBE7A2-F05D-4B7F-BA26-8684064BFB8D Q27026871-6EE1971D-F3C4-4019-8627-EF30A946FDCC Q27325576-D1AEE649-19C2-46AA-82B4-514BFFE620C9 Q27337186-594C1832-CD47-42D8-B98E-1FD894D5DEB1 Q27670941-C7323928-3037-4BED-A09E-A6333FE7CAC9 Q27677935-7BBAF7BC-F40C-495E-84F0-47A898551951 Q27679986-0410D85A-1E5C-4643-9DF9-A431521F0F60 Q27688088-9531616A-185A-4458-83C9-E66BA00DD58C Q28286787-AA04A7CA-181F-40FA-970A-0B9B4D20B707 Q28302907-D3FF8385-810B-4520-8EAB-F1850A043E5A Q28304648-2F868820-5E5F-47FA-ACD9-F7548073A320 Q28479255-13BAC3E9-4B50-4EA6-9926-2B29BDE10767 Q28484451-A4A698BB-07B5-4031-BB89-2CCDC9F94454 Q28508019-0803C40E-B2B7-4992-83D3-E86D49853915 Q28590053-A1CCD0BA-B894-4457-AA14-BF94A62CB367 Q28661754-52B3BD9A-5246-4AA5-8CB0-46149C5A2F51 Q30276526-9C0BB276-A087-4A4F-AA64-18E139B8484E Q30366940-7BEE7A3A-1BEC-4D9F-A810-E725537567ED Q31001642-28BA036F-5C56-4E93-B085-C64875F48CD2 Q32874823-5A491276-7DBC-4B97-B301-3B5E8BDFDFA5 Q33588661-702E6060-EABD-4567-9597-90B614DB338E Q33733896-CAE4C7EC-0082-47F2-B49A-9B47DCABABAE Q33781123-94F04BEB-88D8-4964-AA33-1D52049BD5D2 Q33785780-CA818DF4-19C5-4C7D-A1AC-49FC84E740F2 Q33881351-67FACAF3-7CD6-4FA9-B0F9-DBA042875194 Q34030459-DDB6047B-6F7C-4AD7-8676-4458024CE83A Q34047330-BB04E29D-7019-4766-89FE-C100533AAB7E Q34055695-6D7E5539-280A-4110-98E4-E711D05B5C6C Q34194181-9C1D60D2-95EF-49C2-9EF0-D61E4CD2302C Q34215301-01456156-7F80-4CF6-ACE7-BE7F688E2AC0 Q34229982-5D68E291-9605-4EA8-9C99-29D63D05901D Q34263149-7CC07904-EE50-4AD9-B59E-19A0391DFAFA Q34277089-CB7AD76E-F043-4127-9595-79E41867657D Q34332401-B2FE330F-6816-4F82-9941-204AFD3DBEE0 Q34365201-A130981A-244C-45BD-BE43-D758FAC03901

P2860

A chromatin-wide transition to H4K20 monomethylation impairs genome integrity and programmed DNA rearrangements in the mouse

http://www.wikidata.org/entity/Q28289637

description

2008 nî lūn-bûn

@nan

2008 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2008 թվականի օգոստոսին հրատարակված գիտական հոդված

@hy

2008年の論文

@ja

2008年論文

@yue

2008年論文

@zh-hant

2008年論文

@zh-hk

2008年論文

@zh-mo

2008年論文

@zh-tw

2008年论文

@wuu

name

A chromatin-wide transition to ...... NA rearrangements in the mouse

@ast

A chromatin-wide transition to ...... NA rearrangements in the mouse

@en

A chromatin-wide transition to ...... NA rearrangements in the mouse

@nl

type

label

A chromatin-wide transition to ...... NA rearrangements in the mouse

@ast

A chromatin-wide transition to ...... NA rearrangements in the mouse

@en

A chromatin-wide transition to ...... NA rearrangements in the mouse

@nl

prefLabel

A chromatin-wide transition to ...... NA rearrangements in the mouse

@ast

A chromatin-wide transition to ...... NA rearrangements in the mouse

@en

A chromatin-wide transition to ...... NA rearrangements in the mouse

@nl

P1433

Q28289637-70BA0038-C487-44FE-BAAC-C5EBEB1499D9

P1476

Q28289637-2FEC4417-297E-426B-A6AC-F85C466564E5

P2093

Q28289637-07A8F6C1-F750-42B1-B5F2-2BB3CE33897F

Q28289637-0D29AAD1-BA6D-40BE-A80C-1A74D2643229

Q28289637-311B2AF8-15CB-4A9C-8CA0-176968394472

Q28289637-39643F6D-67C4-4DD4-B5FD-EC64F1CEBF7A

Q28289637-5484B9C2-0637-42D7-A88C-62BCCE3E4BBF

Q28289637-7F168C12-69A6-4F7C-A7A6-9AAF40C70998

Q28289637-96DB8258-88D8-42A1-A012-78E239C3D74F

Q28289637-B869D00A-355A-47FD-AEAF-240499A88C15

Q28289637-BFFB134F-A0C6-42FA-ACFA-4794B2F6D7C9

Q28289637-D1EA640D-CEFF-4625-B84B-B2C70B18495F

P2860

Q28289637-014E74AF-4A11-4159-88EB-76266B95A284

Q28289637-016F524D-6D3E-403B-95C6-6B9AEFD7A770

Q28289637-10C1FC1B-5BE2-4040-A53E-C271E98DD7DE

Q28289637-1183773F-19DD-4C82-B68D-DFA7AE6C3685

Q28289637-19991F94-394F-467F-B407-AA56C7C80DA2

Q28289637-1F418FD4-57D8-4C8C-86EE-5903FB39F5F6

Q28289637-201EFAA0-E49E-4A00-88A4-D39F450BA7B3

Q28289637-21439BF1-B83D-4539-A086-4A2863AC0202

Q28289637-21D30036-F147-4DB8-A942-CABA701B6849

Q28289637-2364250D-5811-44AF-B75F-9E2FF4BBE523

P304

Q28289637-0ABFC423-3CFA-4069-8770-EBBF26E6EBC2

P31

Q28289637-321A0DAE-13D3-4499-9780-7DE40B758FFF

P3181

Q28289637-BD7F047D-A4F4-450D-B095-1CA3A9E452D5

P356

Q28289637-FDA1C797-AB6D-4CDA-80E4-61667AA9316A

P407

Q28289637-076AAFA1-2F46-4458-B3B6-2CDEE72EF98B

P433

Q28289637-090FCA15-78F7-48B5-9D91-44086555C751

P478

Q28289637-12AA83AA-E7CE-4AD1-8715-5CC775AD1EDE

P50

Q28289637-116CD979-B75C-463B-9213-6FE14D1A42A8

Q28289637-75C03776-835C-401D-9D6D-AA91781E5153

Q28289637-E31E0214-1D81-41D3-BC9A-19FF25922B10

Q28289637-F0CA34A4-944D-4648-A862-526D08C61FAA

P577

Q28289637-3D5CECD5-E625-41F5-B3D2-CD4DE0F61F55

P5875

Q28289637-0EFD905C-0D22-462F-A489-991AAE84F6F2

P698

Q28289637-2772671F-1CFB-4B7E-A89B-56394B95F082

P932

Q28289637-A00EF559-0614-4CB6-BDBB-25C3CBF40E9B

P3181

P356

P1433

Genes & Development

P1476

A chromatin-wide transition to ...... NA rearrangements in the mouse

@en

P2093

André Nussenzweig

http://www.w3.org/2001/XMLSchema#string

Arkady Celeste

http://www.w3.org/2001/XMLSchema#string

Elsa Callén

http://www.w3.org/2001/XMLSchema#string

Inti A De La Rosa-Velazquez

http://www.w3.org/2001/XMLSchema#string

Mark T Bedford

http://www.w3.org/2001/XMLSchema#string

Michaela Pagani

http://www.w3.org/2001/XMLSchema#string

Monika Kauer

http://www.w3.org/2001/XMLSchema#string

Roopsha Sengupta

http://www.w3.org/2001/XMLSchema#string

Stephen Malin

http://www.w3.org/2001/XMLSchema#string

Susanne Opravil

http://www.w3.org/2001/XMLSchema#string

P2860

L3MBTL1, a histone-methylation-dependent chromatin lock

A silencing pathway to induce H3-K9 and H4-K20 trimethylation at constitutive heterochromatin

Structural basis for the methylation state-specific recognition of histone H4-K20 by 53BP1 and Crb2 in DNA repair

Mitotic-specific methylation of histone H4 Lys 20 follows increased PR-Set7 expression and its localization to mitotic chromosomes.

G9a histone methyltransferase plays a dominant role in euchromatic histone H3 lysine 9 methylation and is essential for early embryogenesis

A chromosomal memory triggered by Xist regulates histone methylation in X inactivation

Role of Dot1-dependent histone H3 methylation in G1 and S phase DNA damage checkpoint functions of Rad9.

Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer

Molecular mechanisms of mammalian DNA repair and the DNA damage checkpoints

Methylated lysine 79 of histone H3 targets 53BP1 to DNA double-strand breaks

P304

2048-61

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P3181

785795

http://www.w3.org/2001/XMLSchema#string

P356

10.1101/GAD.476008

http://www.w3.org/2001/XMLSchema#string

P407

P433

15

http://www.w3.org/2001/XMLSchema#string

P478

22

http://www.w3.org/2001/XMLSchema#string

P50

Meinrad Busslinger

Alexsandra Espejo

P577

2008-08-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

23146120

http://www.w3.org/2001/XMLSchema#string

P698

18676810

http://www.w3.org/2001/XMLSchema#string

P932

2492754

http://www.w3.org/2001/XMLSchema#string