AlkB-mediated oxidative demethylation reverses DNA damage in Escherichia coli
about
Genomic structure and expression of Jmjd6 and evolutionary analysis in the context of related JmjC domain containing proteinsALKBH4-dependent demethylation of actin regulates actomyosin dynamics.Interaction of JMJD6 with single-stranded RNADNA unwinding by ASCC3 helicase is coupled to ALKBH3-dependent DNA alkylation repair and cancer cell proliferationCrystal structure and RNA binding properties of the RNA recognition motif (RRM) and AlkB domains in human AlkB homolog 8 (ABH8), an enzyme catalyzing tRNA hypermodificationHuman ABH3 structure and key residues for oxidative demethylation to reverse DNA/RNA damageMammalian ALKBH8 possesses tRNA methyltransferase activity required for the biogenesis of multiple wobble uridine modifications implicated in translational decodingHuman AlkB homolog ABH8 Is a tRNA methyltransferase required for wobble uridine modification and DNA damage survivalALKBH5 is a mammalian RNA demethylase that impacts RNA metabolism and mouse fertilityHuman AlkB homolog 1 is a mitochondrial protein that demethylates 3-methylcytosine in DNA and RNAOxidative demethylation of 3-methylthymine and 3-methyluracil in single-stranded DNA and RNA by mouse and human FTOSpectroscopic and magnetic studies of wild-type and mutant forms of the Fe(II)- and 2-oxoglutarate-dependent decarboxylase ALKBH4Crystal structures of DNA/RNA repair enzymes AlkB and ABH2 bound to dsDNAHuman AlkB homologue 1 (ABH1) exhibits DNA lyase activity at abasic sitesHuman AlkB homologue 5 is a nuclear 2-oxoglutarate dependent oxygenase and a direct target of hypoxia-inducible factor 1α (HIF-1α)ALKBH8-mediated formation of a novel diastereomeric pair of wobble nucleosides in mammalian tRNAHuman ALKBH7 is required for alkylation and oxidation-induced programmed necrosisRepair deficient mice reveal mABH2 as the primary oxidative demethylase for repairing 1meA and 3meC lesions in DNACellular oxygen sensing: Crystal structure of hypoxia-inducible factor prolyl hydroxylase (PHD2)Biochemical characterization and DNA repair pathway interactions of Mag1-mediated base excision repair in Schizosaccharomyces pombeMutagenesis, genotoxicity, and repair of 1-methyladenine, 3-alkylcytosines, 1-methylguanine, and 3-methylthymine in alkB Escherichia coliIron-catalysed oxidation intermediates captured in a DNA repair dioxygenaseA non-heme iron-mediated chemical demethylation in DNA and RNAThe AlkB domain of mammalian ABH8 catalyzes hydroxylation of 5-methoxycarbonylmethyluridine at the wobble position of tRNAVitamin C: update on physiology and pharmacologyAlleviation of 1,N6-ethanoadenine genotoxicity by the Escherichia coli adaptive response protein AlkBBioinformatic mapping of AlkB homology domains in virusesPhylogenomic identification of five new human homologs of the DNA repair enzyme AlkBThe Role of Oxygen Sensors, Hydroxylases, and HIF in Cardiac Function and DiseaseThe Mechanisms of Generation, Recognition, and Erasure of DNA 5-Methylcytosine and Thymine OxidationsDNA glycosylases: in DNA repair and beyondThe discovery of histone demethylasesStructural basis for enzymatic excision of N1-methyladenine and N3-methylcytosine from DNAEnzymological and structural studies of the mechanism of promiscuous substrate recognition by the oxidative DNA repair enzyme AlkBStructural and Mutational Analysis of Escherichia coli AlkB Provides Insight into Substrate Specificity and DNA Damage SearchingStructure determination of DNA methylation lesions N1-meA and N3-meC in duplex DNA using a cross-linked protein-DNA systemImplications for Damage Recognition during Dpo4-Mediated Mutagenic Bypass of m1G and m3C LesionsFlavin-Induced Oligomerization in Escherichia coli Adaptive Response Protein AidBQuaternary ammonium oxidative demethylation: X-ray crystallographic, resonance Raman, and UV-visible spectroscopic analysis of a Rieske-type demethylaseStructure of human RNA N6-methyladenine demethylase ALKBH5 provides insights into its mechanisms of nucleic acid recognition and demethylation
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P2860
AlkB-mediated oxidative demethylation reverses DNA damage in Escherichia coli
description
2002 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Nature
@fr
artículu científicu espublizáu en 2002
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scientific article (publication date: 12 September 2002)
@en
wetenschappelijk artikel (gepubliceerd op 2002/09/12)
@nl
наукова стаття, опублікована у вересні 2002
@uk
مقالة علمية (نشرت في 12-9-2002)
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name
AlkB-mediated oxidative demethylation reverses DNA damage in Escherichia coli
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AlkB-mediated oxidative demethylation reverses DNA damage in Escherichia coli
@en
type
label
AlkB-mediated oxidative demethylation reverses DNA damage in Escherichia coli
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AlkB-mediated oxidative demethylation reverses DNA damage in Escherichia coli
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prefLabel
AlkB-mediated oxidative demethylation reverses DNA damage in Escherichia coli
@ast
AlkB-mediated oxidative demethylation reverses DNA damage in Escherichia coli
@en
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AlkB-mediated oxidative demethylation reverses DNA damage in Escherichia coli
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10.1038/NATURE01048
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2002-09-12T00:00:00Z
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1033807691