Unsuspected role for the T-cell leukemia protein SCL/tal-1 in vascular development
about
A critical role for the transcription factor Scl in platelet production during stress thrombopoiesisTargets of the Tal1 transcription factor in erythrocytes: E2 ubiquitin conjugase regulation by Tal1Oncogenic transcription factor Evi1 regulates hematopoietic stem cell proliferation through GATA-2 expressionEssential role for Galpha13 in endothelial cells during embryonic developmentMegakaryocyte biology and related disordersTranscriptional regulation of the stem cell leukemia gene (SCL)--comparative analysis of five vertebrate SCL lociHematopoiesis: from start to immune reconstitution potentialEarly endocardial morphogenesis requires Scl/Tal1Analysis of vertebrate SCL loci identifies conserved enhancersIdentification of a novel transcription factor, ELYS, expressed predominantly in mouse foetal haematopoietic tissuesDisordered T-cell development and T-cell malignancies in SCL LMO1 double-transgenic mice: parallels with E2A-deficient miceDifferentiating embryonal stem cells are a rich source of haemopoietic gene products and suggest erythroid preconditioning of primitive haemopoietic stem cellsSCL/tal-1-dependent process determines a competence to select the definitive hematopoietic lineage prior to endothelial differentiationThe DNA binding activity of TAL-1 is not required to induce leukemia/lymphoma in miceThe critical regulator of embryonic hematopoiesis, SCL, is vital in the adult for megakaryopoiesis, erythropoiesis, and lineage choice in CFU-S12Immune-related zinc finger gene ZFAT is an essential transcriptional regulator for hematopoietic differentiation in blood islandsMef2C is a lineage-restricted target of Scl/Tal1 and regulates megakaryopoiesis and B-cell homeostasisMolecular hallmarks of endogenous chromatin complexes containing master regulators of hematopoiesisThe essential haematopoietic transcription factor Scl is also critical for neuronal developmentSCL/Tal-1 is essential for hematopoietic commitment of the hemangioblast but not for its developmentCombinatorial effects of Flk1 and Tal1 on vascular and hematopoietic development in the mouseEndothelial lineage-mediated loss of the GATA cofactor Friend of GATA 1 impairs cardiac developmentAngiopoietin-2 is a direct transcriptional target of TAL1, LYL1 and LMO2 in endothelial cellsA transgene-assisted genetic screen identifies essential regulators of vascular development in vertebrate embryosVascular remodeling of the mouse yolk sac requires hemodynamic force.Distinct functions for different scl isoforms in zebrafish primitive and definitive hematopoiesisGene expression analysis of embryonic stem cells expressing VE-cadherin (CD144) during endothelial differentiationSegregation of the embryonic vascular and hemopoietic systems.Chromatin immunoselection defines a TAL-1 target geneDirect induction of haematoendothelial programs in human pluripotent stem cells by transcriptional regulators.The erythrocyte viral trap: transgenic expression of viral receptor on erythrocytes attenuates coxsackievirus B infectionA GATA box in the GATA-1 gene hematopoietic enhancer is a critical element in the network of GATA factors and sites that regulate this gene.The role of FGF and VEGF in angioblast induction and migration during vascular development.RapGEF2 is essential for embryonic hematopoiesis but dispensable for adult hematopoiesis.Transcriptional link between blood and bone: the stem cell leukemia gene and its +19 stem cell enhancer are active in bone cellsDynamic shifts in occupancy by TAL1 are guided by GATA factors and drive large-scale reprogramming of gene expression during hematopoiesis.Molecular and developmental biology of the hemangioblastHematopoietic stem cells and their precursors: developmental diversity and lineage relationships.Transcriptional control of endothelial cell development.Prdm6 is essential for cardiovascular development in vivo
P2860
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P2860
Unsuspected role for the T-cell leukemia protein SCL/tal-1 in vascular development
description
1998 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 1998
@ast
im Februar 1998 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1998/02/15)
@sk
vědecký článek publikovaný v roce 1998
@cs
wetenschappelijk artikel (gepubliceerd op 1998/02/15)
@nl
наукова стаття, опублікована в лютому 1998
@uk
مقالة علمية (نشرت في 15-2-1998)
@ar
name
Unsuspected role for the T-cell leukemia protein SCL/tal-1 in vascular development
@ast
Unsuspected role for the T-cell leukemia protein SCL/tal-1 in vascular development
@en
Unsuspected role for the T-cell leukemia protein SCL/tal-1 in vascular development
@nl
type
label
Unsuspected role for the T-cell leukemia protein SCL/tal-1 in vascular development
@ast
Unsuspected role for the T-cell leukemia protein SCL/tal-1 in vascular development
@en
Unsuspected role for the T-cell leukemia protein SCL/tal-1 in vascular development
@nl
prefLabel
Unsuspected role for the T-cell leukemia protein SCL/tal-1 in vascular development
@ast
Unsuspected role for the T-cell leukemia protein SCL/tal-1 in vascular development
@en
Unsuspected role for the T-cell leukemia protein SCL/tal-1 in vascular development
@nl
P2093
P2860
P356
P1433
P1476
Unsuspected role for the T-cell leukemia protein SCL/tal-1 in vascular development
@en
P2093
J. E. Visvader
S. H. Orkin
Y. Fujiwara
P2860
P304
P356
10.1101/GAD.12.4.473
P577
1998-02-15T00:00:00Z