Age-related mutations associated with clonal hematopoietic expansion and malignancies - Test2 - elhamkhani - TriplyDB

Age-related mutations associated with clonal hematopoietic expansion and malignancies

Age-related mutations associated with clonal hematopoietic expansion and malignancies

http://www.wikidata.org/entity/Q28387160

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Aging of hematopoietic stem cells: DNA damage and mutations?Recent advances in understanding myelofibrosis and essential thrombocythemia Molecular and Cellular Mechanisms of Myelodysplastic Syndrome: Implications on Targeted Therapy Underground Adaptation to a Hostile Environment: Acute Myeloid Leukemia vs. Natural Killer Cells Rationale for revision and proposed changes of the WHO diagnostic criteria for polycythemia vera, essential thrombocythemia and primary myelofibrosis Molecular landscape of acute myeloid leukemia in younger adults and its clinical relevance Inflammation as a Driver of Clonal Evolution in Myeloproliferative Neoplasm Missing Cells: Pathophysiology, Diagnosis, and Management of (Pan)Cytopenia in Childhood Molecular Testing in Myelodysplastic Syndromes for the Practicing Oncologist: Will the Progress Fulfill the Promise?How cell death shapes cancer IDH2R172 mutations define a unique subgroup of patients with angioimmunoblastic T-cell lymphoma.Genomic Classification and Prognosis in Acute Myeloid Leukemia.Female chromosome X mosaicism is age-related and preferentially affects the inactivated X chromosome Role of TET enzymes in DNA methylation, development, and cancer New insights into the generation and role of de novo mutations in health and disease Inflamm-Aging of Hematopoiesis, Hematopoietic Stem Cells, and the Bone Marrow Microenvironment Clonal hematopoiesis in acquired aplastic anemia Advancing the Minimal Residual Disease Concept in Acute Myeloid Leukemia Post-zygotic Point Mutations Are an Underrecognized Source of De Novo Genomic Variation Aging-Induced Stem Cell Mutations as Drivers for Disease and Cancer Stochastic modeling reveals an evolutionary mechanism underlying elevated rates of childhood leukemia Leukemia-associated somatic mutations drive distinct patterns of age-related clonal hemopoiesis Myelodysplastic Syndromes Diagnosis: What Is the Role of Molecular Testing?Integrated Multiregional Analysis Proposing a New Model of Colorectal Cancer Evolution The landscape of somatic mutations in protein coding genes in apparently benign human tissues carries signatures of relaxed purifying selection Identification of Circulating Tumor DNA for the Early Detection of Small-cell Lung Cancer Clonal hematopoiesis of indeterminate potential and its distinction from myelodysplastic syndromes Germ line variants predispose to both JAK2 V617F clonal hematopoiesis and myeloproliferative neoplasms Mosaic loss of chromosome Y is associated with common variation near TCL1A MDS-associated somatic mutations and clonal hematopoiesis are common in idiopathic cytopenias of undetermined significance Aging-associated inflammation promotes selection for adaptive oncogenic events in B cell progenitors Ultra-deep sequencing detects ovarian cancer cells in peritoneal fluid and reveals somatic TP53 mutations in noncancerous tissues Accumulation of DNA damage in the aged hematopoietic stem cell compartment Diffuse Large B-cell Lymphoma in the elderly: standard treatment and new perspectives.The ageing genome, clonal mosaicism and chronic disease.Recent advances in the understanding of myelodysplastic syndromes with ring sideroblasts.Precision medicine at Memorial Sloan Kettering Cancer Center: clinical next-generation sequencing enabling next-generation targeted therapy trials.A data-driven network model of primary myelofibrosis: transcriptional and post-transcriptional alterations in CD34+ cells.Impact of TP53 mutation variant allele frequency on phenotype and outcomes in myelodysplastic syndromes.Genetic predisposition to myelodysplastic syndrome and acute myeloid leukemia in children and young adults.

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P2860

Age-related mutations associated with clonal hematopoietic expansion and malignancies

http://www.wikidata.org/entity/Q28387160

description

2014 nî lūn-bûn

@nan

2014 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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name

Age-related mutations associated with clonal hematopoietic expansion and malignancies

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Age-related mutations associated with clonal hematopoietic expansion and malignancies

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Age-related mutations associated with clonal hematopoietic expansion and malignancies

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type

label

Age-related mutations associated with clonal hematopoietic expansion and malignancies

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Age-related mutations associated with clonal hematopoietic expansion and malignancies

@en

Age-related mutations associated with clonal hematopoietic expansion and malignancies

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prefLabel

Age-related mutations associated with clonal hematopoietic expansion and malignancies

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Age-related mutations associated with clonal hematopoietic expansion and malignancies

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Age-related mutations associated with clonal hematopoietic expansion and malignancies

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Nature Medicine

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Age-related mutations associated with clonal hematopoietic expansion and malignancies

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Bradley A Ozenberger

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Charles Lu

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Daniel C Link

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Feng Chen

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Heather K Schmidt

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Jiayin Wang

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John F Dipersio

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John S Welch

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Joshua F McMichael

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Kimberly J Johnson

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P2860

Cancer genome landscapes

Detectable clonal mosaicism and its relationship to aging and cancer

Somatic CALR mutations in myeloproliferative neoplasms with nonmutated JAK2

The genetic basis of early T-cell precursor acute lymphoblastic leukaemia.

VarScan 2: somatic mutation and copy number alteration discovery in cancer by exome sequencing

Fast and accurate short read alignment with Burrows-Wheeler transform

DNMT3A Mutations in Acute Myeloid Leukemia

The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data

Cancer statistics, 2013

Mutational landscape and significance across 12 major cancer types

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855606

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10.1038/NM.3733

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12

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20

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Christopher A. Miller

Venkata Yellapantula

Michael D McLellan

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2014-12-01T00:00:00Z

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