Regulation of the histone H4 monomethylase PR-Set7 by CRL4(Cdt2)-mediated PCNA-dependent degradation during DNA damage. - Test2 - elhamkhani - TriplyDB

Regulation of the histone H4 monomethylase PR-Set7 by CRL4(Cdt2)-mediated PCNA-dependent degradation during DNA damage.

Regulation of the histone H4 monomethylase PR-Set7 by CRL4(Cdt2)-mediated PCNA-dependent degradation during DNA damage.

http://www.wikidata.org/entity/Q33733896

about

Selective ubiquitylation of p21 and Cdt1 by UBCH8 and UBE2G ubiquitin-conjugating enzymes via the CRL4Cdt2 ubiquitin ligase complex.Dynamics of DNA damage response proteins at DNA breaks: a focus on protein modifications Writers, Readers, and Erasers of Histone Ubiquitylation in DNA Double-Strand Break Repair The role and mechanism of CRL4 E3 ubiquitin ligase in cancer and its potential therapy implications PR-Set7 and H4K20me1: at the crossroads of genome integrity, cell cycle, chromosome condensation, and transcription Sequential replication-coupled destruction at G1/S ensures genome stability.Impact of histone H4 lysine 20 methylation on 53BP1 responses to chromosomal double strand breaks Acetylation limits 53BP1 association with damaged chromatin to promote homologous recombination CRL4-like Clr4 complex in Schizosaccharomyces pombe depends on an exposed surface of Dos1 for heterochromatin silencing Lysine methylation-dependent binding of 53BP1 to the pRb tumor suppressor Multivalent Interactions by the Set8 Histone Methyltransferase With Its Nucleosome Substrate The emerging role of lysine methyltransferase SETD8 in human diseases Distinct and overlapping functions of the cullin E3 ligase scaffolding proteins CUL4A and CUL4B The tumor suppressor SirT2 regulates cell cycle progression and genome stability by modulating the mitotic deposition of H4K20 methylation Genetic abolishment of hepatocyte proliferation activates hepatic stem cells X-linked mental retardation gene CUL4B targets ubiquitylation of H3K4 methyltransferase component WDR5 and regulates neuronal gene expression The histone methyltransferase MMSET regulates class switch recombination Inactivation of the CRL4-CDT2-SET8/p21 ubiquitylation and degradation axis underlies the therapeutic efficacy of pevonedistat in melanoma.CRL4Cdt2 E3 ubiquitin ligase and proliferating cell nuclear antigen (PCNA) cooperate to degrade thymine DNA glycosylase in S phase Degradation of p12 subunit by CRL4Cdt2 E3 ligase inhibits fork progression after DNA damage.Regulation of TGF-β signaling, exit from the cell cycle, and cellular migration through cullin cross-regulation: SCF-FBXO11 turns off CRL4-Cdt2.CRL1-FBXO11 promotes Cdt2 ubiquitylation and degradation and regulates Pr-Set7/Set8-mediated cellular migration.The SKP1-Cul1-F-box and leucine-rich repeat protein 4 (SCF-FbxL4) ubiquitin ligase regulates lysine demethylase 4A (KDM4A)/Jumonji domain-containing 2A (JMJD2A) protein.CRL4Cdt2: master coordinator of cell cycle progression and genome stability A SILAC-based screen for Methyl-CpG binding proteins identifies RBP-J as a DNA methylation and sequence-specific binding protein Histone-binding domains: strategies for discovery and characterization.The UBC9 E2 SUMO conjugating enzyme binds the PR-Set7 histone methyltransferase to facilitate target gene repression.Fluorescence-based methods for screening writers and readers of histone methyl marks.EGFR modulates DNA synthesis and repair through Tyr phosphorylation of histone H4.The stress phenotype makes cancer cells addicted to CDT2, a substrate receptor of the CRL4 ubiquitin ligase.A role of tomato UV-damaged DNA binding protein 1 (DDB1) in organ size control via an epigenetic manner The histone H4 lysine 20 monomethyl mark, set by PR-Set7 and stabilized by L(3)mbt, is necessary for proper interphase chromatin organization.Checkpoint kinase ATR phosphorylates Cdt2, a substrate receptor of CRL4 ubiquitin ligase, and promotes the degradation of Cdt1 following UV irradiation.DNA double-strand break repair: a tale of pathway choices.Proteome identification of proteins interacting with histone methyltransferase SET8.Histone H4 lysine 20 methylation: key player in epigenetic regulation of genomic integrity.Non-canonical CRL4A/4B(CDT2) interacts with RAD18 to modulate post replication repair and cell survival.The 53BP1 homolog in C. elegans influences DNA repair and promotes apoptosis in response to ionizing radiation Defining the replication program through the chromatin landscape Mechanisms of x chromosome dosage compensation.

P2860

Q24305063-BC81E42D-0142-4E02-90EC-44CE251D98C3 Q24608343-99A3456E-BBFA-44EB-8C42-E6469F602290 Q26742134-3CD33123-6A34-4F54-BBF6-EE88084F3A0E Q26783814-A1EE39DB-AD45-4CF6-AF16-6EB656B50BB7 Q26823191-1BB41F66-3331-4F17-9E15-AA8664C160B9 Q27322859-63A418F3-7C9A-44A0-A97A-500F3A229E2E Q27337186-9D105908-C4DC-4149-9521-A7E9B6460ADE Q27676128-013810F5-B75C-4098-8F61-03DF058B9A95 Q27681419-E147C22A-CC7A-4131-B080-AA60C2F2F93A Q27684769-CBA45302-B927-47F6-91D8-401FD7CD9E54 Q27704231-C1C70D37-B5F8-49E8-90E3-ED64249BBFCF Q28079964-4C0AB533-DB2A-491C-83A4-FD3D51070F23 Q28086765-A4A2C93B-BBE1-4634-BC60-2F3A5074179E Q28286787-A7E8710D-FE6B-46AC-AF6A-5970A59F79CC Q28481211-83645D46-0093-46BB-97C8-78ABD485C0DE Q28578733-2C53D9AD-24ED-410F-82F7-81497DDA3FCC Q28590053-2CA814DA-7090-4E37-9F6B-AE9F3FFBC441 Q30276526-BBDB5586-6B85-4987-904C-8B327817B51B Q30371382-F92A7385-D80D-4F07-BB5E-830936184A55 Q30410142-F417B8ED-B203-4729-BF17-77FBDED42150 Q30411902-FC7CA98A-7E08-403A-B283-EE460BCF0EF1 Q30414178-182EEC9E-D8ED-40B4-B156-340E685F45D1 Q30430764-D56CCCC9-CA23-47E9-B2EF-BCBBE911135C Q30433428-A8D63926-E74B-42E2-BE72-76E0C761565B Q31032788-4E0F950F-CCEA-400D-BBD5-F28C83186246 Q33905467-31B6D5D9-5D4C-48FA-9891-4692EA078929 Q33987877-D42AC2F5-2883-4F69-99D7-6C01BF1A03F9 Q34040118-E5E4AB45-3759-4AA0-B8F7-62917605A344 Q34109344-571C0BAE-9DD3-415B-8E5A-09B5B34A0941 Q34227548-6968BCDF-E1D2-4A89-93D6-90CB71DE6CFD Q34395529-31E7C01E-7C0C-4915-9E6B-32DCCB98BC5E Q34425328-031665CC-FF63-44B4-B6CF-238193D9C8BA Q34431295-18582AC1-CDA6-4527-BDEF-3629313EDE25 Q34528005-5889044F-2621-4FD7-AEB8-9B6358CFE65B Q34590893-93521892-F4B3-4685-8804-9F1181039304 Q34647591-AB75E1DF-16FF-44BC-B7FF-1FF72FC59F82 Q34652883-471FCCCB-A6F8-490C-9C1B-4C3C9E9CE13A Q34718519-7BE28711-50D8-46E4-B060-1DBC877151D9 Q34780596-2A454A31-0677-4E32-A448-B1793DE77DB4 Q35002469-5946F879-9FB8-43C7-90EA-F028D0FBCFF1

P2860

Regulation of the histone H4 monomethylase PR-Set7 by CRL4(Cdt2)-mediated PCNA-dependent degradation during DNA damage.

http://www.wikidata.org/entity/Q33733896

description

2010 nî lūn-bûn

@nan

2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հոտեմբերին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

Regulation of the histone H4 m ...... degradation during DNA damage.

@ast

Regulation of the histone H4 m ...... degradation during DNA damage.

@en

type

label

Regulation of the histone H4 m ...... degradation during DNA damage.

@ast

Regulation of the histone H4 m ...... degradation during DNA damage.

@en

prefLabel

Regulation of the histone H4 m ...... degradation during DNA damage.

@ast

Regulation of the histone H4 m ...... degradation during DNA damage.

@en

P1433

Q33733896-1BF55E17-1773-4287-B491-48E707771B09

P1476

Q33733896-F496CADE-AAB3-4149-BBC2-9C6A4C9DF264

P2093

Q33733896-1DD7BE9A-0434-4569-8795-0857688434F1

Q33733896-31A30E50-6B6A-44A1-B101-D931E740B68A

Q33733896-6069C74C-4228-4CB8-BCBA-04461A7398F4

Q33733896-9CA4A397-16E9-4E74-AAE9-EEBE06B17F5F

Q33733896-C3009765-D570-45BA-BCBE-691BEE7B8C27

P2860

Q33733896-075F72FE-F88E-4945-A820-87978125214A

Q33733896-07FC5EC9-3AF6-4404-9F38-F2204956C881

Q33733896-0AB151AF-06CA-43B1-A868-4C3640E9C006

Q33733896-1CDE1D09-45B7-4BED-BF91-6DC65D00AA20

Q33733896-2385C152-0FF4-4662-B8B3-668605F59209

Q33733896-336C01A5-1B20-4699-9686-84BFF2F44E42

Q33733896-38DE824A-B23B-48FF-90F6-7CDBD6F253B8

Q33733896-399F32E0-4DF9-40EC-A6F8-BF560866F96D

Q33733896-4328075E-56A1-4D85-B67C-8BA2F4E5398B

Q33733896-460B8A9C-2035-4E34-B095-03CFE2FCD493

P304

Q33733896-9FB1B66F-E583-44BD-8AD5-3B78022D0BF2

P31

Q33733896-323A693B-1165-40EF-908E-3AC5585864FB

P356

Q33733896-5A36B3CA-7AB7-4C72-A095-87ECA12A1407

P433

Q33733896-0683DD0D-FBC4-4A61-BE99-10478615035F

P478

Q33733896-735394AE-6F85-4D57-B2F6-A014D866086D

P50

Q33733896-519A85DF-7DE2-4D7E-A929-AE4CEE6F4E52

Q33733896-F6A395DD-4959-4254-ACB7-0D64A6826D4B

P577

Q33733896-D14F0A38-B10F-4B92-9ED4-28B08EBE268C

P5875

Q33733896-AD4447DD-C12C-422C-A422-F9B4D78A6191

P698

Q33733896-2CF914F8-C380-4B7F-8329-073C30A1B09A

P921

Q33733896-A80E133D-20BA-4234-8BF1-BCCE3B92F0C7

P932

Q33733896-2F0FC94D-1E64-4231-B26B-7AA06EF540F4

P356

J.MOLCEL.2010.10.011

P1433

P1476

Regulation of the histone H4 m ...... degradation during DNA damage.

@en

P2093

David B Beck

http://www.w3.org/2001/XMLSchema#string

David L Spector

http://www.w3.org/2001/XMLSchema#string

Hisanobu Oda

http://www.w3.org/2001/XMLSchema#string

Jerard Hurwitz

http://www.w3.org/2001/XMLSchema#string

Michael R Hübner

http://www.w3.org/2001/XMLSchema#string

P2860

Selective anchoring of TFIID to nucleosomes by trimethylation of histone H3 lysine 4

Two E3 ubiquitin ligases, SCF-Skp2 and DDB1-Cul4, target human Cdt1 for proteolysis.

PCNA-dependent regulation of p21 ubiquitylation and degradation via the CRL4Cdt2 ubiquitin ligase complex.

Modulation of p53 function by SET8-mediated methylation at lysine 382

Nuclear dynamics of PCNA in DNA replication and repair.

Intrinsic negative cell cycle regulation provided by PIP box- and Cul4Cdt2-mediated destruction of E2f1 during S phase

Structural basis for the methylation state-specific recognition of histone H4-K20 by 53BP1 and Crb2 in DNA repair

Mitotic-specific methylation of histone H4 Lys 20 follows increased PR-Set7 expression and its localization to mitotic chromosomes.

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

The role of chromatin during transcription

P304

364-376

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1016/J.MOLCEL.2010.10.011

http://www.w3.org/2001/XMLSchema#string

P433

3

http://www.w3.org/2001/XMLSchema#string

P478

40

http://www.w3.org/2001/XMLSchema#string

P50

Michiel Vermeulen

P577

2010-10-28T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

47634091

http://www.w3.org/2001/XMLSchema#string

P698

21035370

http://www.w3.org/2001/XMLSchema#string

P921

P932

2999913

http://www.w3.org/2001/XMLSchema#string