Parkin-mediated ubiquitin signalling in aggresome formation and autophagy.
about
The E3-ubiquitin ligase TRIM50 interacts with HDAC6 and p62, and promotes the sequestration and clearance of ubiquitinated proteins into the aggresomeMitofusin 1 and mitofusin 2 are ubiquitinated in a PINK1/parkin-dependent manner upon induction of mitophagyMechanisms for quality control of misfolded transmembrane proteinsCytoplasmic dynein is required for the spatial organization of protein aggregates in filamentous fungiProtein Aggregates Are Recruited to Aggresome by Histone Deacetylase 6 via Unanchored Ubiquitin C TerminiA Human Ubiquitin Conjugating Enzyme (E2)-HECT E3 Ligase Structure-function Screen14-3-3 protein targets misfolded chaperone-associated proteins to aggresomesVirology. Unanchored ubiquitin in virus uncoatingUbiquitination is involved in secondary growth, not initial formation of polyglutamine protein aggregates in C. elegans.Transcriptional analysis implicates endoplasmic reticulum stress in bovine spongiform encephalopathyMisfolded polypeptides are selectively recognized and transported toward aggresomes by a CED complexNuclear importation of Mariner transposases among eukaryotes: motif requirements and homo-protein interactions.Histone deacetylase inhibitors influence chemotherapy transport by modulating expression and trafficking of a common polymorphic variant of the ABCG2 efflux transporter.Polyglutamine toxicity is controlled by prion composition and gene dosage in yeast.p97-containing complexes in proliferation control and cancer: emerging culprits or guilt by association?Role of ubiquitin-proteasome-mediated proteolysis in nervous system disease.Parkin-mediated K63-polyubiquitination targets ubiquitin C-terminal hydrolase L1 for degradation by the autophagy-lysosome system.Misfolded proteins: from little villains to little helpers in the fight against cancer.Synergistic effects on dopamine cell death in a Drosophila model of chronic toxin exposure.Versatile roles of k63-linked ubiquitin chains in trafficking.Mutations associated with Charcot-Marie-Tooth disease cause SIMPLE protein mislocalization and degradation by the proteasome and aggresome-autophagy pathways.Diabetes and pancreatic exocrine dysfunction due to mutations in the carboxyl ester lipase gene-maturity onset diabetes of the young (CEL-MODY): a protein misfolding diseaseLK6/Mnk2a is a new kinase of alpha synuclein phosphorylation mediating neurodegenerationSOD1 aggregation in ALS mice shows simplistic test tube behavior.Stimulation of autophagy reduces neurodegeneration in a mouse model of human tauopathy.Parkin prevents cortical atrophy and Aβ-induced alterations of brain metabolism: ¹³C NMR and magnetic resonance imaging studies in AD models.CYLD, a deubiquitinase specific for lysine63-linked polyubiquitins, accumulates at the postsynaptic density in an activity-dependent mannerSevere growth deficiency is associated with STAT5b mutations that disrupt protein folding and activityCDC48 function during TMV infection: regulation of virus movement and replication by degradation?Ubiquilin/Dsk2 promotes inclusion body formation and vacuole (lysosome)-mediated disposal of mutated huntingtinThe benefits of local depletion: The centrosome as a scaffold for ubiquitin-proteasome-mediated degradationThe Relationship between Parkin and Protein Aggregation in Neurodegenerative Diseases.Mitochondrial contribution to Parkinson's disease pathogenesis.Autophagy, protein aggregation and hyperthermia: a mini-review.Cross-functional E3 ligases Parkin and C-terminus Hsp70-interacting protein in neurodegenerative disorders.E3 ubiquitin ligases in protein quality control mechanism.Autophagy coupling interplay: can improve cellular repair and aging?14-3-3 and aggresome formation: implications in neurodegenerative diseases.Nanomedicine and nanotoxicology: the pros and cons for neurodegeneration and brain cancer.Heat shock proteins in the context of photodynamic therapy: autophagy, apoptosis and immunogenic cell death.
P2860
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P2860
Parkin-mediated ubiquitin signalling in aggresome formation and autophagy.
description
2010 nî lūn-bûn
@nan
2010 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Parkin-mediated ubiquitin signalling in aggresome formation and autophagy.
@ast
Parkin-mediated ubiquitin signalling in aggresome formation and autophagy.
@en
type
label
Parkin-mediated ubiquitin signalling in aggresome formation and autophagy.
@ast
Parkin-mediated ubiquitin signalling in aggresome formation and autophagy.
@en
prefLabel
Parkin-mediated ubiquitin signalling in aggresome formation and autophagy.
@ast
Parkin-mediated ubiquitin signalling in aggresome formation and autophagy.
@en
P2860
P50
P356
P1476
Parkin-mediated ubiquitin signalling in aggresome formation and autophagy.
@en
P2860
P304
P356
10.1042/BST0380144
P577
2010-02-01T00:00:00Z