A dual functional signal mediator showing RhoGAP and phospholipase C-delta stimulating activities
about
DLC-1: a Rho GTPase-activating protein and tumour suppressorDLC-1 suppresses non-small cell lung cancer growth and invasion by RhoGAP-dependent and independent mechanismsThe phosphotyrosine-independent interaction of DLC-1 and the SH2 domain of cten regulates focal adhesion localization and growth suppression activity of DLC-1The RhoGAP protein DLC-1 functions as a metastasis suppressor in breast cancer cellsDeleted in liver cancer-1 (DLC-1): a tumor suppressor not just for liverThe GTPase-activating protein n-chimaerin cooperates with Rac1 and Cdc42Hs to induce the formation of lamellipodia and filopodiaIdentification and characterization of Ral-binding protein 1, a potential downstream target of Ral GTPasesDeleted in liver cancer-1 (DLC1): an emerging metastasis suppressor geneCalcium signaling in live cells on elastic gels under mechanical vibration at subcellular levelsAn essential function of a phosphoinositide-specific phospholipase C is relieved by inhibition of a cyclin-dependent protein kinase in the yeast Saccharomyces cerevisiaeInteractions of G(h)/transglutaminase with phospholipase Cdelta1 and with GTPA novel isoform of the 8p22 tumor suppressor gene DLC1 suppresses tumor growth and is frequently silenced in multiple common tumorsMutations in the focal adhesion targeting region of deleted in liver cancer-1 attenuate their expression and functionDeleted in liver cancer protein family in human malignancies (Review)The Deleted in Liver Cancer 1 (Dlc1) tumor suppressor is haploinsufficient for mammary gland development and epithelial cell polarityDLC1 activation requires lipid interaction through a polybasic region preceding the RhoGAP domainTensin1 positively regulates RhoA activity through its interaction with DLC1Identification and characterization of Dlc1 isoforms in the mouse and study of the biological function of a single gene trapped isoformRole of DLC1 tumor suppressor gene and MYC oncogene in pathogenesis of human hepatocellular carcinoma: potential prospects for combined targeted therapeutics (review)Dlc1 interaction with non-muscle myosin heavy chain II-A (Myh9) and Rac1 activationPhospholipase C-delta1 and -delta3 are essential in the trophoblast for placental developmentRho-associated kinase, a novel serine/threonine kinase, as a putative target for small GTP binding protein RhoThe Concise Guide to PHARMACOLOGY 2013/14: enzymes.Cytotoxic necrotizing factor type 2 produced by pathogenic Escherichia coli deamidates a gln residue in the conserved G-3 domain of the rho family and preferentially inhibits the GTPase activity of RhoA and rac1The small G protein Rac1 activates phospholipase Cdelta1 through phospholipase Cbeta2.Enhanced p122RhoGAP/DLC-1 Expression Can Be a Cause of Coronary Spasm.Minireview: Mouse Models of Rho GTPase Function in Mammary Gland Development, Tumorigenesis, and MetastasisStimulation of phospholipase Cbeta by membrane interactions, interdomain movement, and G protein binding--how many ways can you activate an enzyme?Phospholipase C-delta1 modulates sustained contraction of rat mesenteric small arteries in response to noradrenaline, but not endothelin-1Mutation of an EF-hand Ca(2+)-binding motif in phospholipase C of Dictyostelium discoideum: inhibition of activity but no effect on Ca(2+)-dependence.Phospholipase Cdelta1 is required for skin stem cell lineage commitment.Leukotriene D4-induced mobilization of intracellular Ca2+ in epithelial cells is critically dependent on activation of the small GTP-binding protein Rho.A new inositol 1,4,5-trisphosphate binding protein similar to phospholipase C-delta 1.Regulation of inositol lipid-specific phospholipase cdelta by changes in Ca2+ ion concentrations.Arabidopsis RopGAPs are a novel family of rho GTPase-activating proteins that require the Cdc42/Rac-interactive binding motif for rop-specific GTPase stimulation.Pollen tube tip growth depends on plasma membrane polarization mediated by tobacco PLC3 activity and endocytic membrane recycling.
P2860
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P2860
A dual functional signal mediator showing RhoGAP and phospholipase C-delta stimulating activities
description
1995 nî lūn-bûn
@nan
1995 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
A dual functional signal media ...... C-delta stimulating activities
@ast
A dual functional signal media ...... C-delta stimulating activities
@en
A dual functional signal media ...... C-delta stimulating activities
@nl
type
label
A dual functional signal media ...... C-delta stimulating activities
@ast
A dual functional signal media ...... C-delta stimulating activities
@en
A dual functional signal media ...... C-delta stimulating activities
@nl
prefLabel
A dual functional signal media ...... C-delta stimulating activities
@ast
A dual functional signal media ...... C-delta stimulating activities
@en
A dual functional signal media ...... C-delta stimulating activities
@nl
P2860
P1433
P1476
A dual functional signal media ...... C-delta stimulating activities
@en
P2860
P304
P356
10.1002/J.1460-2075.1995.TB07002.X
P407
P577
1995-01-01T00:00:00Z