SIRT6 promotes DNA repair under stress by activating PARP1
about
Knock-in reporter mice demonstrate that DNA repair by non-homologous end joining declines with ageThe histone deacetylase SIRT6 is a tumor suppressor that controls cancer metabolismPARP1-dependent recruitment of KDM4D histone demethylase to DNA damage sites promotes double-strand break repairSIRT6 overexpression induces massive apoptosis in cancer cells but not in normal cellsEffects of Oxidative Stress on Mesenchymal Stem Cell BiologyPotential Modulation of Sirtuins by Oxidative StressIntracellular Mono-ADP-Ribosylation in Signaling and DiseaseProtective effects and mechanisms of sirtuins in the nervous systemSirtuin 1 and sirtuin 3: physiological modulators of metabolismThe controversial world of sirtuinsSIRT1 as a therapeutic target in inflammaging of the pulmonary diseaseTargeting histone deacetylases for cancer therapy: from molecular mechanisms to clinical implicationsPleiotropic cellular functions of PARP1 in longevity and aging: genome maintenance meets inflammationMetabolic modulation of chromatin: implications for DNA repair and genomic integrityMetabolism, longevity and epigeneticsSIRTain regulators of premature senescence and accelerated agingSirtuins in Cancer: a Balancing Act between Genome Stability and MetabolismDNA damage and repair in atherosclerosis: current insights and future perspectivesSirtuins, metabolism, and DNA repairRedox regulation of SIRT1 in inflammation and cellular senescenceSirtuins in epigenetic regulationSirtuin-dependent epigenetic regulation in the maintenance of genome integrityImpacts on Sirtuin Function and Bioavailability of the Dietary Bioactive Compound DihydrocoumarinThe role of sirtuins in cardiac diseaseSirtuins in metabolism, DNA repair and cancerImmune Cell Regulatory Pathways Unexplored as Host-Directed Therapeutic Targets for Mycobacterium tuberculosis: An Opportunity to Apply Precision Medicine Innovations to Infectious DiseasesCircadian molecular clock in lung pathophysiologySIRT6 is required for maintenance of telomere position effect in human cellsSIRT6 protects human endothelial cells from DNA damage, telomere dysfunction, and senescencePrevention of chemotherapy-induced ovarian damage: possible roles for hormonal and non-hormonal attenuating agentsA human tRNA synthetase is a potent PARP1-activating effector target for resveratrolSlowing ageing by design: the rise of NAD(+) and sirtuin-activating compoundsOxygen consumption and usage during physical exercise: the balance between oxidative stress and ROS-dependent adaptive signalingNuclear DNA damage signalling to mitochondria in ageingOver expression of wild type or a catalytically dead mutant of Sirtuin 6 does not influence NFκB responsesNAD(P)H:quinone oxidoreductase 1 (NQO1) localizes to the mitotic spindle in human cellsGemcitabine induces poly (ADP-ribose) polymerase-1 (PARP-1) degradation through autophagy in pancreatic cancerSam68 Is Required for DNA Damage Responses via Regulating Poly(ADP-ribosyl)ationSIRT4 has tumor-suppressive activity and regulates the cellular metabolic response to DNA damage by inhibiting mitochondrial glutamine metabolismRAD6 promotes homologous recombination repair by activating the autophagy-mediated degradation of heterochromatin protein HP1.
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P2860
SIRT6 promotes DNA repair under stress by activating PARP1
description
2011 nî lūn-bûn
@nan
2011 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
SIRT6 promotes DNA repair under stress by activating PARP1
@ast
SIRT6 promotes DNA repair under stress by activating PARP1
@en
type
label
SIRT6 promotes DNA repair under stress by activating PARP1
@ast
SIRT6 promotes DNA repair under stress by activating PARP1
@en
prefLabel
SIRT6 promotes DNA repair under stress by activating PARP1
@ast
SIRT6 promotes DNA repair under stress by activating PARP1
@en
P2093
P2860
P356
P1433
P1476
SIRT6 promotes DNA repair under stress by activating PARP1
@en
P2093
Amita Vaidya
Andrei Seluanov
Christopher Hine
Matthew Au
Michael Van Meter
Vera Gorbunova
Zhiyong Mao
P2860
P304
P356
10.1126/SCIENCE.1202723
P407
P50
P577
2011-06-01T00:00:00Z