Sarm1, a negative regulator of innate immunity, interacts with syndecan-2 and regulates neuronal morphology
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Heparan sulfate proteoglycans: a sugar code for vertebrate development?TLR3 downregulates expression of schizophrenia gene Disc1 via MYD88 to control neuronal morphologyTbr1 haploinsufficiency impairs amygdalar axonal projections and results in cognitive abnormalityMicrotubule-based localization of a synaptic calcium-signaling complex is required for left-right neuronal asymmetry in C. elegans.SARM regulates CCL5 production in macrophages by promoting the recruitment of transcription factors and RNA polymerase II to the Ccl5 promoter.Litopenaeus vannamei sterile-alpha and armadillo motif containing protein (LvSARM) is involved in regulation of Penaeidins and antilipopolysaccharide factors.Activation of TLR3 promotes the degeneration of retinal ganglion cells by upregulating the protein levels of JNK3Hm-MyD88 and Hm-SARM: two key regulators of the neuroimmune system and neural repair in the medicinal leechX-linked juvenile retinoschisis: clinical diagnosis, genetic analysis, and molecular mechanisms.Bacillus anthracis TIR Domain-Containing Protein Localises to Cellular Microtubule Structures and Induces Autophagy.Antagonizing Neuronal Toll-like Receptor 2 Prevents Synucleinopathy by Activating Autophagy.T-cell death following immune activation is mediated by mitochondria-localized SARM.Activation of the innate signaling molecule MAVS by bunyavirus infection upregulates the adaptor protein SARM1, leading to neuronal death.Sarm1-mediated axon degeneration requires both SAM and TIR interactionsSARM1 and TRAF6 bind to and stabilize PINK1 on depolarized mitochondria.A Toll receptor-FoxO pathway represses Pavarotti/MKLP1 to promote microtubule dynamics in motoneurons.AIM 2 inflammasomes regulate neuronal morphology and influence anxiety and memory in miceSema4D localizes to synapses and regulates GABAergic synapse development as a membrane-bound molecule in the mammalian hippocampus.MAPK signaling promotes axonal degeneration by speeding the turnover of the axonal maintenance factor NMNAT2.Sarm1 deficiency impairs synaptic function and leads to behavioral deficits, which can be ameliorated by an mGluR allosteric modulator.Resveratrol inhibits the TRIF-dependent pathway by upregulating sterile alpha and armadillo motif protein, contributing to anti-inflammatory effects after respiratory syncytial virus infection.Innate immune response to La Crosse virus infection.Asymmetric neural development in the Caenorhabditis elegans olfactory system.Wallerian degeneration: an emerging axon death pathway linking injury and disease.Signaling mechanisms regulating Wallerian degeneration.Innate immune responses regulate morphogenesis and degeneration: roles of Toll-like receptors and Sarm1 in neurons.Toll-like receptors as developmental tools that regulate neurogenesis during development: an update.Axon Self-Destruction: New Links among SARM1, MAPKs, and NAD+ Metabolism.Beyond TLR Signaling—The Role of SARM in Antiviral Immune Defense, Apoptosis & Development.TRIF-dependent TLR signaling, its functions in host defense and inflammation, and its potential as a therapeutic target.Axonal Degeneration during Aging and Its Functional Role in Neurodegenerative DisordersPathological axonal death through a MAPK cascade that triggers a local energy deficit.Prevention of vincristine-induced peripheral neuropathy by genetic deletion of SARM1 in mice.Heparan Sulfate Proteoglycans as Emerging Players in Synaptic Specificity.Neuronally-expressed Sarm1 regulates expression of inflammatory and antiviral cytokines in brains.Hypertension Accelerates Alzheimer's Disease-Related Pathologies in Pigs and 3xTg Mice.Role of SARM1 and DR6 in retinal ganglion cell axonal and somal degeneration following axonal injury.Endosomal TLR3, TLR7, and TLR8 control neuronal morphology through different transcriptional programs.
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P2860
Sarm1, a negative regulator of innate immunity, interacts with syndecan-2 and regulates neuronal morphology
description
2011 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մայիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2011
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im Mai 2011 veröffentlichter wissenschaftlicher Artikel
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scientific journal article
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vedecký článok (publikovaný 2011/05/16)
@sk
vědecký článek publikovaný v roce 2011
@cs
wetenschappelijk artikel (gepubliceerd op 2011/05/16)
@nl
наукова стаття, опублікована в травні 2011
@uk
مقالة علمية (نشرت في 16-5-2011)
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name
Sarm1, a negative regulator of ...... regulates neuronal morphology
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Sarm1, a negative regulator of ...... regulates neuronal morphology
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Sarm1, a negative regulator of ...... regulates neuronal morphology
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type
label
Sarm1, a negative regulator of ...... regulates neuronal morphology
@ast
Sarm1, a negative regulator of ...... regulates neuronal morphology
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Sarm1, a negative regulator of ...... regulates neuronal morphology
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prefLabel
Sarm1, a negative regulator of ...... regulates neuronal morphology
@ast
Sarm1, a negative regulator of ...... regulates neuronal morphology
@en
Sarm1, a negative regulator of ...... regulates neuronal morphology
@nl
P2093
P2860
P3181
P356
P1476
Sarm1, a negative regulator of ...... regulates neuronal morphology
@en
P2093
Chia-Wen Lin
Chiung-Ya Chen
Chiung-Ying Chang
Si-Tse Jiang
Yi-Ping Hsueh
P2860
P304
P3181
P356
10.1083/JCB.201008050
P407
P577
2011-05-16T00:00:00Z