Failure of megakaryopoiesis and arrested erythropoiesis in mice lacking the GATA-1 transcriptional cofactor FOG
about
hFOG-2, a novel zinc finger protein, binds the co-repressor mCtBP2 and modulates GATA-mediated activationFamilial dyserythropoietic anaemia and thrombocytopenia due to an inherited mutation in GATA1Potentiation of GATA-2 activity through interactions with the promyelocytic leukemia protein (PML) and the t(15;17)-generated PML-retinoic acid receptor alpha oncoproteinGATA proteins work together with friend of GATA (FOG) and C-terminal binding protein (CTBP) co-regulators to control adipogenesisKnockdown of ZNF268, which is transcriptionally downregulated by GATA-1, promotes proliferation of K562 cellsGATA-1 forms distinct activating and repressive complexes in erythroid cellsX-linked thrombocytopenia with thalassemia from a mutation in the amino finger of GATA-1 affecting DNA binding rather than FOG-1 interactionIdentification of a cytokine-induced antiapoptotic molecule anamorsin essential for definitive hematopoiesisTranscriptional cofactors of the FOG family interact with GATA proteins by means of multiple zinc fingersZinc fingers as protein recognition motifs: structural basis for the GATA-1/friend of GATA interactionIdentification of the human eosinophil lineage-committed progenitor: revision of phenotypic definition of the human common myeloid progenitorAbnormalities of GATA-1 in megakaryocytes from patients with idiopathic myelofibrosisMolecular cloning of FOG-2: a modulator of transcription factor GATA-4 in cardiomyocytesMaster regulatory GATA transcription factors: mechanistic principles and emerging links to hematologic malignanciesPrimitive and definitive erythropoiesis in mammalsPluripotent stem cells reveal the developmental biology of human megakaryocytes and provide a source of platelets for clinical applicationHematopoietic overexpression of FOG1 does not affect B-cells but reduces the number of circulating eosinophilsCharacterization of the conserved interaction between GATA and FOG family proteinsThe Identification and Structure of an N-Terminal PR Domain Show that FOG1 Is a Member of the PRDM Family of ProteinsAbsence of mutations in the HoxA10, HoxA11 and HoxD11 nucleotide coding sequences in thrombocytopenia with absent radius syndromeDefects of the heart, eye, and megakaryocytes in peroxisome proliferator activator receptor-binding protein (PBP) null embryos implicate GATA family of transcription factorsErythro-megakaryocytic transcription factors associated with hereditary anemiaAutophagy driven by a master regulator of hematopoiesisFOG-1 recruits the NuRD repressor complex to mediate transcriptional repression by GATA-1.GATA switches as developmental driversAnalysis of disease-causing GATA1 mutations in murine gene complementation systemsMaturation stage-specific regulation of megakaryopoiesis by pointed-domain Ets proteinsSox6 is necessary for efficient erythropoiesis in adult mice under physiological and anemia-induced stress conditionsGenome-wide ENU mutagenesis in combination with high density SNP analysis and exome sequencing provides rapid identification of novel mouse models of developmental diseaseTranslational isoforms of FOG1 regulate GATA1-interacting complexesInteraction between FOG-1 and the corepressor C-terminal binding protein is dispensable for normal erythropoiesis in vivo.A classic zinc finger from friend of GATA mediates an interaction with the coiled-coil of transforming acidic coiled-coil 3The critical regulator of embryonic hematopoiesis, SCL, is vital in the adult for megakaryopoiesis, erythropoiesis, and lineage choice in CFU-S12An alternative transcript of the FOG-2 gene encodes a FOG-2 isoform lacking the FOG repression motifDefective neural tube closure and anteroposterior patterning in mice lacking the LIM protein LMO4 or its interacting partner Deaf-1FOG-1-mediated recruitment of NuRD is required for cell lineage re-enforcement during haematopoiesisEndothelial lineage-mediated loss of the GATA cofactor Friend of GATA 1 impairs cardiac developmentFOG-2: A novel GATA-family cofactor related to multitype zinc-finger proteins Friend of GATA-1 and U-shaped.The role and regulation of friend of GATA-1 (FOG-1) during blood development in the zebrafish.The megakaryocyte lineage originates from hemangioblast precursors and is an integral component both of primitive and of definitive hematopoiesis
P2860
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P2860
Failure of megakaryopoiesis and arrested erythropoiesis in mice lacking the GATA-1 transcriptional cofactor FOG
description
1998 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 1998
@ast
im April 1998 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1998/04/15)
@sk
vědecký článek publikovaný v roce 1998
@cs
wetenschappelijk artikel (gepubliceerd op 1998/04/15)
@nl
наукова стаття, опублікована у квітні 1998
@uk
научни чланак (објављен 1998/04/15)
@sr
name
Failure of megakaryopoiesis an ...... 1 transcriptional cofactor FOG
@ast
Failure of megakaryopoiesis an ...... 1 transcriptional cofactor FOG
@en
Failure of megakaryopoiesis an ...... 1 transcriptional cofactor FOG
@nl
type
label
Failure of megakaryopoiesis an ...... 1 transcriptional cofactor FOG
@ast
Failure of megakaryopoiesis an ...... 1 transcriptional cofactor FOG
@en
Failure of megakaryopoiesis an ...... 1 transcriptional cofactor FOG
@nl
prefLabel
Failure of megakaryopoiesis an ...... 1 transcriptional cofactor FOG
@ast
Failure of megakaryopoiesis an ...... 1 transcriptional cofactor FOG
@en
Failure of megakaryopoiesis an ...... 1 transcriptional cofactor FOG
@nl
P2093
P2860
P356
P1433
P1476
Failure of megakaryopoiesis an ...... 1 transcriptional cofactor FOG
@en
P2093
A. P. Tsang
S. H. Orkin
Y. Fujiwara
P2860
P304
P356
10.1101/GAD.12.8.1176
P577
1998-04-15T00:00:00Z