Microbial genome mining for accelerated natural products discovery: is a renaissance in the making?
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Self-resistance in Streptomyces, with Special Reference to β-Lactam AntibioticsIntegrated (Meta) Genomic and Synthetic Biology Approaches to Develop New BiocatalystsDiscovery Strategies of Bioactive Compounds Synthesized by Nonribosomal Peptide Synthetases and Type-I Polyketide Synthases Derived from Marine Microbiomes.Cold and Hot Extremozymes: Industrial Relevance and Current TrendsThe Sound of Silence: Activating Silent Biosynthetic Gene Clusters in Marine MicroorganismsGenome Analysis of the Fruiting Body-Forming Myxobacterium Chondromyces crocatus Reveals High Potential for Natural Product Biosynthesis.Application of Omics Technologies for Evaluation of Antibacterial Mechanisms of Action of Plant-Derived ProductsDirected natural product biosynthesis gene cluster capture and expression in the model bacterium Bacillus subtilisActivation of a plasmid-situated type III PKS gene cluster by deletion of a wbl gene in deepsea-derived Streptomyces somaliensis SCSIO ZH66Phylogenomic Analysis of Natural Products Biosynthetic Gene Clusters Allows Discovery of Arseno-Organic Metabolites in Model StreptomycetesDiscovery of Antimycin-Type Depsipeptides from a wbl Gene Mutant Strain of Deepsea-Derived Streptomyces somaliensis SCSIO ZH66 and Their Effects on Pro-inflammatory Cytokine Production.Strong antibiotic production is correlated with highly active oxidative metabolism in Streptomyces coelicolor M145Strain prioritization for natural product discovery by a high-throughput real-time PCR method.An atypical orphan carbohydrate-NRPS genomic island encodes a novel lytic transglycosylaseBiosynthesis of akaeolide and lorneic acids and annotation of type I polyketide synthase gene clusters in the genome of Streptomyces sp. NPS554.Enediynes: Exploration of microbial genomics to discover new anticancer drug leads.Molecular networking and pattern-based genome mining improves discovery of biosynthetic gene clusters and their products from Salinispora species.Targeted capture and heterologous expression of the Pseudoalteromonas alterochromide gene cluster in Escherichia coli represents a promising natural product exploratory platform.Hexacyclopeptides secreted by an endophytic fungus Fusarium solani N06 act as crosstalk molecules in Narcissus tazetta.High-efficiency multiplex genome editing of Streptomyces species using an engineered CRISPR/Cas system.Discovery of phosphonic acid natural products by mining the genomes of 10,000 actinomycetes.Linking Biosynthetic Gene Clusters to their Metabolites via Pathway- Targeted Molecular Networking.Precise cloning and tandem integration of large polyketide biosynthetic gene cluster using Streptomyces artificial chromosome system.Evolution of chemical diversity by coordinated gene swaps in type II polyketide gene clusters.Reinvigorating natural product combinatorial biosynthesis with synthetic biologyMetabologenomics: Correlation of Microbial Gene Clusters with Metabolites Drives Discovery of a Nonribosomal Peptide with an Unusual Amino Acid MonomerFunctional Genome Mining for Metabolites Encoded by Large Gene Clusters through Heterologous Expression of a Whole-Genome Bacterial Artificial Chromosome Library in Streptomyces spp.Simple and rapid direct cloning and heterologous expression of natural product biosynthetic gene cluster in Bacillus subtilis via Red/ET recombineering.Spontaneous and induced mutations to rifampicin, streptomycin and spectinomycin resistances in actinomycetes: mutagenic mechanisms and applications for strain improvement.Antibacterial products of marine organisms.Toward a new focus in antibiotic and drug discovery from the Streptomyces arsenalGlycosyltransferases: mechanisms and applications in natural product development.Genetic manipulation of secondary metabolite biosynthesis for improved production in Streptomyces and other actinomycetes.Genetic engineering of modular PKSs: from combinatorial biosynthesis to synthetic biology.Retrospective analysis of natural products provides insights for future discovery trends.The structure of RbmB from Streptomyces ribosidificus, an aminotransferase involved in the biosynthesis of ribostamycin.Labradorins with Antibacterial Activity Produced by Pseudomonas sp.The Antibiotic Resistant Target Seeker (ARTS), an exploration engine for antibiotic cluster prioritization and novel drug target discovery.The evolution of genome mining in microbes - a review.Modern mass spectrometry for synthetic biology and structure-based discovery of natural products.
P2860
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P2860
Microbial genome mining for accelerated natural products discovery: is a renaissance in the making?
description
2013 nî lūn-bûn
@nan
2013 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Microbial genome mining for ac ...... s a renaissance in the making?
@ast
Microbial genome mining for ac ...... s a renaissance in the making?
@en
type
label
Microbial genome mining for ac ...... s a renaissance in the making?
@ast
Microbial genome mining for ac ...... s a renaissance in the making?
@en
prefLabel
Microbial genome mining for ac ...... s a renaissance in the making?
@ast
Microbial genome mining for ac ...... s a renaissance in the making?
@en
P2093
P2860
P1476
Microbial genome mining for ac ...... s a renaissance in the making?
@en
P2093
Brian O Bachmann
Richard H Baltz
Steven G Van Lanen
P2860
P304
P356
10.1007/S10295-013-1389-9
P577
2013-12-17T00:00:00Z