With TOR, less is more: a key role for the conserved nutrient-sensing TOR pathway in aging - Test2 - elhamkhani - TriplyDB

With TOR, less is more: a key role for the conserved nutrient-sensing TOR pathway in aging

With TOR, less is more: a key role for the conserved nutrient-sensing TOR pathway in aging

http://www.wikidata.org/entity/Q33912952

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Icariin and its derivative icariside II extend healthspan via insulin/IGF-1 pathway in C. elegans Lessons from C. elegans: signaling pathways for longevity mTOR signaling in growth control and disease The crucial impact of lysosomes in aging and longevity Live strong and prosper: the importance of skeletal muscle strength for healthy ageing Linking diet to acne metabolomics, inflammation, and comedogenesis: an update Milk--A Nutrient System of Mammalian Evolution Promoting mTORC1-Dependent Translation Metabolic homeostasis as the cornerstone of aging Nutrient control of Drosophila longevity Histone methylation makes its mark on longevity Aging signaling pathways and circadian clock-dependent metabolic derangements Modelling age-related metabolic disorders in the mouse The pathogenic role of persistent milk signaling in mTORC1- and milk-microRNA-driven type 2 diabetes mellitus Angiotensin Converting Enzyme (ACE) Inhibitor Extends Caenorhabditis elegans Life Span The MDT-15 subunit of mediator interacts with dietary restriction to modulate longevity and fluoranthene toxicity in Caenorhabditis elegans The circadian clock coordinates ribosome biogenesis Dietary restriction induced longevity is mediated by nuclear receptor NHR-62 in Caenorhabditis elegans Targeting the prodromal stage of Alzheimer's disease: bioenergetic and mitochondrial opportunities Lifespan extension in a semelparous chordate occurs via developmental growth arrest just prior to meiotic entry Role of the hypothalamus in mediating protective effects of dietary restriction during aging A genome-wide immunodetection screen in S. cerevisiae uncovers novel genes involved in lysosomal vacuole function and morphology Potential therapeutic effects of the MTOR inhibitors for preventing ageing and progeria-related disorders Mechanisms of aging-related proteinopathies in Caenorhabditis elegans Cytoplasmic mRNA turnover and ageing Methionine restriction and life-span control Transcriptional and epigenetic regulation of autophagy in aging TOR signaling and rapamycin influence longevity by regulating SKN-1/Nrf and DAF-16/FoxO Haploinsufficiency of akt1 prolongs the lifespan of mice Mitochondrial dysfunction in cardiac aging Down-regulating sphingolipid synthesis increases yeast lifespan Deep Proteome Analysis Identifies Age-Related Processes in C. elegans C. elegans S6K Mutants Require a Creatine-Kinase-like Effector for Lifespan Extension The African Turquoise Killifish Genome Provides Insights into Evolution and Genetic Architecture of Lifespan.10-Hydroxy-2-decenoic Acid, the Major Lipid Component of Royal Jelly, Extends the Lifespan of Caenorhabditis elegans through Dietary Restriction and Target of Rapamycin Signaling Six plant extracts delay yeast chronological aging through different signaling pathways Discovery of plant extracts that greatly delay yeast chronological aging and have different effects on longevity-defining cellular processes Autophagy and metabolism Rapamycin extends murine lifespan but has limited effects on aging.Spatial sequestration of misfolded proteins by a dynamic chaperone pathway enhances cellular fitness during stress.The anti-aging effects of LW-AFC via correcting immune dysfunctions in senescence accelerated mouse resistant 1 (SAMR1) strain

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With TOR, less is more: a key role for the conserved nutrient-sensing TOR pathway in aging

http://www.wikidata.org/entity/Q33912952

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2010 nî lūn-bûn

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2010 թուականի Յունիսին հրատարակուած գիտական յօդուած

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2010 թվականի հունիսին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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With TOR, less is more: a key ...... t-sensing TOR pathway in aging

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With TOR, less is more: a key ...... t-sensing TOR pathway in aging

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With TOR, less is more: a key ...... t-sensing TOR pathway in aging

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With TOR, less is more: a key ...... t-sensing TOR pathway in aging

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J.CMET.2010.05.001

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Cell Metabolism

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With TOR, less is more: a key ...... t-sensing TOR pathway in aging

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Aric N Rogers

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Di Chen

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Emma L Thomas

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Lutz Kockel

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Pankaj Kapahi

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Patrick Wai-Lun Li

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Subhash D Katewa

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P2860

Calories do not explain extension of life span by dietary restriction in Drosophila

Life span extension by calorie restriction depends on Rim15 and transcription factors downstream of Ras/PKA, Tor, and Sch9

PML inhibits HIF-1alpha translation and neoangiogenesis through repression of mTOR

DEPTOR is an mTOR inhibitor frequently overexpressed in multiple myeloma cells and required for their survival

Two TOR complexes, only one of which is rapamycin sensitive, have distinct roles in cell growth control

The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1

AMPK phosphorylation of raptor mediates a metabolic checkpoint

Extension of chronological life span in yeast by decreased TOR pathway signaling

Regulation of mTOR function in response to hypoxia by REDD1 and the TSC1/TSC2 tumor suppressor complex

mTOR is essential for growth and proliferation in early mouse embryos and embryonic stem cells

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453-465

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10.1016/J.CMET.2010.05.001

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6

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2010-06-01T00:00:00Z

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44645717

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20519118

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2885591

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