High-resolution protein complexes from integrating genomic information with molecular simulation.
about
Protein 3D structure computed from evolutionary sequence variationDirect-coupling analysis of residue coevolution captures native contacts across many protein familiesSequence co-evolutionary information is a natural partner to minimally-frustrated models of biomolecular dynamicsFrom residue coevolution to protein conformational ensembles and functional dynamics.PconsFold: improved contact predictions improve protein modelsConstructing sequence-dependent protein models using coevolutionary information.Proteins at work: a combined small angle X-RAY scattering and theoretical determination of the multiple structures involved on the protein kinase functional landscapeEmerging Computational Methods for the Rational Discovery of Allosteric Drugs.Fast and accurate multivariate Gaussian modeling of protein families: predicting residue contacts and protein-interaction partnersCombining Evolutionary Information and an Iterative Sampling Strategy for Accurate Protein Structure Prediction.Simultaneous identification of specifically interacting paralogs and interprotein contacts by direct coupling analysis.Native structure-based modeling and simulation of biomolecular systems per mouse click.From principal component to direct coupling analysis of coevolution in proteins: low-eigenvalue modes are needed for structure predictionStructure based design of protein linkers for zinc finger nuclease.Robust and accurate prediction of residue-residue interactions across protein interfaces using evolutionary information.Interaction fidelity in two-component signaling.SMOG@ctbp: simplified deployment of structure-based models in GROMACSBiophysics of protein evolution and evolutionary protein biophysicsA three-dimensional topology of complex I inferred from evolutionary correlations.Direct-Coupling Analysis of nucleotide coevolution facilitates RNA secondary and tertiary structure prediction.Coevolutionary Landscape Inference and the Context-Dependence of Mutations in Beta-Lactamase TEM-1.Inter-Protein Sequence Co-Evolution Predicts Known Physical Interactions in Bacterial Ribosomes and the Trp OperonTracking global changes induced in the CD4 T-cell receptor repertoire by immunization with a complex antigen using short stretches of CDR3 protein sequence.Excited states of ribosome translocation revealed through integrative molecular modeling.Coevolutionary analyses require phylogenetically deep alignments and better null models to accurately detect inter-protein contacts within and between species.Dimeric interactions and complex formation using direct coevolutionary couplings.Structural basis of histidine kinase autophosphorylation deduced by integrating genomics, molecular dynamics, and mutagenesisStatistical analyses of protein sequence alignments identify structures and mechanisms in signal activation of sensor histidine kinasesEvolutionary pressure on the topology of protein interface interaction networks.Connecting the Sequence-Space of Bacterial Signaling Proteins to Phenotypes Using Coevolutionary Landscapes.Elucidating the druggable interface of protein-protein interactions using fragment docking and coevolutionary analysis.Conservation of coevolving protein interfaces bridges prokaryote-eukaryote homologies in the twilight zone.Toward rationally redesigning bacterial two-component signaling systems using coevolutionary information.A tale of two machines: a review of the BLAST meeting, Tucson, AZ, 20-24 January 2013.Integrated strategy reveals the protein interface between cancer targets Bcl-2 and NAF-1.Challenges and advances in computational docking: 2009 in review.Large-scale identification of coevolution signals across homo-oligomeric protein interfaces by direct coupling analysis.Molecular Mechanisms of Two-Component Signal Transduction.Origins of coevolution between residues distant in protein 3D structures.Clustering-based model of cysteine co-evolution improves disulfide bond connectivity prediction and reduces homologous sequence requirements.
P2860
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P2860
High-resolution protein complexes from integrating genomic information with molecular simulation.
description
2009 nî lūn-bûn
@nan
2009 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
High-resolution protein comple ...... ion with molecular simulation.
@ast
High-resolution protein comple ...... ion with molecular simulation.
@en
type
label
High-resolution protein comple ...... ion with molecular simulation.
@ast
High-resolution protein comple ...... ion with molecular simulation.
@en
prefLabel
High-resolution protein comple ...... ion with molecular simulation.
@ast
High-resolution protein comple ...... ion with molecular simulation.
@en
P2860
P50
P356
P1476
High-resolution protein comple ...... ion with molecular simulation.
@en
P2093
Alexander Schug
Hendrik Szurmant
P2860
P304
22124-22129
P356
10.1073/PNAS.0912100106
P407
P577
2009-12-17T00:00:00Z