Modulation of Wnt/β-catenin signaling and proliferation by a ferrous iron chelator with therapeutic efficacy in genetically engineered mouse models of cancer.
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Wnt Drug Discovery: Weaving Through the Screens, Patents and Clinical TrialsIdentification of Cryptosporidium parvum active chemical series by Repurposing the open access malaria boxAntileishmanial Activity of Compounds Derived from the Medicines for Malaria Venture Open Access Box Against Intracellular Leishmania major AmastigotesIron and cancer: more ore to be mined.Genetic and proteomic approaches to identify cancer drug targets.CD24 Is Not Required for Tumor Initiation and Growth in Murine Breast and Prostate Cancer Models.Intracellular Iron Chelation Modulates the Macrophage Iron Phenotype with Consequences on Tumor Progression.Wnt addiction of genetically defined cancers reversed by PORCN inhibition.Iron chelation: a potential therapeutic strategy in oesophageal cancer.NOTUM is a potential pharmacodynamic biomarker of Wnt pathway inhibition.Cellular iron metabolism in prognosis and therapy of breast cancer.Intestinal iron homeostasis and colon tumorigenesisIron deprivation in cancer--potential therapeutic implicationsMacrophage-derived extracellular vesicle-packaged WNTs rescue intestinal stem cells and enhance survival after radiation injury.Identification of associations between small molecule drugs and miRNAs based on functional similarity.Iron chelators target both proliferating and quiescent cancer cells.Gene expression signature based screening identifies ribonucleotide reductase as a candidate therapeutic target in Ewing sarcoma.The iron chelator deferasirox induces apoptosis by targeting oncogenic Pyk2/β-catenin signaling in human multiple myeloma.Pharmacological modulation of beta-catenin and its applications in cancer therapyThe role of NDRG1 in the pathology and potential treatment of human cancers.Systems biological understanding of the regulatory network and the possible therapeutic strategies for vascular calcification.Iron and colorectal cancer: evidence from in vitro and animal studies.Phosphoproteome and transcription factor activity profiling identify actions of the anti-inflammatory agent UTL-5g in LPS stimulated RAW 264.7 cells including disrupting actin remodeling and STAT-3 activation.Mice lacking liver-specific β-catenin develop steatohepatitis and fibrosis after iron overload.Dysregulation of Iron Metabolism in Cholangiocarcinoma Stem-like Cells.
P2860
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P2860
Modulation of Wnt/β-catenin signaling and proliferation by a ferrous iron chelator with therapeutic efficacy in genetically engineered mouse models of cancer.
description
2011 nî lūn-bûn
@nan
2011年の論文
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2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
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2011年论文
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2011年论文
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name
Modulation of Wnt/β-catenin si ...... neered mouse models of cancer.
@ast
Modulation of Wnt/β-catenin si ...... neered mouse models of cancer.
@en
type
label
Modulation of Wnt/β-catenin si ...... neered mouse models of cancer.
@ast
Modulation of Wnt/β-catenin si ...... neered mouse models of cancer.
@en
prefLabel
Modulation of Wnt/β-catenin si ...... neered mouse models of cancer.
@ast
Modulation of Wnt/β-catenin si ...... neered mouse models of cancer.
@en
P2093
P2860
P50
P356
P1433
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Modulation of Wnt/β-catenin si ...... ineered mouse models of cancer
@en
P2093
A A Schmitt
C A Canning
N Banerjee
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P2888
P304
P356
10.1038/ONC.2011.228
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P577
2011-06-13T00:00:00Z