CENP-A is required for accurate chromosome segregation and sustained kinetochore association of BubR1.
about
The human Mis12 complex is required for kinetochore assembly and proper chromosome segregation.The constitutive centromere component CENP-50 is required for recovery from spindle damage.Centromere targeting of the chromosomal passenger complex requires a ternary subcomplex of Borealin, Survivin, and the N-terminal domain of INCENPChromatin Dynamics in Vivo: A Game of Musical ChairsThe CENP-H-I complex is required for the efficient incorporation of newly synthesized CENP-A into centromeresDrosophila CENP-A mutations cause a BubR1-dependent early mitotic delay without normal localization of kinetochore componentsDNA binding of centromere protein C (CENPC) is stabilized by single-stranded RNAA conserved arginine-rich motif within the hypervariable N-domain of Drosophila centromeric histone H3 (CenH3) mediates BubR1 recruitmentShRNA-targeted centromere protein A inhibits hepatocellular carcinoma growthA coordinated interdependent protein circuitry stabilizes the kinetochore ensemble to protect CENP-A in the human pathogenic yeast Candida albicansDe novo kinetochore assembly requires the centromeric histone H3 variant.A two-step mechanism for epigenetic specification of centromere identity and function.The quantitative architecture of centromeric chromatinCentromere identity, function, and epigenetic propagation across cell divisions.HJURP is a CENP-A chromatin assembly factor sufficient to form a functional de novo kinetochore.Systematic analysis in Caenorhabditis elegans reveals that the spindle checkpoint is composed of two largely independent branches.The chromatin remodelling complex NoRC safeguards genome stability by heterochromatin formation at telomeres and centromeres.Essential role for centromeric factors following p53 loss and oncogenic transformationHistone variant H2A.Z regulates centromere silencing and chromosome segregation in fission yeastThe kinetochoreCENP-A reduction induces a p53-dependent cellular senescence response to protect cells from executing defective mitoses.Dual recognition of CENP-A nucleosomes is required for centromere assembly.Centromere protein A dynamics in human pluripotent stem cell self-renewal, differentiation and DNA damage.The rapidly evolving centromere-specific histone has stringent functional requirements in Arabidopsis thaliana.The CNA1 histone of the ciliate Tetrahymena thermophila is essential for chromosome segregation in the germline micronucleusMCT-1 expression and PTEN deficiency synergistically promote neoplastic multinucleation through the Src/p190B signaling activation.A motif from Lys216 to Lys222 in human BUB3 protein is a nuclear localization signal and critical for BUB3 function in mitotic checkpoint.Stable complex formation of CENP-B with the CENP-A nucleosome.Centromeric chromatin and the pathway that drives its propagation.CENP-C is involved in chromosome segregation, mitotic checkpoint function, and kinetochore assembly.Repeat Composition of CenH3-chromatin and H3K9me2-marked heterochromatin in Sugar Beet (Beta vulgaris).Heterochromatin protein 1alpha: a hallmark of cell proliferation relevant to clinical oncology.HJURP is involved in the expansion of centromeric chromatin.Propagation of centromeric chromatin requires exit from mitosis.Stepwise unfolding supports a subunit model for vertebrate kinetochoresWhole-proteome genetic analysis of dependencies in assembly of a vertebrate kinetochore.The CCAN recruits CENP-A to the centromere and forms the structural core for kinetochore assembly.Dynamics of inner kinetochore assembly and maintenance in living cells.How to build a centromere: from centromeric and pericentromeric chromatin to kinetochore assembly.Epigenetic aberrations and cancer.
P2860
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P2860
CENP-A is required for accurate chromosome segregation and sustained kinetochore association of BubR1.
description
2005 nî lūn-bûn
@nan
2005 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
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name
CENP-A is required for accurat ...... etochore association of BubR1.
@ast
CENP-A is required for accurat ...... etochore association of BubR1.
@en
type
label
CENP-A is required for accurat ...... etochore association of BubR1.
@ast
CENP-A is required for accurat ...... etochore association of BubR1.
@en
prefLabel
CENP-A is required for accurat ...... etochore association of BubR1.
@ast
CENP-A is required for accurat ...... etochore association of BubR1.
@en
P2093
P2860
P50
P1476
CENP-A is required for accurat ...... etochore association of BubR1.
@en
P2093
Elizabeth Burns
Paola Vagnarelli
Tatiana Zerjal
Tatsuo Fukagawa
Vinciane Régnier
P2860
P304
P356
10.1128/MCB.25.10.3967-3981.2005
P407
P577
2005-05-01T00:00:00Z