Two-repeat human telomeric d(TAGGGTTAGGGT) sequence forms interconverting parallel and antiparallel G-quadruplexes in solution: distinct topologies, thermodynamic properties, and folding/unfolding kinetics

Two-repeat human telomeric d(TAGGGTTAGGGT) sequence forms interconverting parallel and antiparallel G-quadruplexes in solution: distinct topologies, thermodynamic properties, and folding/unfolding kinetics

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http://www.wikidata.org/entity/Q28603454

Q28603454

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Quadruplex DNA: sequence, topology and structure Highly prevalent putative quadruplex sequence motifs in human DNA Vertebrate telomere repeat DNAs favor external loop propeller quadruplex structures in the presence of high concentrations of potassium.Kinetics of tetramolecular quadruplexes Covalent ligation studies on the human telomere quadruplex.Guanine tetraplex topology of human telomere DNA is governed by the number of (TTAGGG) repeats Not so crystal clear: the structure of the human telomere G-quadruplex in solution differs from that present in a crystal Facilitation of a structural transition in the polypurine/polypyrimidine tract within the proximal promoter region of the human VEGF gene by the presence of potassium and G-quadruplex-interactive agents.Resolution of a structural competition involving dimeric G-quadruplex and its C-rich complementary strand.Structural probes in quadruplex nucleic acid structure determination by NMR Structure of an Unprecedented G-Quadruplex Scaffold in the Human c-kit Promoter Structure of a human telomeric DNA sequence stabilized by 8-bromoguanosine substitutions, as determined by NMR in a K+ solution Structure of the Hybrid-2 type intramolecular human telomeric G-quadruplex in K+ solution: insights into structure polymorphism of the human telomeric sequence Structure of two intramolecular G-quadruplexes formed by natural human telomere sequences in K+ solution Structure of the Human Telomere in K + Solution: A Stable Basket-Type G-Quadruplex with Only Two G-Tetrad Layers A G-Rich Sequence within the c-kit Oncogene Promoter Forms a Parallel G-Quadruplex Having Asymmetric G-Tetrad Dynamics A crystallographic and modelling study of a human telomeric RNA (TERRA) quadruplex Solution structure of all parallel G-quadruplex formed by the oncogene RET promoter sequence Carbohydrate-DNA interactions at G-quadruplexes: folding and stability changes by attaching sugars at the 5'-end Extreme conformational diversity in human telomeric DNA Targeting human telomerase for cancer therapeutics.Putative DNA G-quadruplex formation within the promoters of Plasmodium falciparum var genes.Characterization of a K+-induced conformational switch in a human telomeric DNA oligonucleotide using 2-aminopurine fluorescence Inhibition of cancer cell migration and invasion through suppressing the Wnt1-mediating signal pathway by G-quadruplex structure stabilizers An interlocked dimeric parallel-stranded DNA quadruplex: a potent inhibitor of HIV-1 integrase.Chemistry in human telomere biology: structure, function and targeting of telomere DNA/RNA.Ball with hair: modular functionalization of highly stable G-quadruplex DNA nano-scaffolds through N2-guanine modification.Emulsified BMVC derivative induced filtration for G-quadruplex DNA structural separation Engineering the quadruplex fold: nucleoside conformation determines both folding topology and molecularity in guanine quadruplexes.Human telomeric sequence forms a hybrid-type intramolecular G-quadruplex structure with mixed parallel/antiparallel strands in potassium solution.RPA-mediated unfolding of systematically varying G-quadruplex structures.Different loop arrangements of intramolecular human telomeric (3+1) G-quadruplexes in K+ solution.G-quadruplex structures and their interaction diversity with ligands.G-quadruplexes: from guanine gels to chemotherapeutics A Personal History of Quadruplex-Small Molecule Targeting.Investigation of spectral conversion of d(TTAGGG)4 and d(TTAGGG)13 upon potassium titration by a G-quadruplex recognizer BMVC molecule.The interaction of telomeric DNA and C-myc22 G-quadruplex with 11 natural alkaloids.Sequence-specific B-DNA flexibility modulates Z-DNA formation.Interactions of a platinum-modified perylene derivative with the human telomeric G-quadruplex.Hit Identification of a Novel Dual Binder for h-telo/c-myc G-Quadruplex by a Combination of Pharmacophore Structure-Based Virtual Screening and Docking Refinement.

P2860

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P2860

Two-repeat human telomeric d(TAGGGTTAGGGT) sequence forms interconverting parallel and antiparallel G-quadruplexes in solution: distinct topologies, thermodynamic properties, and folding/unfolding kinetics

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http://www.wikidata.org/entity/Q28603454

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2003 nî lūn-bûn

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2003 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2003 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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2003年の論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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