Mixed lineage kinase-dependent JNK activation is governed by interactions of scaffold protein JIP with MAPK module components.
about
A new identity for MLK3 as an NIMA-related, cell cycle-regulated kinase that is localized near centrosomes and influences microtubule organization.Fibroblast growth factor homologous factors and the islet brain-2 scaffold protein regulate activation of a stress-activated protein kinaseA unique set of SH3-SH3 interactions controls IB1 homodimerization.Src family kinases directly regulate JIP1 module dynamics and activationPhosphorylation of Pax2 by the c-Jun N-terminal kinase and enhanced Pax2-dependent transcription activationRecruitment of JNK to JIP1 and JNK-dependent JIP1 phosphorylation regulates JNK module dynamics and activationMixed lineage kinase 2 interacts with clathrin and influences clathrin-coated vesicle traffickingPositive regulation of ASK1-mediated c-Jun NH(2)-terminal kinase signaling pathway by the WD-repeat protein Gemin5RPM-1 uses both ubiquitin ligase and phosphatase-based mechanisms to regulate DLK-1 during neuronal developmentZPK/DLK and MKK4 form the critical gateway to axotomy-induced motoneuron death in neonatesMLK3 regulates fMLP-stimulated neutrophil motility.Cdc42 induces activation loop phosphorylation and membrane targeting of mixed lineage kinase 3.Autoinhibition of mixed lineage kinase 3 through its Src homology 3 domain.Axon regeneration requires a conserved MAP kinase pathway.Reassembly of JIP1 scaffold complex in JNK MAP kinase pathway using heterologous protein interactionsProtocadherin FAT1 binds Ena/VASP proteins and is necessary for actin dynamics and cell polarization.Disassembly of the JIP1/JNK molecular scaffold by caspase-3-mediated cleavage of JIP1 during apoptosisMixed-lineage kinase control of JNK and p38 MAPK pathways.A conditioning lesion protects axons from degeneration via the Wallenda/DLK MAP kinase signaling cascadePAK and other Rho-associated kinases--effectors with surprisingly diverse mechanisms of regulationDissociation of Akt1 from its negative regulator JIP1 is mediated through the ASK1-MEK-JNK signal transduction pathway during metabolic oxidative stress: a negative feedback loop.Lysine 63-linked ubiquitination modulates mixed lineage kinase-3 interaction with JIP1 scaffold protein in cytokine-induced pancreatic β cell deathMixed lineage kinases (MLKs): a role in dendritic cells, inflammation and immunity?The interferon signaling network and transcription factor C/EBP-betaIndependent pathways downstream of the Wnd/DLK MAPKKK regulate synaptic structure, axonal transport, and injury signalingInhibition of human insulin gene transcription and MafA transcriptional activity by the dual leucine zipper kinaseDual leucine zipper kinase as a therapeutic target for neurodegenerative conditions.Direct interaction of the molecular scaffolds POSH and JIP is required for apoptotic activation of JNKs.TNFα-induced DLK activation contributes to apoptosis in the beta-cell line HIT.Dual leucine zipper kinase (MAP3K12) modulators: a patent review (2010-2015).Induced, selective proteolysis of MLK3 negatively regulates MLK3/JNK signalling.Dynamic positive feedback phosphorylation of mixed lineage kinase 3 by JNK reversibly regulates its distribution to Triton-soluble domains.Identification and analysis of a novel dimerization domain shared by various members of c-Jun N-terminal kinase (JNK) scaffold proteins.Gravin is a transitory effector of polo-like kinase 1 during cell division.Identification of the critical features of a small peptide inhibitor of JNK activity.Increased vulnerability to kainic acid-induced epileptic seizures in mice underexpressing the scaffold protein Islet-Brain 1/JIP-1.Docking interactions in the c-Jun N-terminal kinase pathway.Down-regulation of the mixed-lineage dual leucine zipper-bearing kinase by heat shock protein 70 and its co-chaperone CHIP.Nerve Growth Factor-induced p75-mediated Death of Cultured Hippocampal Neurons Is Age-dependent and Transduced through Ceramide Generated by Neutral Sphingomyelinase
P2860
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P2860
Mixed lineage kinase-dependent JNK activation is governed by interactions of scaffold protein JIP with MAPK module components.
description
2001 nî lūn-bûn
@nan
2001 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Mixed lineage kinase-dependent ...... IP with MAPK module components
@nl
Mixed lineage kinase-dependent ...... P with MAPK module components.
@ast
Mixed lineage kinase-dependent ...... P with MAPK module components.
@en
type
label
Mixed lineage kinase-dependent ...... IP with MAPK module components
@nl
Mixed lineage kinase-dependent ...... P with MAPK module components.
@ast
Mixed lineage kinase-dependent ...... P with MAPK module components.
@en
prefLabel
Mixed lineage kinase-dependent ...... IP with MAPK module components
@nl
Mixed lineage kinase-dependent ...... P with MAPK module components.
@ast
Mixed lineage kinase-dependent ...... P with MAPK module components.
@en
P2093
P2860
P356
P1433
P1476
Mixed lineage kinase-dependent ...... P with MAPK module components.
@en
P2093
P2860
P304
P356
10.1093/EMBOJ/20.13.3447
P407
P577
2001-07-01T00:00:00Z