Cellular IAPs inhibit a cryptic CD95-induced cell death by limiting RIP1 kinase recruitment - Test2 - elhamkhani - TriplyDB

Cellular IAPs inhibit a cryptic CD95-induced cell death by limiting RIP1 kinase recruitment

Cellular IAPs inhibit a cryptic CD95-induced cell death by limiting RIP1 kinase recruitment

http://www.wikidata.org/entity/Q33589801

about

S-nitrosylation of FLICE inhibitory protein determines its interaction with RIP1 and activation of NF-kappa B Smac mimetic bypasses apoptosis resistance in FADD- or caspase-8-deficient cells by priming for tumor necrosis factor α-induced necroptosis cIAPs block Ripoptosome formation, a RIP1/caspase-8 containing intracellular cell death complex differentially regulated by cFLIP isoforms cIAP1/2 are direct E3 ligases conjugating diverse types of ubiquitin chains to receptor interacting proteins kinases 1 to 4 (RIP1-4)Ripped to death Necroptosis in tumorigenesis, activation of anti-tumor immunity, and cancer therapy Molecular crosstalk between apoptosis, necroptosis, and survival signaling Necroptosis in acute kidney injury: a shedding light Ubiquitin-Mediated Regulation of Cell Death, Inflammation, and Defense of Homeostasis Inhibitor of apoptosis (IAP) proteins-modulators of cell death and inflammation Regulation of CD95/Fas signaling at the DISC Fueling the flames: Mammalian programmed necrosis in inflammatory diseases The two faces of receptor interacting protein kinase-1 Getting TRAIL back on track for cancer therapy Die another way--non-apoptotic mechanisms of cell death RIPK3 contributes to TNFR1-mediated RIPK1 kinase-dependent apoptosis in conditions of cIAP1/2 depletion or TAK1 kinase inhibition Catalytic activity of the caspase-8-FLIP(L) complex inhibits RIPK3-dependent necrosis Survival function of the FADD-CASPASE-8-cFLIP(L) complex cIAP1 and TAK1 protect cells from TNF-induced necrosis by preventing RIP1/RIP3-dependent reactive oxygen species production c-IAP1 and c-IAP2 redundancy differs between T and B cells.The linear ubiquitin chain assembly complex regulates TRAIL-induced gene activation and cell death.Inducing death in tumor cells: roles of the inhibitor of apoptosis proteins.Inhibitor of apoptosis proteins as therapeutic targets in multiple myeloma.The molecular regulation of programmed necrotic cell injury.The prevalence of TNFα-induced necrosis over apoptosis is determined by TAK1-RIP1 interplay.The caspase-8 inhibitor emricasan combines with the SMAC mimetic birinapant to induce necroptosis and treat acute myeloid leukemia.In TNF-stimulated cells, RIPK1 promotes cell survival by stabilizing TRAF2 and cIAP1, which limits induction of non-canonical NF-kappaB and activation of caspase-8 Regulating TRAIL receptor-induced cell death at the membrane : a deadly discussion Fas death receptor signalling: roles of Bid and XIAP.IAPs limit activation of RIP kinases by TNF receptor 1 during development.USP11-dependent selective cIAP2 deubiquitylation and stabilization determine sensitivity to Smac mimetics.The ratio of Mcl-1 and Noxa determines ABT737 resistance in squamous cell carcinoma of the skin Necroptosis: an alternative cell death program defending against cancer.IAP proteins as targets for drug development in oncology IAP antagonists sensitize murine osteosarcoma cells to killing by TNFα The Inhibitor of Apoptosis (IAPs) in Adaptive Response to Cellular Stress An initial phase of JNK activation inhibits cell death early in the endoplasmic reticulum stress response.Regulation of Apoptosis by Inhibitors of Apoptosis (IAPs)HDAC inhibitors enhance the lethality of low dose salinomycin in parental and stem-like GBM cells Inhibitor of apoptosis proteins: fascinating biology leads to attractive tumor therapeutic targets.

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Cellular IAPs inhibit a cryptic CD95-induced cell death by limiting RIP1 kinase recruitment

http://www.wikidata.org/entity/Q33589801

description

2009 nî lūn-bûn

@nan

2009 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2009年の論文

@ja

2009年論文

@yue

2009年論文

@zh-hant

2009年論文

@zh-hk

2009年論文

@zh-mo

2009年論文

@zh-tw

2009年论文

@wuu

name

Cellular IAPs inhibit a crypti ...... miting RIP1 kinase recruitment

@ast

Cellular IAPs inhibit a crypti ...... miting RIP1 kinase recruitment

@en

Cellular IAPs inhibit a crypti ...... iting RIP1 kinase recruitment.

@nl

type

label

Cellular IAPs inhibit a crypti ...... miting RIP1 kinase recruitment

@ast

Cellular IAPs inhibit a crypti ...... miting RIP1 kinase recruitment

@en

Cellular IAPs inhibit a crypti ...... iting RIP1 kinase recruitment.

@nl

prefLabel

Cellular IAPs inhibit a crypti ...... miting RIP1 kinase recruitment

@ast

Cellular IAPs inhibit a crypti ...... miting RIP1 kinase recruitment

@en

Cellular IAPs inhibit a crypti ...... iting RIP1 kinase recruitment.

@nl

P1433

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P1433

Journal of Cell Biology

P1476

Cellular IAPs inhibit a crypti ...... miting RIP1 kinase recruitment

@en

P2093

Beate Kellert

http://www.w3.org/2001/XMLSchema#string

Harald Gollnick

http://www.w3.org/2001/XMLSchema#string

Maria Feoktistova

http://www.w3.org/2001/XMLSchema#string

Martin Leverkus

http://www.w3.org/2001/XMLSchema#string

Peter Geserick

http://www.w3.org/2001/XMLSchema#string

P2860

The Hallmarks of Cancer

Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase RIP as effector molecule

IAP antagonists induce autoubiquitination of c-IAPs, NF-kappaB activation, and TNFalpha-dependent apoptosis

IAP antagonists target cIAP1 to induce TNFalpha-dependent apoptosis

Cellular signaling by fibroblast growth factor receptors

RIP: a novel protein containing a death domain that interacts with Fas/APO-1 (CD95) in yeast and causes cell death

Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes

TNF-alpha induces two distinct caspase-8 activation pathways

Palmitoylation of CD95 facilitates formation of SDS-stable receptor aggregates that initiate apoptosis signaling

Receptor interacting protein kinase-3 determines cellular necrotic response to TNF-alpha

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1037-1054

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scholarly article

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10.1083/JCB.200904158

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P433

7

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187

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P50

Maryline Moulin

W. Wei-Lynn Wong

P577

2009-12-01T00:00:00Z

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P5875

40805634

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P698

20038679

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P932

2806279

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