Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation
about
The epigenetic landscape of acute myeloid leukemiaASXL1 mutations promote myeloid transformation through loss of PRC2-mediated gene repressionTET2 and TET3 regulate GlcNAcylation and H3K4 methylation through OGT and SET1/COMPASSMutations in isocitrate dehydrogenase 1 and 2 occur frequently in intrahepatic cholangiocarcinomas and share hypermethylation targets with glioblastomasAcute depletion of Tet1-dependent 5-hydroxymethylcytosine levels impairs LIF/Stat3 signaling and results in loss of embryonic stem cell identityWilms tumor 1 mutations in the pathogenesis of acute myeloid leukemiaEpigenetic regulators and their impact on therapy in acute myeloid leukemiaDNA Methylation in Skeletal Muscle Stem Cell Specification, Proliferation, and Differentiation.Epigenetic modulators, modifiers and mediators in cancer aetiology and progressionCytogenetic and molecular abnormalities in chronic myelomonocytic leukemiaEpigenetic Control of Haematopoietic Stem Cell Aging and Its Clinical ImplicationsFunctions of TET Proteins in Hematopoietic TransformationMechanisms and functions of Tet protein-mediated 5-methylcytosine oxidationThe Mechanisms of Generation, Recognition, and Erasure of DNA 5-Methylcytosine and Thymine OxidationsEngineering mouse models with myelodysplastic syndrome human candidate genes; how relevant are they?Acute myeloid leukaemia: a paradigm for the clonal evolution of cancer?Active DNA demethylation in post-mitotic neurons: a reason for optimismNew answers to old questions from genome-wide maps of DNA methylation in hematopoietic cellsCytosine modifications in neurodevelopment and diseases5-Hydroxymethylcytosine: A new player in brain disorders?Mechanisms of epigenetic regulation of leukemia onset and progressionConnections between TET proteins and aberrant DNA modification in cancerMyeloid malignancies: mutations, models and managementMechanism and function of oxidative reversal of DNA and RNA methylationThe TET2 interactors and their links to hematological malignanciesChromatin dynamics during cellular reprogrammingJAK2 and genomic instability in the myeloproliferative neoplasms: a case of the chicken or the egg?Epigenomics: the science of no-longer-junk DNA. Why study it in chronic kidney disease?Epigenetic regulation of hematopoietic stem cell agingLoss of function of TET2 cooperates with constitutively active KIT in murine and human models of mastocytosisTet3 CXXC Domain and Dioxygenase Activity Cooperatively Regulate Key Genes for Xenopus Eye and Neural DevelopmentNext generation sequencing of acute myeloid leukemia: influencing prognosis.Molecular-defined clonal evolution in patients with chronic myeloid leukemia independent of the BCR-ABL status.Role of TET enzymes in DNA methylation, development, and cancerDNMT3A and TET2 in the Pre-Leukemic Phase of Hematopoietic DisordersEmerging concepts of epigenetic dysregulation in hematological malignanciesEpigenetic mechanisms in heart development and diseaseDNA methylation and hydroxymethylation in stem cellsDNA hydroxymethylation profiling reveals that WT1 mutations result in loss of TET2 function in acute myeloid leukemiaWT1 recruits TET2 to regulate its target gene expression and suppress leukemia cell proliferation
P2860
Q21284742-63FF095F-E066-40CE-93B8-A6B1E1CD0F9DQ24296658-B366493E-0A97-4B1E-8193-C6AED066D841Q24312040-251D0415-4673-4D58-9AA9-F77B7F561661Q24610836-93C256E0-E70F-4BBE-9CA2-7A6ECFF659AFQ24633944-B7EC2CC5-4297-4B20-BB27-598960C25524Q26744111-B45133F6-5986-4D1A-8499-D4CF42A11C79Q26765402-9B37F9C5-D876-44A0-9EB9-3A1B41BD5AA6Q26765889-4D9B86D5-E277-4AFE-8731-49B2F68A07D4Q26766149-438CFF4A-E017-4A22-93E5-34F9B277969FQ26768600-768A75AD-F6B4-4309-90F4-7BE6AC5AA40DQ26774949-22B33348-6E60-4A40-9B17-B169B9FCFF95Q26778323-A457FD42-8BAA-4240-9ACA-2A0813DE51BCQ26823896-524D876A-874D-4FDD-B6C1-93472B7E2A42Q26824713-CE287A9C-961F-4D49-8EB3-62005A194E11Q26828777-FC48923E-5FD9-4DD8-A2C5-227531179164Q26828997-4A5F6B9E-9FAD-4150-A743-DD9448A47C8BQ26829515-182FBBA4-27F3-481D-95D3-EFDE38FC3B27Q26851510-1B80C3D1-6126-4961-BD35-1C75B3CD9FE8Q26852087-DC8CD235-94C7-4E68-B37D-36D435686C13Q26853292-23703297-5F4B-4F05-B175-29936E363AE0Q26861785-664E322F-80E0-40CA-9B97-1DEFE7F0858FQ26865671-75429C43-F138-4A35-829D-ECF463AA378DQ27000577-9FABB82D-6793-4D49-8CF3-E5C5C609DA2FQ27002361-D1ECB156-EB25-476E-9384-805212FA0064Q27002485-0BB3AF46-EEDD-4AD2-8A36-E16723AE4F79Q27003401-07F63831-35DE-401F-9298-541EFA3D770FQ27012572-E70D9994-51C7-44E6-9236-2297DF18DDC2Q27013782-9170E2EE-0CD4-4F4D-8A61-F10BCB28D29BQ27026054-9463D15D-BB91-4CCF-B039-4DF0470BAF61Q27334940-69D7960B-6B8A-4021-A1CD-8D9A223AA420Q27675385-CACEF4C6-196C-4D42-95EB-0F9E3D674DA2Q27690776-FDAB2C08-81B5-493C-B9F0-5F131096CC81Q27853066-AA2A9434-B873-440E-BA45-B71FB35F502DQ28068541-DB9749AA-B878-49D2-A556-20D239F63536Q28073970-BC23A656-61C3-4FB1-88BB-30EFEA0E1E05Q28074522-4D40E4F3-D5CB-46AC-8AFE-C3F8F1E8CC4DQ28081134-0BC76409-0D5C-4E71-A63B-1E1373951A0EQ28081499-51319AAA-C00B-4DCC-8AE7-CC05DDB277DDQ28253465-80E11577-7B92-439A-84A2-71ACA66D0460Q28255707-452B4877-6DD6-4FCE-969B-B616C0705640
P2860
Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation
description
2011 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2011
@ast
im Juli 2011 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2011/07/12)
@sk
vědecký článek publikovaný v roce 2011
@cs
wetenschappelijk artikel (gepubliceerd op 2011/07/12)
@nl
наукова стаття, опублікована в липні 2011
@uk
مقالة علمية (نشرت في 12-7-2011)
@ar
name
Tet2 loss leads to increased h ...... wal and myeloid transformation
@ast
Tet2 loss leads to increased h ...... wal and myeloid transformation
@en
Tet2 loss leads to increased h ...... wal and myeloid transformation
@nl
type
label
Tet2 loss leads to increased h ...... wal and myeloid transformation
@ast
Tet2 loss leads to increased h ...... wal and myeloid transformation
@en
Tet2 loss leads to increased h ...... wal and myeloid transformation
@nl
prefLabel
Tet2 loss leads to increased h ...... wal and myeloid transformation
@ast
Tet2 loss leads to increased h ...... wal and myeloid transformation
@en
Tet2 loss leads to increased h ...... wal and myeloid transformation
@nl
P2093
P2860
P50
P3181
P1433
P1476
Tet2 loss leads to increased h ...... wal and myeloid transformation
@en
P2093
Aparna Vasanthakumar
Ari Melnick
Delphine Ndiaye-Lobry
Iannis Aifantis
Jozef Madzo
Kelly Moran-Crusio
Linsey Reavie
P2860
P3181
P356
10.1016/J.CCR.2011.06.001
P577
2011-07-12T00:00:00Z