WLS-dependent secretion of WNT3A requires Ser209 acylation and vacuolar acidification - Test2 - elhamkhani - TriplyDB

WLS-dependent secretion of WNT3A requires Ser209 acylation and vacuolar acidification

WLS-dependent secretion of WNT3A requires Ser209 acylation and vacuolar acidification

http://www.wikidata.org/entity/Q30156041

about

Tiki1 is required for head formation via Wnt cleavage-oxidation and inactivation Wnt/beta-catenin signaling and small molecule inhibitors Wnt/β-catenin signaling in kidney injury and repair: a double-edged sword Wnt Drug Discovery: Weaving Through the Screens, Patents and Clinical Trials Notum is required for neural and head induction via Wnt deacylation, oxidation, and inactivation Identification of key residues and regions important for porcupine-mediated Wnt acylation Fatty acylation of proteins: The long and the short of it.Targeting protein lipidation in disease Wnt proteins.IC261 induces cell cycle arrest and apoptosis of human cancer cells via CK1δ/ɛ and Wnt/β-catenin independent inhibition of mitotic spindle formation.A uniform human Wnt expression library reveals a shared secretory pathway and unique signaling activities.Differential palmit(e)oylation of Wnt1 on C93 and S224 residues has overlapping and distinct consequences.Disulfide bond requirements for active Wnt ligands.Concentration-dependent effects of WNTLESS on WNT1/3A signaling.A densely interconnected genome-wide network of microRNAs and oncogenic pathways revealed using gene expression signatures V-ATPase-dependent ectodermal voltage and pH regionalization are required for craniofacial morphogenesis.PORCN moonlights in a Wnt-independent pathway that regulates cancer cell proliferation Updating the Wnt pathways.Wingless/Wnt signaling in Drosophila: the pattern and the pathway A chemical-inducible CRISPR-Cas9 system for rapid control of genome editing.Effects of hyperbaric oxygen on the osteogenic differentiation of mesenchymal stem cells Drosophila S2 cells secrete wingless on exosome-like vesicles but the wingless gradient forms independently of exosomes.Moving upstream in the war on WNTs.Mesenchymal Wnt signaling promotes formation of sternum and thoracic body wall Modulation of Wnt/β-catenin signaling and proliferation by a ferrous iron chelator with therapeutic efficacy in genetically engineered mouse models of cancer.A Comprehensive Overview of Skeletal Phenotypes Associated with Alterations in Wnt/β-catenin Signaling in Humans and Mice.Roles of N-glycosylation and lipidation in Wg secretion and signaling.Mechanism of evenness interrupted (Evi)-exosome release at synaptic boutons.Diverse chemical scaffolds support direct inhibition of the membrane-bound O-acyltransferase porcupine.SKLB-677, an FLT3 and Wnt/β-catenin signaling inhibitor, displays potent activity in models of FLT3-driven AML.Wnt addiction of genetically defined cancers reversed by PORCN inhibition.Precise regulation of porcupine activity is required for physiological Wnt signaling.Inhibiting clathrin-mediated endocytosis of the leucine-rich G protein-coupled receptor-5 diminishes cell fitness.Experimental inhibition of porcupine-mediated Wnt O-acylation attenuates kidney fibrosis.NOTUM is a potential pharmacodynamic biomarker of Wnt pathway inhibition.The Secreted Signaling Protein Wnt3 Is Associated with Membrane Domains In Vivo: A SPIM-FCS Study Stearoyl CoA desaturase is required to produce active, lipid-modified Wnt proteins.Different populations of Wnt-containing vesicles are individually released from polarized epithelial cells.Wnt secretion from epithelial cells and subepithelial myofibroblasts is not required in the mouse intestinal stem cell niche in vivo.Dissecting the Wnt secretion pathway: key questions on the modification and intracellular trafficking of Wnt proteins.

P2860

Q24338810-6F0A0683-4329-4E4B-9EA3-64F65316597F Q24597197-A63097F4-3568-43F0-B61A-C747188D9E3E Q26774029-83274803-E642-45C4-9FEB-AD60390DCF85 Q28078703-83B7FE69-4A72-4310-9933-727032FAF9F3 Q28505847-F1D6518A-84B1-43C4-8FB2-641272649304 Q28584812-5269A6AE-C80F-4BEC-B2D7-60FB8EE607A6 Q30388573-3887B235-F2A0-4EF2-9183-035B82FB9C9D Q30413212-F2888B8C-3303-4E99-A359-DB3311B3764C Q30420997-8AF9A1E0-362A-42BA-994B-0CCDBB734BDF Q30500880-3746B600-FBE8-4119-8DA5-B4B3AC3E86BF Q33589161-3B9EA80A-7AEF-4A46-BA24-BF2BFD187B5B Q34064562-E76DAAEA-5980-4B0A-A54F-37AA4CCC8374 Q34073894-C661FD46-CED9-437A-9A1C-E24FCDA12E03 Q34076258-4809AFE2-DC3A-4906-B015-21DF3A3ACDE6 Q34109828-3DCC111A-5AF8-419A-9665-476E119CDFF9 Q34200733-57CBCBE7-5C86-486A-8888-72D30C5493DE Q34235264-E076A4FE-11B7-4DD4-927A-B2A4F9F7F39D Q34360489-FC6B812B-8DF6-4F34-9BD3-86D84FA8B82B Q34378843-437744D1-1F8B-4C1B-9861-3CEF85C757F7 Q34540074-A6EE7998-077A-4625-94E9-E4AE82FF5ED0 Q35102719-777C925D-96F7-4F28-8565-8ADFEE93C156 Q35112325-5424A48D-5BB6-48FA-880A-A524FBEF385C Q35183964-B923B43D-D482-4F63-B9CD-1676B891654A Q35582565-D8CD9FCD-3372-4C74-9322-D20EBAB4DC74 Q35670541-E85FCF6C-334E-4432-AEC9-2C208C399A5C Q35755034-5A0A6683-82BA-46E0-8EB4-5D38C02D806A Q35860174-2154333D-CAFB-453A-AB97-C11CEB126526 Q35956491-9D470807-3599-4162-BF69-51E9E955124B Q36080392-1FAD2F38-72FE-4ED8-BBE9-9766A966B827 Q36205970-E78A3807-066B-4FAE-9880-3DA45A20110E Q36292664-10319436-A9B3-4FB2-8683-1C9127943F9D Q36298362-AD9D5C76-1718-4947-A650-AB3B64ECE1AB Q36301420-715D3880-16C3-4DD5-A926-9CFBE948B094 Q36805264-43A6B0BA-A8FE-47E3-876D-909EFA4EAAFC Q37022182-3E211413-E38B-4E5F-88A9-4AE05D1A04C2 Q37142139-9187E30A-394E-4AAF-AF5E-A53841F8F1E9 Q37353317-8554D9BD-212E-4813-9728-E38E06A7DF33 Q37355351-789CD272-78A5-4D99-B5D7-DF797815EAA4 Q37581662-2BF16936-AE9D-44A3-957E-6A0E3940711B Q37857909-09815173-E7AC-4F6C-967C-06A53438B234

P2860

WLS-dependent secretion of WNT3A requires Ser209 acylation and vacuolar acidification

http://www.wikidata.org/entity/Q30156041

description

2010 nî lūn-bûn

@nan

2010 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի սեպտեմբերին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

WLS-dependent secretion of WNT3A requires Ser209 acylation and vacuolar acidification

@ast

WLS-dependent secretion of WNT3A requires Ser209 acylation and vacuolar acidification

@en

type

label

WLS-dependent secretion of WNT3A requires Ser209 acylation and vacuolar acidification

@ast

WLS-dependent secretion of WNT3A requires Ser209 acylation and vacuolar acidification

@en

prefLabel

WLS-dependent secretion of WNT3A requires Ser209 acylation and vacuolar acidification

@ast

WLS-dependent secretion of WNT3A requires Ser209 acylation and vacuolar acidification

@en

P1433

Q30156041-C71063CD-D187-4361-904B-35A653932626

P1476

Q30156041-9873E9DF-73C7-4FB1-BBF6-44260F17F9BE

P2093

Q30156041-13DD8B93-430A-42A6-9B22-736271430ABB

Q30156041-27A1EC8B-3144-4AF8-9D71-42C2F54B8946

Q30156041-3335BAA5-5A3E-48CB-98BE-6A9A72D849B5

Q30156041-38CA23FD-4A27-451F-87CC-2D1971568F96

Q30156041-3D31DD3A-0DCA-453E-8F12-5CA736394A8F

Q30156041-56A48D37-2A8B-47DE-A65C-4319ED68D72D

Q30156041-8B1626E9-F1B1-4704-9E2A-52B769A1AA7F

Q30156041-91FCECA5-A063-4DFF-B683-5A10E8AB1576

Q30156041-DEAFDD56-10AF-401F-80DC-D03D4F087BAF

Q30156041-E5B39D07-46D7-44CA-9370-D39CD00E087A

P2860

Q30156041-00934C41-22E7-4EF0-8219-E4749F308714

Q30156041-06E6CE07-78E3-457B-B635-D6A1B99E58FE

Q30156041-075C0D25-E16B-408D-A515-C6B72441FAAD

Q30156041-09B6B603-E726-4520-839A-8EEBE2A69F8D

Q30156041-12A97F02-B4B3-49B1-A890-3298EEB2BF94

Q30156041-185FAF5B-188E-402F-9FC4-50F4E913A497

Q30156041-1FE7E0C3-F54D-442A-BC3A-8C5D21210D63

Q30156041-29426729-3908-4447-B00A-66D6EC9B7077

Q30156041-2EFF4861-FEAC-44AF-8338-2C4B42337609

Q30156041-32CD17A7-0B65-45E6-9792-A432899172BD

P304

Q30156041-D881EB00-AD13-4976-94D7-94EC344980E7

P31

Q30156041-CD321A10-974F-44C6-801B-4BAD85FCD1E3

P356

Q30156041-BB337C3A-26F2-45C1-964C-06E940B1C5C7

P407

Q30156041-50B41F84-89B9-42CE-BD34-2DAC6CA76772

P433

Q30156041-9C98F810-DDE8-475C-957A-E18A4B4C1DEB

P478

Q30156041-A50CA97A-9835-4CC8-91E6-CB99A36F8DED

P50

Q30156041-1C3FECDE-445B-4911-BFD7-4B5997132AC5

Q30156041-6DC4CE47-92AE-44F7-ADFF-7561BB1E7704

Q30156041-76D6B461-9298-4A24-A34D-0685C42DE8EA

Q30156041-B42722F0-E563-47C8-81E3-68F505473725

P577

Q30156041-5CD18550-F623-4505-B115-966E2D12D510

P5875

Q30156041-2A4D684E-230B-46BF-BAFA-48779F417A60

P698

Q30156041-1CCFE6A9-C20B-43BA-B2F0-6E097B0EE3E9

P932

Q30156041-8D61FBCB-96D8-4F16-A909-3894D9D6394B

P356

P1433

Journal of Cell Science

P1476

WLS-dependent secretion of WNT3A requires Ser209 acylation and vacuolar acidification

@en

P2093

C Michael Jones

http://www.w3.org/2001/XMLSchema#string

Chris M Ireland

http://www.w3.org/2001/XMLSchema#string

Claire A Canning

http://www.w3.org/2001/XMLSchema#string

Gisela P Concepcion

http://www.w3.org/2001/XMLSchema#string

Ivana Mihalek

http://www.w3.org/2001/XMLSchema#string

Jia Yu

http://www.w3.org/2001/XMLSchema#string

Jit K Cheong

http://www.w3.org/2001/XMLSchema#string

Mary Kay Harper

http://www.w3.org/2001/XMLSchema#string

Nikhil Banerjee

http://www.w3.org/2001/XMLSchema#string

Raquel C Jadulco

http://www.w3.org/2001/XMLSchema#string

P2860

The vacuolar-ATPase inhibitor bafilomycin and mutant VPS35 inhibit canonical Wnt signaling

Requirement of prorenin receptor and vacuolar H+-ATPase-mediated acidification for Wnt signaling

The retromer complex influences Wnt secretion by recycling wntless from endosomes to the trans-Golgi network

Vascular development in the retina and inner ear: control by Norrin and Frizzled-4, a high-affinity ligand-receptor pair

Wntless, a conserved membrane protein dedicated to the secretion of Wnt proteins from signaling cells

Secretion of Wnt ligands requires Evi, a conserved transmembrane protein

A molecular mechanism for the effect of lithium on development

Wnt family proteins are secreted and associated with the cell surface

Wnt signaling is regulated by endoplasmic reticulum retention

A Structural Basis for the pH-Dependent Xanthophyll Cycle in Arabidopsis thaliana

P304

3357-3367

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1242/JCS.072132

http://www.w3.org/2001/XMLSchema#string

P407

P433

Pt 19

http://www.w3.org/2001/XMLSchema#string

P478

123

http://www.w3.org/2001/XMLSchema#string

P50

David M. Virshup

Zong Hong Zhang

Charles A Veltri

P577

2010-09-07T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

46180951

http://www.w3.org/2001/XMLSchema#string

P698

20826466

http://www.w3.org/2001/XMLSchema#string

P932

2939803

http://www.w3.org/2001/XMLSchema#string