Triplication of a 21q22 region contributes to B cell transformation through HMGN1 overexpression and loss of histone H3 Lys27 trimethylation.
about
Down syndrome and leukemia: insights into leukemogenesis and translational targetsInterplay between H1 and HMGN epigenetically regulates OLIG1&2 expression and oligodendrocyte differentiation.The biology, pathogenesis and clinical aspects of acute lymphoblastic leukemia in children with Down syndrome.Transcriptomic Profiling and H3K27me3 Distribution Reveal Both Demethylase-Dependent and Independent Regulation of Developmental Gene Transcription in Cell Differentiation.Activity of the Type II JAK2 Inhibitor CHZ868 in B Cell Acute Lymphoblastic Leukemia.HMGN proteins modulate chromatin regulatory sites and gene expression during activation of naïve B cells.Inhibiting the oncogenic translation program is an effective therapeutic strategy in multiple myeloma.Determination of ETV6-RUNX1 genomic breakpoint by next-generation sequencing.Aneuploidy impairs hematopoietic stem cell fitness and is selected against in regenerating tissues in vivoMultivalent Chromatin Engagement and Inter-domain Crosstalk Regulate MORC3 ATPase.RAG1 targeting in the genome is dominated by chromatin interactions mediated by the non-core regions of RAG1 and RAG2.Efficient and rapid generation of large genomic variants in rats and mice using CRISMEREHaematopoietic development and leukaemia in Down syndrome.Novel methods and approaches to acute lymphoblastic leukemia drug discovery.Stem and progenitor cell dysfunction in human trisomies.Elevated HMGN4 expression potentiates thyroid tumorigenesis.Maintaining cell identity: PRC2-mediated regulation of transcription and cancer.Mouse-based genetic modeling and analysis of Down syndrome.Down syndrome and the complexity of genome dosage imbalance.Low risk of solid tumors in persons with Down syndrome.Cell-of-Origin-Specific 3D Genome Structure Acquired during Somatic Cell Reprogramming.Chromosomal Loop Domains Direct the Recombination of Antigen Receptor Genes.Drug sensitivity of single cancer cells is predicted by changes in mass accumulation rate.GSK-J4-Mediated Transcriptomic Alterations in Differentiating Embryoid Bodies.[Why have we only two P53 genes?]High-Mobility Group Nucleosome-Binding Protein 1 as Endogenous Ligand Induces Innate Immune Tolerance in a TLR4-Sirtuin-1 Dependent Manner in Human Blood Peripheral Mononuclear Cells.JAK2 is dispensable for maintenance of JAK2 mutant B-cell acute lymphoblastic leukemias
P2860
Q26770335-2358FB01-E1E4-42F0-AFBB-17117AE871FBQ30358182-DDDB1916-2D92-4532-9D6B-751E6738C7DEQ33698398-46D8FE28-11C8-4864-A277-53F8E87E2364Q35742850-97D44996-3306-4EE1-835A-512857C1A91AQ35861111-EEAA5335-E144-4302-B3BD-41836943F3A8Q35998650-031347DB-1744-4AF9-BD8D-31D232BC1D44Q36368265-41CA68A8-6568-4B9D-A7B2-5E75A5CA3FBDQ36528412-1A087671-CE7F-458E-8188-D229E896384EQ37051745-B616EA79-EE4F-4185-9981-AC6C74D6B67DQ37358050-AC5238EA-7366-44A5-837A-96E79FF13E2DQ37522927-0D8C8947-FE1D-437E-822A-4295D3E2A338Q37683801-37A56F59-F828-4ADF-AF29-184469A33935Q38243161-3842C14F-E70A-4483-9268-4484EF4C9058Q38248461-6941155B-189F-4732-9B4E-E4E362692A87Q38292512-F3F9FA97-3406-4612-A047-890432994CE5Q38716948-8EF6D38D-891F-4145-8725-7AC3A49400C6Q38961785-B6A5D98B-32E8-41A7-A8E5-983B09B576D2Q38993138-5AA2BEFB-F69C-4BC5-BE0C-919923FF19E2Q39060506-75F3484A-10DB-4A23-BFAA-4FAC821E7C46Q40506069-5A275F0D-7625-4A35-8560-163A4CA2F0D0Q41079240-CCA88DEF-F2B3-4400-8308-D3BEBA8A3B50Q41998609-FCDE350A-D8B8-40AC-9785-93D565736F4EQ42832493-891F1E32-A8B8-428C-8C1B-25841DCE4062Q47141091-43EB5FC0-C1D7-4CF5-98F0-C7E615738EDDQ50098064-A2264FE0-D91F-4810-B71C-16551501767FQ55000739-B397DA5E-1FB7-4362-B420-17590B306E31Q57272422-D40C3392-1D1E-4D89-9D12-61A67A28DD7F
P2860
Triplication of a 21q22 region contributes to B cell transformation through HMGN1 overexpression and loss of histone H3 Lys27 trimethylation.
description
2014 nî lūn-bûn
@nan
2014 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Triplication of a 21q22 region ...... stone H3 Lys27 trimethylation.
@ast
Triplication of a 21q22 region ...... stone H3 Lys27 trimethylation.
@en
type
label
Triplication of a 21q22 region ...... stone H3 Lys27 trimethylation.
@ast
Triplication of a 21q22 region ...... stone H3 Lys27 trimethylation.
@en
prefLabel
Triplication of a 21q22 region ...... stone H3 Lys27 trimethylation.
@ast
Triplication of a 21q22 region ...... stone H3 Lys27 trimethylation.
@en
P2093
P2860
P50
P356
P1433
P1476
Triplication of a 21q22 region ...... stone H3 Lys27 trimethylation.
@en
P2093
Akinori Yoda
Andrew A Lane
Anna C Schinzel
Bjoern Chapuy
Charles Y Lin
David M Weinstock
David Pellman
Diederik van Bodegom
Donna Neuberg
Elizabeth C Townsend
P2860
P2888
P304
P356
10.1038/NG.2949
P407
P577
2014-04-20T00:00:00Z