Detectable clonal mosaicism from birth to old age and its relationship to cancer - Test2 - elhamkhani - TriplyDB

Detectable clonal mosaicism from birth to old age and its relationship to cancer

Detectable clonal mosaicism from birth to old age and its relationship to cancer

http://www.wikidata.org/entity/Q28385149

about

Single cell genomics: advances and future perspectives Detectable clonal mosaicism and its relationship to aging and cancer Characterization of large structural genetic mosaicism in human autosome Somatic mosaicism in the human genome Acute myeloid leukaemia: a paradigm for the clonal evolution of cancer?The FHIT gene product: tumor suppressor and genome "caretaker"Female chromosome X mosaicism is age-related and preferentially affects the inactivated X chromosome New insights into the generation and role of de novo mutations in health and disease Inflamm-Aging of Hematopoiesis, Hematopoietic Stem Cells, and the Bone Marrow Microenvironment Clonal hematopoiesis in acquired aplastic anemia The hallmarks of aging Detection of chromosomal alterations in the circulation of cancer patients with whole-genome sequencing Variations in brain DNA Genome-wide consequences of deleting any single gene Challenging the axiom: does the occurrence of oncogenic mutations truly limit cancer development with age?Aging-Induced Stem Cell Mutations as Drivers for Disease and Cancer Sensitive and specific detection of mosaic chromosomal abnormalities using the Parent-of-Origin-based Detection (POD) method Toward an evolutionary model of cancer: Considering the mechanisms that govern the fate of somatic mutations Molecular and cytogenetic characterization of expanded B-cell clones from multiclonal versus monoclonal B-cell chronic lymphoproliferative disorders Somatic mutations found in the healthy blood compartment of a 115-yr-old woman demonstrate oligoclonal hematopoiesis Clinical Correlates of Autosomal Chromosomal Abnormalities in an Electronic Medical Record-Linked Genome-Wide Association Study: A Case Series.Republished: Non-heritable genetics of human disease: spotlight on post-zygotic genetic variation acquired during lifetime Clonal hematopoiesis and blood-cancer risk inferred from blood DNA sequence Stochastic modeling reveals an evolutionary mechanism underlying elevated rates of childhood leukemia Leukemia-associated somatic mutations drive distinct patterns of age-related clonal hemopoiesis Detection of clonal blood cells with specific chromosomal abnormalities in the general population Age-related clonal hematopoiesis associated with adverse outcomes Changing genetic paradigms: creating next-generation genetic databases as tools to understand the emerging complexities of genotype/phenotype relationships Elimination of unfit cells maintains tissue health and prolongs lifespan Myelodysplastic Syndromes Diagnosis: What Is the Role of Molecular Testing?Age-related mutations associated with clonal hematopoietic expansion and malignancies Ultra-fast local-haplotype variant calling using paired-end DNA-sequencing data reveals somatic mosaicism in tumor and normal blood samples Systematic biases in DNA copy number originate from isolation procedures Mosaic PPM1D mutations are associated with predisposition to breast and ovarian cancer Assessment of megabase-scale somatic copy number variation using single-cell sequencing A genome-wide approach for detecting novel insertion-deletion variants of mid-range size Runs of Homozygosity: Association with Coronary Artery Disease and Gene Expression in Monocytes and Macrophages Clinical and biological characterization of patients with low (0.1-2%) JAK2V617F allele burden at diagnosis Similarities and differences between exome sequences found in a variety of tissues from the same individual The role of epigenetic mechanisms and processes in autoimmune disorders

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Detectable clonal mosaicism from birth to old age and its relationship to cancer

http://www.wikidata.org/entity/Q28385149

description

2012 nî lūn-bûn

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2012 թուականի Մայիսին հրատարակուած գիտական յօդուած

@hyw

2012 թվականի մայիսին հրատարակված գիտական հոդված

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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name

Detectable clonal mosaicism from birth to old age and its relationship to cancer

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Detectable clonal mosaicism from birth to old age and its relationship to cancer

@en

Detectable clonal mosaicism from birth to old age and its relationship to cancer

@nl

type

label

Detectable clonal mosaicism from birth to old age and its relationship to cancer

@ast

Detectable clonal mosaicism from birth to old age and its relationship to cancer

@en

Detectable clonal mosaicism from birth to old age and its relationship to cancer

@nl

prefLabel

Detectable clonal mosaicism from birth to old age and its relationship to cancer

@ast

Detectable clonal mosaicism from birth to old age and its relationship to cancer

@en

Detectable clonal mosaicism from birth to old age and its relationship to cancer

@nl

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Nature Genetics

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Detectable clonal mosaicism from birth to old age and its relationship to cancer

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Alan F Scott

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Anastasia Wise

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Andrew Crenshaw

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Caitlin P McHugh

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Cathy C Laurie

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Cecelia A Laurie

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Chris Amos

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Cynthia Regnier

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Daniel B Mirel

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David M Levine

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P2860

Detectable clonal mosaicism and its relationship to aging and cancer

Genomic aberrations and survival in chronic lymphocytic leukemia

The clonal evolution of tumor cell populations

Linking functional decline of telomeres, mitochondria and stem cells during ageing

Copy-number variation and association studies of human disease

Origins and functional impact of copy number variation in the human genome

Comprehensive assessment of array-based platforms and calling algorithms for detection of copy number variants

The Gene, Environment Association Studies consortium (GENEVA): maximizing the knowledge obtained from GWAS by collaboration across studies of multiple conditions

PennCNV: an integrated hidden Markov model designed for high-resolution copy number variation detection in whole-genome SNP genotyping data

Circular binary segmentation for the analysis of array-based DNA copy number data

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642-50

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scholarly article

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855592

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10.1038/NG.2271

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6

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44

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Stephen Chanock

Loic Le Marchand

Maria Teresa Landi

Eleanor Feingold

Stephanie M. Gogarten

M Geoffrey Hayes

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2012-05-06T00:00:00Z

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224914053

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22561516

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3366033

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