Age-related mutations associated with clonal hematopoietic expansion and malignancies
about
Aging of hematopoietic stem cells: DNA damage and mutations?Recent advances in understanding myelofibrosis and essential thrombocythemiaMolecular and Cellular Mechanisms of Myelodysplastic Syndrome: Implications on Targeted TherapyUnderground Adaptation to a Hostile Environment: Acute Myeloid Leukemia vs. Natural Killer CellsRationale for revision and proposed changes of the WHO diagnostic criteria for polycythemia vera, essential thrombocythemia and primary myelofibrosisMolecular landscape of acute myeloid leukemia in younger adults and its clinical relevanceInflammation as a Driver of Clonal Evolution in Myeloproliferative NeoplasmMissing Cells: Pathophysiology, Diagnosis, and Management of (Pan)Cytopenia in ChildhoodMolecular Testing in Myelodysplastic Syndromes for the Practicing Oncologist: Will the Progress Fulfill the Promise?How cell death shapes cancerIDH2R172 mutations define a unique subgroup of patients with angioimmunoblastic T-cell lymphoma.Genomic Classification and Prognosis in Acute Myeloid Leukemia.Female chromosome X mosaicism is age-related and preferentially affects the inactivated X chromosomeRole of TET enzymes in DNA methylation, development, and cancerNew insights into the generation and role of de novo mutations in health and diseaseInflamm-Aging of Hematopoiesis, Hematopoietic Stem Cells, and the Bone Marrow MicroenvironmentClonal hematopoiesis in acquired aplastic anemiaAdvancing the Minimal Residual Disease Concept in Acute Myeloid LeukemiaPost-zygotic Point Mutations Are an Underrecognized Source of De Novo Genomic VariationAging-Induced Stem Cell Mutations as Drivers for Disease and CancerStochastic modeling reveals an evolutionary mechanism underlying elevated rates of childhood leukemiaLeukemia-associated somatic mutations drive distinct patterns of age-related clonal hemopoiesisMyelodysplastic Syndromes Diagnosis: What Is the Role of Molecular Testing?Integrated Multiregional Analysis Proposing a New Model of Colorectal Cancer EvolutionThe landscape of somatic mutations in protein coding genes in apparently benign human tissues carries signatures of relaxed purifying selectionIdentification of Circulating Tumor DNA for the Early Detection of Small-cell Lung CancerClonal hematopoiesis of indeterminate potential and its distinction from myelodysplastic syndromesGerm line variants predispose to both JAK2 V617F clonal hematopoiesis and myeloproliferative neoplasmsMosaic loss of chromosome Y is associated with common variation near TCL1AMDS-associated somatic mutations and clonal hematopoiesis are common in idiopathic cytopenias of undetermined significanceAging-associated inflammation promotes selection for adaptive oncogenic events in B cell progenitorsUltra-deep sequencing detects ovarian cancer cells in peritoneal fluid and reveals somatic TP53 mutations in noncancerous tissuesAccumulation of DNA damage in the aged hematopoietic stem cell compartmentDiffuse Large B-cell Lymphoma in the elderly: standard treatment and new perspectives.The ageing genome, clonal mosaicism and chronic disease.Recent advances in the understanding of myelodysplastic syndromes with ring sideroblasts.Precision medicine at Memorial Sloan Kettering Cancer Center: clinical next-generation sequencing enabling next-generation targeted therapy trials.A data-driven network model of primary myelofibrosis: transcriptional and post-transcriptional alterations in CD34+ cells.Impact of TP53 mutation variant allele frequency on phenotype and outcomes in myelodysplastic syndromes.Genetic predisposition to myelodysplastic syndrome and acute myeloid leukemia in children and young adults.
P2860
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P2860
Age-related mutations associated with clonal hematopoietic expansion and malignancies
description
2014 nî lūn-bûn
@nan
2014 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Age-related mutations associated with clonal hematopoietic expansion and malignancies
@ast
Age-related mutations associated with clonal hematopoietic expansion and malignancies
@en
Age-related mutations associated with clonal hematopoietic expansion and malignancies
@nl
type
label
Age-related mutations associated with clonal hematopoietic expansion and malignancies
@ast
Age-related mutations associated with clonal hematopoietic expansion and malignancies
@en
Age-related mutations associated with clonal hematopoietic expansion and malignancies
@nl
prefLabel
Age-related mutations associated with clonal hematopoietic expansion and malignancies
@ast
Age-related mutations associated with clonal hematopoietic expansion and malignancies
@en
Age-related mutations associated with clonal hematopoietic expansion and malignancies
@nl
P2093
P2860
P50
P3181
P356
P1433
P1476
Age-related mutations associated with clonal hematopoietic expansion and malignancies
@en
P2093
Bradley A Ozenberger
Charles Lu
Daniel C Link
Heather K Schmidt
Jiayin Wang
John F Dipersio
John S Welch
Joshua F McMichael
Kimberly J Johnson
P2860
P2888
P304
P3181
P356
10.1038/NM.3733
P407
P577
2014-12-01T00:00:00Z