Detectable clonal mosaicism from birth to old age and its relationship to cancer
about
Single cell genomics: advances and future perspectivesDetectable clonal mosaicism and its relationship to aging and cancerCharacterization of large structural genetic mosaicism in human autosomeSomatic mosaicism in the human genomeAcute myeloid leukaemia: a paradigm for the clonal evolution of cancer?The FHIT gene product: tumor suppressor and genome "caretaker"Female chromosome X mosaicism is age-related and preferentially affects the inactivated X chromosomeNew insights into the generation and role of de novo mutations in health and diseaseInflamm-Aging of Hematopoiesis, Hematopoietic Stem Cells, and the Bone Marrow MicroenvironmentClonal hematopoiesis in acquired aplastic anemiaThe hallmarks of agingDetection of chromosomal alterations in the circulation of cancer patients with whole-genome sequencingVariations in brain DNAGenome-wide consequences of deleting any single geneChallenging the axiom: does the occurrence of oncogenic mutations truly limit cancer development with age?Aging-Induced Stem Cell Mutations as Drivers for Disease and CancerSensitive and specific detection of mosaic chromosomal abnormalities using the Parent-of-Origin-based Detection (POD) methodToward an evolutionary model of cancer: Considering the mechanisms that govern the fate of somatic mutationsMolecular and cytogenetic characterization of expanded B-cell clones from multiclonal versus monoclonal B-cell chronic lymphoproliferative disordersSomatic mutations found in the healthy blood compartment of a 115-yr-old woman demonstrate oligoclonal hematopoiesisClinical Correlates of Autosomal Chromosomal Abnormalities in an Electronic Medical Record-Linked Genome-Wide Association Study: A Case Series.Republished: Non-heritable genetics of human disease: spotlight on post-zygotic genetic variation acquired during lifetimeClonal hematopoiesis and blood-cancer risk inferred from blood DNA sequenceStochastic modeling reveals an evolutionary mechanism underlying elevated rates of childhood leukemiaLeukemia-associated somatic mutations drive distinct patterns of age-related clonal hemopoiesisDetection of clonal blood cells with specific chromosomal abnormalities in the general populationAge-related clonal hematopoiesis associated with adverse outcomesChanging genetic paradigms: creating next-generation genetic databases as tools to understand the emerging complexities of genotype/phenotype relationshipsElimination of unfit cells maintains tissue health and prolongs lifespanMyelodysplastic Syndromes Diagnosis: What Is the Role of Molecular Testing?Age-related mutations associated with clonal hematopoietic expansion and malignanciesUltra-fast local-haplotype variant calling using paired-end DNA-sequencing data reveals somatic mosaicism in tumor and normal blood samplesSystematic biases in DNA copy number originate from isolation proceduresMosaic PPM1D mutations are associated with predisposition to breast and ovarian cancerAssessment of megabase-scale somatic copy number variation using single-cell sequencingA genome-wide approach for detecting novel insertion-deletion variants of mid-range sizeRuns of Homozygosity: Association with Coronary Artery Disease and Gene Expression in Monocytes and MacrophagesClinical and biological characterization of patients with low (0.1-2%) JAK2V617F allele burden at diagnosisSimilarities and differences between exome sequences found in a variety of tissues from the same individualThe role of epigenetic mechanisms and processes in autoimmune disorders
P2860
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P2860
Detectable clonal mosaicism from birth to old age and its relationship to cancer
description
2012 nî lūn-bûn
@nan
2012 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Detectable clonal mosaicism from birth to old age and its relationship to cancer
@ast
Detectable clonal mosaicism from birth to old age and its relationship to cancer
@en
Detectable clonal mosaicism from birth to old age and its relationship to cancer
@nl
type
label
Detectable clonal mosaicism from birth to old age and its relationship to cancer
@ast
Detectable clonal mosaicism from birth to old age and its relationship to cancer
@en
Detectable clonal mosaicism from birth to old age and its relationship to cancer
@nl
prefLabel
Detectable clonal mosaicism from birth to old age and its relationship to cancer
@ast
Detectable clonal mosaicism from birth to old age and its relationship to cancer
@en
Detectable clonal mosaicism from birth to old age and its relationship to cancer
@nl
P2093
P2860
P50
P3181
P356
P1433
P1476
Detectable clonal mosaicism from birth to old age and its relationship to cancer
@en
P2093
Alan F Scott
Anastasia Wise
Andrew Crenshaw
Caitlin P McHugh
Cathy C Laurie
Cecelia A Laurie
Chris Amos
Cynthia Regnier
Daniel B Mirel
David M Levine
P2860
P2888
P304
P3181
P356
10.1038/NG.2271
P407
P50
P577
2012-05-06T00:00:00Z