A gene optimization strategy that enhances production of fully functional P-glycoprotein in Pichia pastoris
about
Strategies of bacterial over expression of membrane transporters relevant in human health: the successful case of the three members of OCTN subfamilyStructures of P-glycoprotein reveal its conformational flexibility and an epitope on the nucleotide-binding domainA simple and accurate two-step long DNA sequences synthesis strategy to improve heterologous gene expression in pichiaDetergent screening and purification of the human liver ABC transporters BSEP (ABCB11) and MDR3 (ABCB4) expressed in the yeast Pichia pastorisDirected evolution of P-glycoprotein cysteines reveals site-specific, non-conservative substitutions that preserve multidrug resistance.Codon optimization significantly improves the expression level of a keratinase gene in Pichia pastoris.Distinct conformational spectrum of homologous multidrug ABC transporters.Snapshots of ligand entry, malleable binding and induced helical movement in P-glycoprotein.New developments of RNAi in Paracoccidioides brasiliensis: prospects for high-throughput, genome-wide, functional genomics.Identification of a Cryptic Bacterial Promoter in Mouse (mdr1a) P-Glycoprotein cDNA.Novel methods to optimize gene and statistic test for evaluation - an application for Escherichia coli.Unravelling the complex drug-drug interactions of the cardiovascular drugs, verapamil and digoxin, with P-glycoprotein.P-glycoprotein is fully active after multiple tryptophan substitutionsGlobal marine pollutants inhibit P-glycoprotein: Environmental levels, inhibitory effects, and cocrystal structureAssociation/dissociation of the nucleotide-binding domains of the ATP-binding cassette protein MsbA measured during continuous hydrolysisHuman-Mouse Chimeras with Normal Expression and Function Reveal That Major Domain Swapping Is Tolerated by P-Glycoprotein (ABCB1).Increased dosage of AOX1 promoter-regulated expression cassettes leads to transcription attenuation of the methanol metabolism in Pichia pastorisOptimization of Recombinant Expression of Synthetic Bacterial Phytase in Pichia pastoris Using Response Surface MethodologyMolecular optimization of rabies virus glycoprotein expression in Pichia pastoris.Droplet digital PCR-aided screening and characterization of Pichia pastoris multiple gene copy strains.Cooperativity between verapamil and ATP bound to the efflux transporter P-glycoprotein.Characterization and high level expression of acidic endoglucanase in Pichia pastoris.Expression, purification, and immunogenic characterization of Epstein-Barr virus recombinant EBNA1 protein in Pichia pastoris.Polymer Nanodiscs: Discoidal Amphiphilic Block Copolymer Membranes as a New Platform for Membrane Proteins.Substrate-induced conformational changes in the nucleotide-binding domains of lipid bilayer-associated P-glycoprotein during ATP hydrolysis.Biotechnological exploitation of Tetrapisispora phaffii killer toxin: heterologous production in Komagataella phaffii (Pichia pastoris).Bioprocess development for extracellular production of recombinant human interleukin-3 (hIL-3) in Pichia pastoris.The phytotoxic activity of the cerato-platanin BcSpl1 resides in a two-peptide motif on the protein surface.
P2860
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P2860
A gene optimization strategy that enhances production of fully functional P-glycoprotein in Pichia pastoris
description
2011 nî lūn-bûn
@nan
2011 թուականին հրատարակուած գիտական յօդուած
@hyw
2011 թվականին հրատարակված գիտական հոդված
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2011年の論文
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2011年論文
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2011年論文
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2011年論文
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2011年論文
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2011年論文
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2011年论文
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name
A gene optimization strategy t ...... lycoprotein in Pichia pastoris
@ast
A gene optimization strategy t ...... lycoprotein in Pichia pastoris
@en
A gene optimization strategy t ...... lycoprotein in Pichia pastoris
@nl
type
label
A gene optimization strategy t ...... lycoprotein in Pichia pastoris
@ast
A gene optimization strategy t ...... lycoprotein in Pichia pastoris
@en
A gene optimization strategy t ...... lycoprotein in Pichia pastoris
@nl
prefLabel
A gene optimization strategy t ...... lycoprotein in Pichia pastoris
@ast
A gene optimization strategy t ...... lycoprotein in Pichia pastoris
@en
A gene optimization strategy t ...... lycoprotein in Pichia pastoris
@nl
P2093
P2860
P3181
P1433
P1476
A gene optimization strategy t ...... lycoprotein in Pichia pastoris
@en
P2093
Andrew Ward
Christie G Brouillette
Douglas J Swartz
Ellen Hildebrandt
Geoffrey Chang
Ina L Urbatsch
Irina I Protasevich
Jiangping Bai
Patina M Harrell
P2860
P304
P3181
P356
10.1371/JOURNAL.PONE.0022577
P407
P577
2011-08-03T00:00:00Z