Metformin impairs glucose consumption and survival in Calu-1 cells by direct inhibition of hexokinase-II.
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Repurposing metformin: an old drug with new tricks in its binding pocketsDiabetes mellitus and metformin in hepatocellular carcinomaClinical significance of T cell metabolic reprogramming in cancerWarburg effect, hexokinase-II, and radioresistance of laryngeal carcinomaThe cellular and compartmental profile of mouse retinal glycolysis, tricarboxylic acid cycle, oxidative phosphorylation, and ~P transferring kinasesIn Vitro Anti-Echinococcal and Metabolic Effects of Metformin Involve Activation of AMP-Activated Protein Kinase in Larval Stages of Echinococcus granulosusBenserazide, a dopadecarboxylase inhibitor, suppresses tumor growth by targeting hexokinase 2.Modulation of glucose metabolism by a natural compound from Chloranthus japonicus via activation of AMP-activated protein kinaseMetformin disrupts malignant behavior of oral squamous cell carcinoma via a novel signaling involving Late SV40 factor/Aurora-A.Targeting hexokinase 2 inhibition promotes radiosensitization in HPV16 E7-induced cervical cancer and suppresses tumor growth.Type 2 Diabetes Mellitus and Cancer: The Role of Pharmacotherapy.Profiling and targeting of cellular bioenergetics: inhibition of pancreatic cancer cell proliferation.Metformin repositioning as antitumoral agent: selective antiproliferative effects in human glioblastoma stem cells, via inhibition of CLIC1-mediated ion currentIntravenous Vitamin C and Cancer: A Systematic Review.Obesity and Diabetes: The Increased Risk of Cancer and Cancer-Related Mortality.Fasting induces anti-Warburg effect that increases respiration but reduces ATP-synthesis to promote apoptosis in colon cancer models.Divergent targets of glycolysis and oxidative phosphorylation result in additive effects of metformin and starvation in colon and breast cancerDiscovery of a novel glucose metabolism in cancer: The role of endoplasmic reticulum beyond glycolysis and pentose phosphate shunt.Direct inhibition of hexokinase activity by metformin at least partially impairs glucose metabolism and tumor growth in experimental breast cancer.The mitochondrial permeability transition pore and its adaptive responses in tumor cells.The deep end of the metabolite pool: influences on epigenetic regulatory mechanisms in cancer.A Structural Basis for Biguanide Activity.Targeting cancer cell mitochondria as a therapeutic approach: recent updates.Effects on Energy Metabolism of Two Guanidine Molecules, (Boc)2 -Creatine and Metformin.Metformin in Lung Cancer: Review of in Vitro and in Vivo Animal Studies.Metformin and cancer: Technical and clinical implications for FDG-PET imaging.Metformin inhibits cell cycle progression of B-cell chronic lymphocytic leukemia cells.Effects of metformin and other biguanides on oxidative phosphorylation in mitochondria.Metformin transiently inhibits colorectal cancer cell proliferation as a result of either AMPK activation or increased ROS production.Mitochondrial Changes in Cancer.Up-regulation of hexokinase II contributes to rituximab-chemotherapy resistance and is a clinically relevant target for therapeutic development.Bioenergetic modulators hamper cancer cell viability and enhance response to chemotherapy.Pleiotropic Effects of Metformin on Cancer
P2860
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P2860
Metformin impairs glucose consumption and survival in Calu-1 cells by direct inhibition of hexokinase-II.
description
2013 nî lūn-bûn
@nan
2013 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Metformin impairs glucose cons ...... t inhibition of hexokinase-II.
@ast
Metformin impairs glucose cons ...... t inhibition of hexokinase-II.
@en
type
label
Metformin impairs glucose cons ...... t inhibition of hexokinase-II.
@ast
Metformin impairs glucose cons ...... t inhibition of hexokinase-II.
@en
prefLabel
Metformin impairs glucose cons ...... t inhibition of hexokinase-II.
@ast
Metformin impairs glucose cons ...... t inhibition of hexokinase-II.
@en
P2093
P2860
P50
P356
P1433
P1476
Metformin impairs glucose cons ...... ct inhibition of hexokinase-II
@en
P2093
Alberto Del Rio
Anna Maria Orengo
Barbara Salani
Gianmario Sambuceti
Sara Maffioli
P2860
P2888
P356
10.1038/SREP02070
P407
P50
P577
2013-01-01T00:00:00Z
P5875
P6179
1023507000