XRCC1 coordinates disparate responses and multiprotein repair complexes depending on the nature and context of the DNA damage - Test2 - elhamkhani - TriplyDB

XRCC1 coordinates disparate responses and multiprotein repair complexes depending on the nature and context of the DNA damage

XRCC1 coordinates disparate responses and multiprotein repair complexes depending on the nature and context of the DNA damage

http://www.wikidata.org/entity/Q33970153

about

Opposing roles of mitochondrial and nuclear PARP1 in the regulation of mitochondrial and nuclear DNA integrity: implications for the regulation of mitochondrial function Base excision repair X-ray repair cross complementing protein 1 in base excision repair.Base excision repair: a critical player in many games Pol β associated complex and base excision repair factors in mouse fibroblasts.Kinetics of endogenous mouse FEN1 in base excision repair.HSP90 regulates DNA repair via the interaction between XRCC1 and DNA polymerase β DNA ligase III acts as a DNA strand break sensor in the cellular orchestration of DNA strand break repair Interaction with OGG1 is required for efficient recruitment of XRCC1 to base excision repair and maintenance of genetic stability after exposure to oxidative stress New paradigms in the repair of oxidative damage in human genome: mechanisms ensuring repair of mutagenic base lesions during replication and involvement of accessory proteins.Disruption of PARP1 function inhibits base excision repair of a sub-set of DNA lesions Mammalian Base Excision Repair: Functional Partnership between PARP-1 and APE1 in AP-Site Repair.The XRCC1 phosphate-binding pocket binds poly (ADP-ribose) and is required for XRCC1 function.Micro-irradiation tools to visualize base excision repair and single-strand break repair Quantitative characterization of protein-protein complexes involved in base excision DNA repair The region of XRCC1 which harbours the three most common nonsynonymous polymorphic variants, is essential for the scaffolding function of XRCC1 Oxidative genome damage and its repair: implications in aging and neurodegenerative diseases.Base Excision Repair in the Mitochondria.Rules of engagement for base excision repair in chromatin The interaction between polynucleotide kinase phosphatase and the DNA repair protein XRCC1 is critical for repair of DNA alkylation damage and stable association at DNA damage sites Coordination of DNA repair by NEIL1 and PARP-1: a possible link to aging Distinct spatiotemporal patterns and PARP dependence of XRCC1 recruitment to single-strand break and base excision repair.Preventing oxidation of cellular XRCC1 affects PARP-mediated DNA damage responses.The role of DNA base excision repair in brain homeostasis and disease.Association between polymorphisms in DNA repair gene XRCC1 and non-melanoma skin cancer risk: a meta-analysis.p38 MAPK signaling and phosphorylations in the BRCT1 domain regulate XRCC1 recruitment to sites of DNA damage Overlapping roles for PARP1 and PARP2 in the recruitment of endogenous XRCC1 and PNKP into oxidized chromatin.Protecting DNA from errors and damage: an overview of DNA repair mechanisms in plants compared to mammals.Coordination of DNA single strand break repair.Poly(ADP-ribose) polymerase 1 escorts XPC to UV-induced DNA lesions during nucleotide excision repair.Principal Aspects Regarding the Maintenance of Mammalian Mitochondrial Genome Integrity.Kinetics of poly(ADP-ribosyl)ation, but not PARP1 itself, determines the cell fate in response to DNA damage in vitro and in vivo.XRCC1-mediated repair of strand breaks independent of PNKP binding.Application of Laser Micro-irradiation for Examination of Single and Double Strand Break Repair in Mammalian Cells.Monitoring of the spatial and temporal dynamics of BER/SSBR pathway proteins, including MYH, UNG2, MPG, NTH1 and NEIL1-3, during DNA replication.Anti-Cancer Potential of Homemade Fresh Garlic Extract Is Related to Increased Endoplasmic Reticulum Stress.Polymorphism of DNA repair genes OGG1, XRCC1, XPD and ERCC6 in bladder cancer in Belarus

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P2860

XRCC1 coordinates disparate responses and multiprotein repair complexes depending on the nature and context of the DNA damage

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2011 nî lūn-bûn

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2011 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2011 թվականի հուլիսին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

XRCC1 coordinates disparate re ...... and context of the DNA damage

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XRCC1 coordinates disparate re ...... and context of the DNA damage

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XRCC1 coordinates disparate re ...... and context of the DNA damage

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XRCC1 coordinates disparate re ...... and context of the DNA damage

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Environmental and Molecular Mutagenesis

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XRCC1 coordinates disparate re ...... and context of the DNA damage

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P2093

Audun Hanssen-Bauer

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David M Wilson

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Javier Peña-Diaz

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Karin Solvang-Garten

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Mansour Akbari

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Ottar Sundheim

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Sonja Andersen

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P2860

HMGB1 is a cofactor in mammalian base excision repair

Defective DNA single-strand break repair in spinocerebellar ataxia with axonal neuropathy-1

WRN helicase and FEN-1 form a complex upon replication arrest and together process branchmigrating DNA structures associated with the replication fork

XRCC1 is specifically associated with poly(ADP-ribose) polymerase and negatively regulates its activity following DNA damage

XRCC1 coordinates the initial and late stages of DNA abasic site repair through protein-protein interactions

XRCC1 co-localizes and physically interacts with PCNA

An interaction between the mammalian DNA repair protein XRCC1 and DNA ligase III

Early steps in the DNA base excision/single-strand interruption repair pathway in mammalian cells

PARP inhibition versus PARP-1 silencing: different outcomes in terms of single-strand break repair and radiation susceptibility

The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiology

P304

623-635

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scholarly article

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10.1002/EM.20663

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8

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P478

52

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Hans Einar Krokan

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2011-07-22T00:00:00Z

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51518611

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21786338

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3229989

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