Multi-faceted regulation of gamma-glutamylcysteine synthetase.
about
Knockdown of glutamate-cysteine ligase by small hairpin RNA reveals that both catalytic and modulatory subunits are essential for the survival of primary neuronsStructure, function, and post-translational regulation of the catalytic and modifier subunits of glutamate cysteine ligaseRegulation of glutathione synthesisHeterogeneous role of the glutathione antioxidant system in modulating the response of ESFT to fenretinide in normoxia and hypoxiaTranssulfuration pathway thiols and methylated arginines: the Hunter Community StudyInitial characterization of the glutamate-cysteine ligase modifier subunit Gclm(-/-) knockout mouse. Novel model system for a severely compromised oxidative stress responseClinical and biochemical correlates of serum L-ergothioneine concentrations in community-dwelling middle-aged and older adultsVitamin E deficiency induces liver nuclear factor-kappaB DNA-binding activity and changes in related genesDifferential regulation of glutamate-cysteine ligase subunit expression and increased holoenzyme formation in response to cysteine deprivationGonadotropin regulation of glutamate cysteine ligase catalytic and modifier subunit expression in rat ovary is subunit and follicle stage specificTemporal and spatial patterns of ovarian gene transcription following an ovulatory dose of gonadotropin in the ratThe modifier subunit of Drosophila glutamate-cysteine ligase regulates catalytic activity by covalent and noncovalent interactions and influences glutathione homeostasis in vivo.An intracellular antioxidant determines the expression of a melanin-based signal in a birdMuscarinic receptors prevent oxidative stress-mediated apoptosis induced by domoic acid in mouse cerebellar granule cells.Mechanisms of gamma-glutamylcysteine ligase regulationDevelopmental potential of prepubertal mouse oocytes is compromised due mainly to their impaired synthesis of glutathione.Loss of NRF2 impairs gastric nitrergic stimulation and function.Cytoprotection against oxidative stress and the regulation of glutathione synthesis.Caspase-3-Dependent Cleavage of the Glutamate-L-Cysteine Ligase Catalytic Subunit during Apoptotic Cell DeathImpaired glutathione synthesis in schizophrenia: convergent genetic and functional evidence.Zinc and cancer: implications for LIV-1 in breast cancer.Transforming growth factor β suppresses glutamate-cysteine ligase gene expression and induces oxidative stress in a lung fibrosis modelGlutathione and modulation of cell apoptosis.Sulfur assimilation and glutathione metabolism under cadmium stress in yeast, protists and plants.Oxidative stress and glutathione response in tissue cultures from persons with major depressionLow-level domoic acid protects mouse cerebellar granule neurons from acute neurotoxicity: role of glutathionePro-oxidant shift in glutathione redox state during aging.Overexpression of glutamate-cysteine ligase protects human COV434 granulosa tumour cells against oxidative and gamma-radiation-induced cell death.Submicromolar concentrations of 4-hydroxynonenal induce glutamate cysteine ligase expression in HBE1 cells.Transcriptional regulation of rat gamma-glutamate cysteine ligase catalytic subunit gene is mediated through a distal antioxidant response element.Crystal structure of gamma-glutamylcysteine synthetase: insights into the mechanism of catalysis by a key enzyme for glutathione homeostasis.The role of metallothionein in oxidative stressCertain carotenoids enhance the intracellular glutathione level in a murine cultured macrophage cell line by inducing glutamate-cysteine-ligase.Upregulation of gamma-glutamate-cysteine ligase as part of the long-term adaptation process to iron accumulation in neuronal SH-SY5Y cells.Genetic and environmental factors influencing glutathione homeostasis in Saccharomyces cerevisiae.Drosophila melanogaster glutamate-cysteine ligase activity is regulated by a modifier subunit with a mechanism of action similar to that of the mammalian form.Diminished immunoreactivity of gamma-glutamylcysteine synthetase in the airways of smokers' lung.Glutathione (GSH) concentrations vary with the cell cycle in maturing hamster oocytes, zygotes, and pre-implantation stage embryos.Bird population declines due to radiation exposure at Chernobyl are stronger in species with pheomelanin-based coloration.Endothelial dysfunction and reduced antioxidant protection in an animal model of the developmental origins of cardiovascular disease.
P2860
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P2860
Multi-faceted regulation of gamma-glutamylcysteine synthetase.
description
2000 nî lūn-bûn
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2000 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Multi-faceted regulation of gamma-glutamylcysteine synthetase.
@ast
Multi-faceted regulation of gamma-glutamylcysteine synthetase.
@en
type
label
Multi-faceted regulation of gamma-glutamylcysteine synthetase.
@ast
Multi-faceted regulation of gamma-glutamylcysteine synthetase.
@en
prefLabel
Multi-faceted regulation of gamma-glutamylcysteine synthetase.
@ast
Multi-faceted regulation of gamma-glutamylcysteine synthetase.
@en
P2093
P2860
P1476
Multi-faceted regulation of gamma-glutamylcysteine synthetase.
@en
P2093
Freeman ML
Meredith MJ
Soltaninassab SR
P2860
P304
P356
10.1002/(SICI)1097-4652(200002)182:2<163::AID-JCP4>3.0.CO;2-1
P577
2000-02-01T00:00:00Z