Chemistry in human telomere biology: structure, function and targeting of telomere DNA/RNA.
about
5'-UTR RNA G-quadruplexes: translation regulation and targetingStructural Studies on Dinuclear Ruthenium(II) Complexes That Bind Diastereoselectively to an Antiparallel Folded Human Telomere SequenceComputational understanding and experimental characterization of twice-as-smart quadruplex ligands as chemical sensors of bacterial nucleotide second messengersPrefolded Synthetic G-Quartets Display Enhanced Bioinspired Properties.Selective Luminescent Labeling of DNA and RNA Quadruplexes by π-Extended Ruthenium Light-Up Probes.Pressure-dependent formation of i-motif and G-quadruplex DNA structures.Sensing telomerase: From in vitro detection to in vivo imaging.Chiral metallohelices enantioselectively target hybrid human telomeric G-quadruplex DNA.Assays for human telomerase activity: progress and prospects.Polycyclic azoniahetarenes: assessing the binding parameters of complexes between unsubstituted ligands and G-quadruplex DNA.Single-molecule investigation of G-quadruplex folds of the human telomere sequence in a protein nanocavity.Blood and dried blood spot telomere length measurement by qPCR: assay considerations.Single-molecule analysis of thymine dimer-containing G-quadruplexes formed from the human telomere sequence.G-quadruplex structures and their interaction diversity with ligands.A first-in-class and a fished out anticancer platinum compound: cis-[PtCl2(NH3)2] and cis-[PtI2(NH3)2] compared for their reactivity towards DNA model systems.Insights into how nucleotide supplements enhance the peroxidase-mimicking DNAzyme activity of the G-quadruplex/hemin system.G4LDB: a database for discovering and studying G-quadruplex ligands.Specific recognition and stabilization of monomeric and multimeric G-quadruplexes by cationic porphyrin TMPipEOPP under molecular crowding conditionsInteractions of the human telomere sequence with the nanocavity of the α-hemolysin ion channel reveal structure-dependent electrical signatures for hybrid folds.Polyethylene glycol binding alters human telomere G-quadruplex structure by conformational selection.Direct visualization of both DNA and RNA quadruplexes in human cells via an uncommon spectroscopic methodInsight into G-quadruplex-hemin DNAzyme/RNAzyme: adjacent adenine as the intramolecular species for remarkable enhancement of enzymatic activity.Preparation of 6/8/11-Amino/Chloro-Oxoisoaporphine and Group-10 Metal Complexes and Evaluation of Their in Vitro and in Vivo Antitumor ActivityIn-cell optical imaging of exogenous G-quadruplex DNA by fluorogenic ligands.Folding and unfolding pathways of the human telomeric G-quadruplex.The application of DNA and RNA G-quadruplexes to therapeutic medicines.Emerging trends in G-quadruplex biology--role in epigenetic and evolutionary events.Fluorescent probes for G-quadruplex structures.G-quadruplex structures in the human genome as novel therapeutic targets.A golden future in medicinal inorganic chemistry: the promise of anticancer gold organometallic compounds.Macrocyclic polyoxazoles as G-quadruplex ligands.Noncanonical DNA secondary structures as drug targets: the prospect of the i-motif.Targeting unimolecular G-quadruplex nucleic acids: a new paradigm for the drug discovery?Different duplex/quadruplex junctions determine the properties of anti-thrombin aptamers with mixed folding.A base-modified PNA-graphene oxide platform as a turn-on fluorescence sensor for the detection of human telomeric repeats.Porphyrin-based design of bioinspired multitarget quadruplex ligands.Targeting G-quadruplex structures with extrinsic fluorogenic dyes: promising fluorescence sensors.The tale of RNA G-quadruplex.Modelling the regulation of telomere length: the effects of telomerase and G-quadruplex stabilising drugs.An ultra-sensitive colorimetric assay for reliable visual detection of telomerase activity.
P2860
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P2860
Chemistry in human telomere biology: structure, function and targeting of telomere DNA/RNA.
description
2011 nî lūn-bûn
@nan
2011 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Chemistry in human telomere bi ...... targeting of telomere DNA/RNA.
@ast
Chemistry in human telomere bi ...... targeting of telomere DNA/RNA.
@en
type
label
Chemistry in human telomere bi ...... targeting of telomere DNA/RNA.
@ast
Chemistry in human telomere bi ...... targeting of telomere DNA/RNA.
@en
prefLabel
Chemistry in human telomere bi ...... targeting of telomere DNA/RNA.
@ast
Chemistry in human telomere bi ...... targeting of telomere DNA/RNA.
@en
P2860
P356
P1476
Chemistry in human telomere bi ...... targeting of telomere DNA/RNA.
@en
P2093
P2860
P304
P356
10.1039/C0CS00134A
P577
2011-02-07T00:00:00Z